Objective: To observe the therapeutic effect of acupuncture plus rehabilitation on hemiplegia following stroke. Methods: Ninety-six patients with hemiplegia due to stroke were randomly allocated into two groups. The treatment group (50 cases) was treated with acupuncture plus rehabilitation, and the control group (46 cases) was treated with rehabilitation. Results: The total effective rate was 92.0% in the treatment group and 76.1% in the control group. There was a statistical difference in the effects between the two groups (P<0.05). Conclusion: Acupuncture plus rehabilitation is a perfect method for hemiplegia following stroke. It is especially effective in improving the function of limbs, relieving the spasm and improving the activity of daily life.