No abstract available.
Ring Chromosomes*

Nuciferin, a chemical extracted from the leaves of Nelumbo nucifera Gaerth. Chromosome mutagenicity of nuciferin was evaluated in bone marrow cells and testicular cells of 30 mice. Chromosome preparation were sampled 24h after injection of nuciferin. 2880 metaphases from bone marrow cells and 2720 metaphases diakinesis from testicular cells were analyzed. The frequency of cells with numerical and structural chromosome aberrations of treated mice showed no significant difference than that found in the control. The result obtained on the study suggested that nuciferin did not exert any chromosome mutagenicity.
Aporphines ; Chromosomes

No abstract available.
Congenital Abnormalities* ; Ring Chromosomes*

Background: Normally, gender of human is indentified according to enternal sexual organ. However in several cases the patient\u2019s gender is not able to identify based on enternal sexual organ. In these cases test for gender identification is need. Objectives: Identify relationship between clinical condition of the external sexual organ and sexual chromosome. Subjects and method: 119 patients with diagnosis of \u201cunclear gender identification\ufffd?made by hospitals in Ha noi. Culture of peripheral blood, analyze sexual chromosome, comparing with gender indentification proposed in neonatal period and gender indentified by physical at time of examination. Results: 87/119 cases (73,11%) have male sexual chromosome. According of gender proposed in neonatal period to sexual chromosome are 76,90% for children considered \u201cboy\ufffd?and only 33,33% for \u201cgirl\ufffd? The according percentage is higher at time of examination (mean age is 6,4 years old). There are 4 cases of female phenotype with XY sexual chromosome. Conclusion: In cases with unclear gender identification in neonatal period: 73,11% cases have male sexual chromosome (XY). Apprasal gender at neonatal period is difficulty accurate, especialy for children considered girl (the according rate is only 33,33%). \ufffd?Detect 4 cases of \u201ctesticular femiuization\ufffd?
Sex Chromosomes ; Gender Identity ;

Chromosome analysis in bone marrow of leukemia patients and comparison of abnormalities between leukemia types classified by immunology using monoclonal antibodies showed that: There are chromosome abnormalities in 42 among 64 myeloid leukemia patients. Usual abnormalities are +8, t(8q; 21q+), t(15q+;17q-). In 17 lymphoblastic leukemia patients, there are 10 cases having chromosome abnormalities, the most frequent is t(9q+; 22q-). An acquired abnormalities (der 11q) added on constitutional abnormalities rob (14; 21) was detected in a myeloid leukemia patient
Leukemia ; immunology ; Chromosomes

19 children at the age from 2 days to 15 years old includes: 15 females, 3 males and 1 hermaphrodite: - The clinical examinations, health records, analysis of chromosomes and dermatoglyphics shown that : In 5 cases with chromosomal aberrations: + 3 cases down (2: trisomi 21 and 1 down translocation D/G) + 1 case with symtoms of male turn (chromosome Y chromosome F)+1 case hermaphrodite, karyotyp 46, XY, with muti- malformations and female phenotype. -The analysis of acrocentric- chromonomal association shown that: +Frequency of acrocentric- chromosomal associations: 62% + Frequency of acrocentric- chromosomal associations per cell: 1.18. + The means of chromosomal association: 2.13. +Frequencies of gaps, isogaps, chromosomal aberrations, chromatid aberrations are the same in comparision with the other researchers. + In all of three patients with limb malformations, there are abnormalities in dermatoglyphics
Congenital ; Chromosomes ; Dermatoglyphics

20 patients with primitive polycythaemia, aged > 16 were studied at The Central Instutitute of Hematology and Blood Transfusion from August 2000 to July 2001. Patients underwent clinical examinations, specialized test and spinal fluid culture. On 15 of 20 patients, karyotype was specified no abnormality was detected in terms of chromosome number, there are 3 cases of chromosomal morphologic disturbances were considered evidence of hyper trophic characteristics of cloning process us of primitive polycythemia.
Chromosomes ; Polycythemia ; Diagnosis

Chromosomes of 45 samples of fetal monkey kidney cells from primitive to 9th passages was examined. Results showed the quantity of 2n = 42 chromosome reached 89,86-96%. The polyploidy phenomenon including internal polyploidy trended to increase from the 4th passage and the most number of chromosomes was obtained from 6th to 9th passage. In every passage, both numeral mutation and aberration were at normal range
Chromosomes ; cells ; Haplorhini ; Kidney

Investigating the influence of trifluoromethylhydroartemisinin (BB.101) on chromosome mutations of mice. Mices were divided into 4 batches (B1, B2, B3 were dosed with BB.101 50mg/kg/day x 5 days, once, twice and thrice, respectively; each treatment course was repeated with 7 days intervals. B4 (control) were tested with arabic gum emulsion 1%). The results showed that: BB.101 were found not to increase frequency of confused chromosome in bone marrow cells of mices. Cells with confused structures and trouble clusters as crushed and smudged chromosomes were not found. BB.101 with the same dose was found not to increase frequency of confused chromosome in testicle cells of mices
Chromosomes ; Mice ; artemisinins

Chromosomes, Human, Pair 14 ; Humans ; Ring Chromosomes ; Syndrome