1.Comparing MSCT with MRI in preoperative staging of laryngeal carcinoma
Jianxiu XUE ; Runqing DUAN ; Bei ZHAO ; Chengjie MA ; Chuanjian Lü
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009;(24):1134-1137,1142
Objective:To investigate the value of MRI and MSCT in TNM staging of laryngocarcinoma.Method:Thirty-seven patients with laryngocarcinoma were underwent by contrast enhanced scan and muhiplanar reconstruction.Thirty-five patients with laryngocarcinoma were underwent contrast enhanced muhislice spiral CT,which of them were done by MPR.There are 28 cases which were scan by MRI and MSCT in the two former nd we contrasted the accuracy rating in laryngeal manifestation of abnormality.In the former two groups,we observed them the variability in the aspect of lymphaden metabasis and TNM staging.Result:In all 28 cases,the MRI had better accuracy rating in displaying the parts of preepiglottic space,larynx side interspace,lingual root,eck tissue,vocal cord.In the TNM staging,there was no difference in stage one in accuracy rating,as the stag stepping up,the accuracy rating of MRI had became better.The last result was that the two methods had difference in staging.In the two methods,MSCT had better sensitivity,specificity and accuracy rating.Conclusion:RI and MSCT had good accuracy rating in TNM staging,MRI has better accuracy rating in some of laryngeal,but as the lymphaden metabasis,the MSCT was better.There were variability in staging,and the MRI was better.
2.Study on the Correlation of Spiral CT Features with Expression of E-cadherin in Peripheral Lung Cancer
Chuanjian Lü ; Yamin WAN ; Xuejun CHEN ; Dapeng SHI
Journal of Practical Radiology 2010;26(1):24-27
Objective To investigate the correlation of spiral CT features with expression of E-cadherin(E-cad) in peripheral lung cancer.Methods Spiral CT scans were performed in 58 patients with peripheral lung cancer confirmed by pathology.Expression of E-cad in 58 cases were detected with SP immunohistochemical techniques.Spiral CT findings were compared with expression of E-cad.Results The abnormal expression of E-cad was showed in 32 cases(55.17%).The positive rates of E-cad expression were 40.63% in I-II cell differentiation group and 73.08% in III-IV cell differentiation group,and the difference was significant(P<0.05).The abnormal expression of E-cad was associated with the CT features,such as lymph node metastasis,pleural invasion and the size of tumor(P<0.05),but not the cavity sign,spicular sign and vessel convergence sign(P>0.05).Conclusion E-cad gene over expression may play an important role in the pathogenesis and CT appearances of lung cancer.
3.Comparing MSCT with MRI in preoperative staging of laryngeal carcinoma.
Jianxiu XUE ; Runqing DUAN ; Bei ZHAO ; Chengjie MA ; Chuanjian LÜ
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009;23(24):1134-1142
OBJECTIVE:
To investigate the value of MRI and MSCT in TNM staging of laryngocarcinoma.
METHOD:
Thirty-seven patients with laryngocarcinoma were underwent by contrast enhanced scan and multiplanar reconstruction. Thirty-five patients with laryngocarcinoma were underwent contrast enhanced multislice spiral CT, which of them were done by MPR. There are 28 cases which were scan by MRI and MSCT in the two former and we contrasted the accuracy rating in laryngeal manifestation of abnormality. In the former two groups, we observed them the variability in the aspect of lymphaden metastasis and TNM staging.
RESULT:
In all 28 cases, the MRI had better accuracy rating in displaying the parts of preepiglottic space, larynx side interspace, lingual root, neck tissue, vocal cord. In the TNM staging, there was no difference in stage one in accuracy rating, as the stag stepping up, the accuracy rating of MRI had became better. The last result was that the two methods had difference in staging. In the two methods, MSCT had better sensitivity, specificity and accuracy rating.
CONCLUSION
MRI and MSCT had good accuracy rating in TNM staging, MRI has better accuracy rating in some of laryngeal, but as the lymphaden metastasis, the MSCT was better. There were variability in staging, and the MRI was better.
Adult
;
Carcinoma, Squamous Cell
;
diagnostic imaging
;
pathology
;
Female
;
Humans
;
Laryngeal Neoplasms
;
diagnostic imaging
;
pathology
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Neoplasm Staging
;
Tomography, Spiral Computed