1.Comparison of Cardiovascular Responses between Remifentanil and Fentanyl on Laryngoscopy and Tracheal Intubation in Patients Undergoing Elective Surgery
Journal of Surgical Academia 2014;4(1):20-25
This was a prospective, randomized, double-blind study comparing the effect of remifentanil and fentanyl on
cardiovascular responses from laryngoscopy and tracheal intubation. Forty-four ASA I or II patients aged between
18-65 yrs scheduled for elective surgery under general anaesthesia, were recruited and randomized into two groups.
Each patient in Group R received remifentanil of 0.5 mcg/kg bolus over 30 seconds followed by an infusion of 0.25
mcg/kg/min and each patient in Group F received fentanyl of 2 mcg/kg bolus over 30 seconds followed by an
infusion of normal saline. Anaesthesia was then induced with propofol, rocuronium and 2% sevoflurane with 100%
oxygen. Cardiovascular changes were recorded every minute for 3 minutes after induction and 5 minutes after
tracheal intubation. The heart rate remained stable throughout the induction and intubation period in both groups.
None of the patients in the remifentanil group develop bradycardia. Systolic blood pressure (SBP) and mean arterial
pressure (MAP) were significantly lower in the fentanyl group at the 3rd minute post-induction and 5th minute postintubation
(p < 0.05). Diastolic blood pressure (DBP) in the fentanyl group was significantly lower at the 2nd and
3rd minute post-induction and 4th and 5th minute post-intubation (p < 0.05). The blood pressure remained stable for
the remifentanil group throughout the induction and intubation period. Six patients (27.2%) in the fentanyl group and
one patient (4.5%) in the remifentanil group experienced hypertension. Three patients (13.7%) from each group
experienced hypotensive episodes. In conclusion, remifentanil 0.5 mcg/kg bolus followed by 0.25 mcg/kg/min
infusion resulted in SBP, MAP and DBP remained slightly lower than baseline throughout the whole period but still
consider stable, as these changes were not statistically significant.
Keywords: Cardiovascular; remifentanil; fentanyl; laryngoscopy; anaesthesia
2.Survey of Nurses’ Knowledge and Attitude Regarding Post Operative Pain Management at a Teaching Hospital in Malaysia
Ho SE ; Choy YC ; Rozainiee A
Medicine and Health 2009;4(1):47-52
Post operative pain is an expected adverse outcome following surgery and it often delays mobilization and overall recovery. Acute post operative pain is subjective and cannot be measured directly. The objective of this study was to determine nurses’ knowledge and attitude towards post operative pain management. A cross sectional study was conducted in surgical wards and the Intensive Care Unit of Universiti Kebangsaan Malaysia Medical Centre from February to April 2008. A 28 item questionnaire which comprised of two domains: knowledge and attitude towards post operative pain management was used. Eighty four respondents successfully responded to the study. Twenty respondents (25%) possessed high level, 58 respondents (69%) possessed moderate level and 5 respondents (6%) had low knowledge level of post operative pain management. Positive attitude towards post operative pain management was reported by 66 respondents (78.5%). There was a significant relationship between nurses’ academic qualifications and attitude towards post operative pain management (χ² =29.96, p <0.05). In conclusion, nurses in UKMMC possessed moderate level of knowledge and positive attitude towards post operative management. Results of this study show the need to enforce continuing medical education in pain management amongst UKMMC nurses in enhancing the quality of post operative care.
3.Information Needs of Post Myocardial Infarction (MI) Patients: Nurse’s Perception in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
Ho SE ; Hayati Y ; Ting CK ; Oteh M ; Choy YC
Medicine and Health 2008;3(2):281-287
Patient education has been considered as an integral component of care for patient after myocardial infarction. Post myocardial infarction patients require information and knowledge related to their conditions to reduce anxiety and aid recovery. The objective of this study was to identify nurses’ perception on information needs of post MI patients of UKMMC. A cross sectional study using Cardiac Patient Learning Needs Inventory (CPLNI) adopted from Timmins and Kalizer (2002) was used. It comprises seven cate-gories: related to anatomy and physiology, psychological factor, life style factor, medi-cation information, dietary information, physical activity, and symptom management. This study was conducted in coronary care unit (CCU), coronary rehabilitation ward (CRW), medical ward 1 and medical ward 2 from January 2007 to March 2007. 56 res-pondents (96%) who fulfilled the inclusion criteria were recruited in this study. Results showed that CCU and CRW respondents ranked symptom management as their first ranking followed by medication, life style factor, anatomy and physiology, dietary in-formation, physical activity and psychological factor. However, respondents in Medical Ward 1 and 2 reported and ranked medication information as their top priorities fol-lowed by symptom management, psychological factors, dietary information, physical activity, anatomy and physiology and life style factor. There were significant differ-ences between ward nurses’ responses with their perception related to anatomy and physiology, psychology factor, life style factor, physical activity, and symptom man-agement with p value<0.05. This study concluded that the information needs are not always perceived in unison by nursing personnel as the CCU and CRW nurses ranked symptoms management as the cardinal factor whilst Medical Ward 1 and 2 nurses give paramount importance to medication. In order to improve this situation for post MI pa-tient, information need has to be tailored, individualized and prioritized based upon their needs.
