1.Problems and countermeasures for application management of military medical equipment
Chinese Medical Equipment Journal 1993;0(05):-
The application of military medical equipment highly influences the effect of medical support.According to the investigation in the affiliated basic units,this paper puts forward improvement measures for the existing problems in the application of military medical equipment.
2.Promoting strategic information reservation of medicinal materials through online purchasing platform for medical resources
Chinese Medical Equipment Journal 2004;0(07):-
Strategic information reservation of medicinal materials is complementary to the strategic reservation of medicinal materials itself.This article discusses the advantages and disadvantages of the reservation of physical medicinal goods and mobilization of medical resources for national defense.The construction mode and operational characteristics of the information database for the strategic reservation of medicinal materials have also been discussed as well as the great significance of its widely application to the information reservation of medicinal materials.
3.Clinical Observations on Combined Acupuncture and Medicine for the Treatment of Kidney Deficiency and Phlegm ;Dampness Syndrome in Obese Polycystic Ovary Syndrome
Lingyun ZHOU ; Chuanhua XU ; Shuping LI
Shanghai Journal of Acupuncture and Moxibustion 2016;35(10):1213-1215
Objective To investigate the clinical efficacy of combined acupuncture and medicine in treating kidney deficiency and phlegm dampness syndrome in obese polycystic ovary syndrome. Method Sixty-four patients were randomly allocated to two groups. The treatment group received combined acupuncture and medicine and the control group, oral administration of metformin. The course of treatment was three months. Pre-treatment and post-treatment indicators were statistically analyzed in the two groups of patients. Result BMI, waist to hip ratio, fasting insulin, fasting blood glucose and HOMA-IR improved significantly in the treatment group of patients after treatment; there were statistically significant pre-/post-treatment differences (P<0.05). Post-treatment BMI and waist to hip ratio improved more markedly in the treatment group than in the control group (P<0.05). Conclusion Combined acupuncture and medicine has a better therapeutic effect on kidney deficiency and phlegm dampness syndrome in obese polycystic ovary syndrome.
4.Joinpoint regression analysis for the trends of cervical cancer mortality between 1987-2014 in China
Wei ZHOU ; Zhijiang ZHANG ; Lijun WANG ; Xiaoxue LIU ; Chuanhua YU
China Oncology 2017;27(8):634-640
Background and purpose: Cervical cancer is one of the most common malignant tumors and poses a great threat to women's fitness. Monitoring its present status and variations over the past 3 decades could provide scientific basis for prevention and control strategies of cervical cancer in China. Methods: This study collected the mortality rates of cervical cancer data in Chinese women from 1987 to 2014, described the features and trends of age-standardized rates and truncated rates, and estimated the variations via joinpoint regression models. Results:The mortality rates of cervical cancer for rural women were roughly higher than those for urban women. It showed downward trends for both urban and rural women, and the average rate of decrease for rural women (AAPC=3.94%, P<0.01) was higher than that for urban women (AAPC=1.79%, P<0.01). The gap between urban and rural areas was narrowing, with urban rates exceeding rural rates after 2010. The mortality rates of cervical cancer increased with time for urban women aged from 30 to 54, decreased with time for the elderly urban women and all the rural women. Conclusion: The overall mortality rates of cervical cancer took a desirable turn in China over the past 3 decades, while the status for the middle-aged urban women was getting worse as well as the elderly in both urban and rural areas during the past 10 years.
5.Molecular cloning and characterization of a N-acetylneuraminate lyase gene from Staphylococcus hominis.
Chuanhua ZHOU ; Xi CHEN ; Jinhui FENG ; Dongguang XIAO ; Qiaqing WUZ ; Dunming ZHU
Chinese Journal of Biotechnology 2013;29(4):480-489
A N-acetylneuraminate lyase gene (shnal) from Staphylococcus hominis was cloned into pET-28a and expressed in Escherichia coli BL21 (DE3) host cells. The recombinant enzyme was purified and characterized. It is a homotetrameric enzyme with the optimum pH at 8.0 for the cleavage direction and the optimum pH and temperature were 7.5 and 45 degrees C for the synthetic direction. The activity of ShNAL is stable when incubated at 45 degrees C for 2 h but decreased rapidly over 50 degrees C. ShNAL showed high stability in a wide range pH from 5.0 to 10.0 with the residual activity being > 70% when the enzyme was incubated in different buffers at 4 degrees C for 24 h. Its K(m) towards N-acetylneuraminic acid, pyruvate and ManNAc were (4.0 +/- 0.2) mmol/L, (35.1 +/- 3.2) mmol/L and (131.7 +/- 12.1) mmol/L, respectively. The k(cat)/K(m) value of Neu5Ac, ManNAc, and Pyr for ShNAL were 1.9 L/(mmol x s), 0.08 L/(mmol x s) and 0.08 L/(mmol x s), respectively.
Bacterial Proteins
;
genetics
;
metabolism
;
Cloning, Molecular
;
Enzyme Stability
;
Escherichia coli
;
genetics
;
metabolism
;
Hydrogen-Ion Concentration
;
Oxo-Acid-Lyases
;
genetics
;
metabolism
;
Recombinant Proteins
;
genetics
;
metabolism
;
Staphylococcus hominis
;
enzymology
;
Temperature
6.Joinpoint regression analysis for the mortality trend of breast cancer in Chinese female from 1987 to 2014
Wei ZHOU ; Zhijiang ZHANG ; Yongyi BI ; Lijun WANG ; Xiaoxue LIU ; Chuanhua YU
Journal of Central South University(Medical Sciences) 2018;43(2):210-215
Objective:To analyze the current situation for the mortality of Chinese female breast cancer and the trend of change in the past thirty years,and to provide scientific basis for prevention and control of breast cancer in China.Methods:The mortality data of breast cancer in Chinese female from 1987 to 2014 were collected,the trends of age-standardized rates and age-adjusted rates were described,and the variations via Joinpoint regression models were analyzed.Results:From 1987 to 2014,the mortality for the urban female breast cancer was greater than that for the rural females.There was a downward trend for urban women with an average decrease of 0.3% for each year (P=0.06).While the average annual change for rural females showed an upward trend (AAPC=l.26%,P<0.01).The gap between urban and rural females is narrowing gradually.The 40-59 age-adjusted rate for urban females decreased first and then it was increased with time moving forward.The mortality for rural females was continuously increased.Conclusion:From 1987 to 2014,the breast cancer mortality for urban females was overall higher than that for rural females.The mortality for rural females was continuously increased in the past years.The gap between urban and rural females is narrowing.We should pay specific attention to the prevention and treatment of breast cancer for the rural females.