1.Therapeutic Observation of Micro-invasive Point-toward-point Thread-embedding for Post-stroke Shoulder-hand Syndrome
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):515-517
Objective To observe the clinical efficacy of micro-invasive point-through-point thread-embedding in treating acute stage of post-stroke shoulder-hand syndrome. Method Sixty patients were randomized into a treatment group and a control group, 30 in each group. Patients in the treatment group were intervened by micro-invasive point-through-point thread-embedding in addition to rehabilitation training, while patients in the control group were by rehabilitation training alone. Before treatment and after 4-week treatments, Visual Analogue Scale (VAS) was used to estimate shoulder pain, modified Barthel Index (MBI) to detect the activities of daily life, and Fugl-Meyer Assessment Scale to measure the motor function of upper limb. Result Before treatment, there were no significant differences in comparing the involved indexes between the two groups (P>0.05), and the indexes were significantly improved after intervention in both groups (P<0.05). Conclusion Micro-invasive point-through-point thread-embedding can reduce pain intensity, improve the activities of daily life and motor function of upper limb of patients in acute stage of post-stroke shoulder-hand syndrome.
2.Clinical investigation on relationship among lipoprotein(a) ,cerebral infarction and carotid atherosclerosis
Bin SHEN ; Chuan YU ; Dongyu WANG
Chinese Journal of Primary Medicine and Pharmacy 2015;22(1):48-50
Objective To investigate the correlation among Lp (a),cerebral infarction and carotid atherosclerosis.Methods 180 cases were equally divided into 3 groups (60 cases in each group).The patients with both cerebral infarction and carotid atherosclerosis composed one group(cerebral infarction group for short) ;the patients of carotid atherosclerosis which without cerebral infarction composed another group(no cerebral infarction group for short) ;the control group composed with those who had neither cerebral infarction nor carotid atherosclerosis.The level,outlier detection rate about Lp(a) and usual risk factors of cerebral infarction were compared in this research.Results The level and detection rate of Lp(a) in the cerebral infarction group were (512 ± 156) mg/L and 46.7% ;the level and detection rate of Lp(a) in the no cerebral infarction group were (316 ± 87)mg/L and 20.0% ;the level and detection rate of Lp(a) in the control group were (199 ± 123) mg/L and 5.0%.The differences of the level and outlier detection rate of Lp(a) among the three group were significant(F=13.87,x2 =29.394,P <0.01).Cerebral infarction patients had more usual risk factors of cerebral infarction (hypertension,diabetes,hyperlipemia,drinking,smoking,obesity and lack of exercise) than those who without cerebral infarction (x2 =15.523,P < 0.01).Conclusion The abnormal of Lp(a) was an important risk factor of cerebral infarction.The general survey of Lp(a) was significant in the primary and secondary prevention of stroke.To the people whose assay of Lp(a) was abnormal,the control of governable risk factors of cerebral infarction should actively be carried out.
3.Effect of Different Needle-retaining Lengths on the Therapeutic Efficacy of Acupuncture in Treating Post-stroke Shoulder Pain
Chuan YU ; Bin SHEN ; Shiwen XU
Shanghai Journal of Acupuncture and Moxibustion 2016;35(8):939-941
ObjectiveTo observe the effect of different needle-retaining lengths on the clinical efficacy of acupuncture in treating post-stroke shoulder pain.MethodSixty patients were randomized into a 30 min group and a 60 min group, 30 cases in each group. The same acupuncture treatment protocol was adopted in the two groups, and the acupuncture treatment was given once a day, 5 sessions a week, for 20 times in total. The Visual Analogue Scale (VAS), shoulder pain frequency, and Fugl-Meyer Assessment (FMA) were observed before treatment and after 4-week treatment.ResultThe scores of each index were significantly improved in both groups after treatment (P<0.01), and there were significant differences in comparing each index score between the two groups after treatment (P<0.05,P<0.01).ConclusionIn the treatment of post-stroke shoulder pain with acupuncture, 30 min needle-retaining is better than 60 min in comparing the analgesic effect.
4.Systematic Review of Acupuncture-moxibustion for Deglutition Disorders after Cerebral Stroke
Chuan YU ; Bin SHEN ; Shiwen XU
Shanghai Journal of Acupuncture and Moxibustion 2016;35(9):1126-1129
Objective To evaluate the clinical efficacy of acupuncture-moxibustion in treating deglutition disorders after cerebral stroke.Method By computer and manual literature retrieval, eligible randomized controlled trials (RCTs) were collected for systematic review by using the Cochrane method, and the meta analysis was performed by using Revman 5.2.Result Nine studies were recruited, covering 577 subjects of deglutition disorders due to cerebral stroke. The total effective rate of the treatment group was significantly higher than that of the control group [RR=0.36, 95%CI (0.25,0.50), Z=5.80 (P<0.00001)]. The treatment group was superior to the control group in improving the water drinking test (χ2=108.73,P<0.00001).Conclusion Acupuncture can produce a content therapeutic efficacy in treating deglutition disorders due to cerebral stroke, which still requires high-quality large-sample-size clinical RCTs for further verification.
5.Drawing up a Job Self-regulation Questionnaire for Airline Pilots
Space Medicine & Medical Engineering 2006;0(03):-
Objective To draw up a job self-regulation questionnaire for airline pilots and to evaluate its reliabilities and validities.Methods A job self-regulation questionnaire was developed based on documents and interviews.In order to examine the validity,208 airline pilots of CAAC were tested and 31 department leaders of them were interviewed.Results The self-regulation of airline pilot was composed of eight key dimensions,which had been examined in the confirmatory factor analysis.The Cronbach of full questionnaire was ?=0.743,and the reliability of each dimension was beyond Cronbach ?=0.516.Coefficient of stability of the questionnaire was beyond 0.606(P
6.Distribution of Blood Pressure in 7 936 Children and Adolescents in Guiyang and Analysis of the Associated Factors
xiang-yang, PENG ; yu-chuan, WANG
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To investigate the distribution of blood pressure and incidence of hypertension in children and adolescents from the urban area of Guiyang city aged 8-17 years old,in order to provide scientific evidence for preventing hypertension.Methods Seven thousand nine hundred and sixty-three primary and secondary students were sampled and standardized in blood pressure,height and weight.In accordance with the Working Group on Obesity in China(WGOC)recommendations,the subjects were divided into overweight,obesity and normal weight group,then the relationship between blood pressure and body mass index(BMI)and the prevalence of hypertension in different BMI groups were analyzed.Results 1.Compared with the USA and Shanghai city,the distribution of blood pressure in children and adolescents from the urban area of Guiyang city were different(Pa
8.Limb-shaking transient ischemic attack responsive to nimodipine: A case report
Liang-Yong Li ; Chuan-Yong Yu ; Lin Huang ; Yu Wang
Neurology Asia 2012;17(4):353-356
Limb-shaking transient ischemic attack (TIA), a rare manifestation, is commonly caused by severe
stenosis or occlusion of an extracranial internal carotid artery. Such patients are usually treated with
surgical revascularization or anti-platelet therapy. We present a 56-year-old woman with 6 months’
episodic attacks starting with mouth skewed to the right and a sensation of ‘weakness’ involving
predominantly her left arm, and at times, also involved the left leg. This was immediately followed by
rhythmic jerky movements of the left arm and at times, also involved the left leg. Magnetic resonance
angiography revealed severe stenosis of M1 segment of the right middle cerebral artery. The patient’s
symptoms were signifi cantly improved by treatment with anti-platelet drugs and nimodipine.
9.Value assignment study on bioactivity of monoclonal antibody working reference standard
Chuan-fei YU ; Chun-yu LIU ; Lan WANG
Acta Pharmaceutica Sinica 2021;56(2):565-569
The bioactivity of a working reference standard was determined by replicate bioassays with calibration against a primary reference standard. In this study the number of bioassay replicates needed for calibration first was calculated theoretically, and if the mean value of the experimental bioassay replicates fell within the predefined bioactivity level the bioactivity of the working reference was defined as 100%. Our results showed that when the total intermediate precision of the bioassay method was at 11.66% and the predefined bioactivity level was set at 95%-105% with a confidence level of 95%, 21 bioassay replicates should be carried out for calibration. The average value of the 22 experimental bioassay replicates was 101.96%, so the bioactivity of the working reference standard was consistent with that of the primary reference standard at 100%. The results suggest that a strategy of first calculating the number of bioassay replicates needed for calibration and then determining whether the resulting experimental mean value is within the predefined bioactivity level will be of value to the biopharmaceutical industry.
10.Exhaled nitric oxide in asthma.
Yu MA ; Chuan-he LIU ; Gary W K WONG
Chinese Journal of Pediatrics 2005;43(6):421-422