4.Structured Education Programme on Patient Controlled Analgesia (PCA) for Orthopaedic Patients
Ho Se ; Christopher Ck HO ; Zainah M ; Indra ; Jaafar MZ ; Choy YC ; Ismail MS
Medicine and Health 2016;11(1):62-71
Patient-controlled analgesia (PCA) via an infusion pump enables patient to
administer their own analgesia. The aim of this study was to evaluate the effect
of an educational programme in managing post-operative pain and satisfaction
on PCA following orthopedic surgery. A pre-test and post-test interventional study
design with implementation of patient education programme on PCA was provided
to 54 respondents. The control group received conventional PCA briefing from
the Acute Pain Service protocol. Pain intensity was measured at 2 hrs, 6 hrs and
24 hrs following surgery and pre-test and post-test of the Revised American Pain
Society Patient Outcome Questionnaire (APS-POQ-R) was administered. There
was difference in respondents’ level of pain score among the study respondents’
medians for control group at 2 hrs, 6 hrs and 24 hrs following surgery and they were
7.00 (IQR=3.00), 5.00 (IQR=2.00) and 3.00 (IQR=2.00); intervention group at 2 hrs,
6 hrs and 24 hrs following surgery were 6.00 (IQR=2.00), 3.00 (IQR=1.00) and
1.00 (IQR=1.00) respectively. There were significant differences in median of pain
score between intervention and control group at 2 (U=142.0, p<0.05), 6 (U=150.50,
p<0.05) and 24 (U=120.00, p<0.05) hrs following surgery. There were statistically
significant differences (p<0.05) in the median of patient’s pain severity at all pain
levels i.e. least pain, worst pain, and severe pain between intervention and control
group (least pain, U=219.50, p<0.05; worst pain, U=117.0, p<0.05; severe pain,
U=49.0, p<0.05). In conclusion, patients who received pre-operative structured
education programme showed improvement in managing post-operative pain and
satisfaction on PCA after orthopedic surgery.
Analgesia, Patient-Controlled
5.Case Study on the Effect of Epidural Analgesia on Pain Management During Labour
Ho SE ; Sumathi U ; Ismail MS ; Choy YC ; Ahmad Zailani H ; Liu CY
Medicine and Health 2013;8(1):33-36
Child birth is associated with severely painful experience for the parturient, and often exceeds one’s expectations. Even though, severe pain is non life-threatening condition in healthy parturient women, it may lead to undesired neuropsychological consequences. When no analgesia was used, postnatal depression may be more common, and this labour pain leads to the development of post-traumatic stress disorder. Epidural analgesia is now considered gold standard for effective pain relief during labour. We here report a case of a 37-year-old G1 P0 patient at term gestation who successfully used epidural analgesia for labour pain management.
6.Quality Of Life amongst Post Coronary Artery Bypass Patients at the National Heart Institute, Malaysia
Ho SE ; Noor Siah AA ; Zaidah Z ; Teoh KH ; Gurbinder JS ; Ismail MS ; Choy YC ; Mazeni A
Medicine and Health 2010;5(2):77-85
Coronary Artery Bypass Grafting (CABG) surgery has increased the survival rate for individuals suffering from myocardial infarction or coronary ischemia. The present
study aimed to examine the perception of quality of life amongst post CABG patients at the National Heart Institute Malaysia. A total of 69 post CABG patients, were studied
using the Medical Outcomes Short Form 36 (SF-36). The findings showed that post CABG respondents possessed good level of quality of life (SF-36) physically and
mentally. There were significant differences between the role physical in the physical functioning domains of quality of life with gender (t=0.286, p<0.05). Duration of physical exercises of more than 20 minutes have positive effects on both physical (t=2.738, p<0.05) and mental components (t=7.326, p<0.05). The level of income influenced both the physical component (F=3.100, p<0.05), and mental component (F=4.272, p<0.05). Post CABG patients were found to have high quality of life post operatively.
They were able to make comprehensive lifestyle changes through frequent physical exercises to accommodate their needs.
7.The Impact of a Patient Education Package on Outcomes of Pain Management Following Orthopaedic Surgery in a Tertiary Hospital in Malaysia
Ho SE ; Wan Ahmad L ; Christopher CK Ho ; Tan ZY ; NurSharifah MS ; Choy YC ; Jaafar MZ ; Sabarul AM ; Sharaf I
Medicine and Health 2015;10(1):58-65
Patient’s belief towards pain management may affect pain management outcomes
and quality of life. The main aim of the present study was to determine the impact
of a pre-operative pain education package towards pain belief among patients
undergoing orthopaedic surgery in a tertiary hospital. A one-group pre-test post-test
design study was conducted on orthopaedic surgery patients. Thirty respondents
were recruited and pre-operative pain education was administered individually
before surgery. Pre-operative and post-operative pain belief, management scores
and side effects were measured using the Barrier Questionnaire (BQ-13). The results
reported significant differences between pre-test scores (Mean = 41.87, Standard
Deviation = 11.467) and post-test scores (Mean=34.80, Standard Deviation=13.026)
of pain belief (t = 2.84, p = 0.004). There were also significant differences between
pre-test scores (Mean = 37.10, Standard Deviation = 10.610) and post-test scores
(Mean=30.80, Standard Deviation = 11.424) of pain management (t = 3.856, p
= 0.0005). Respondent’s gender (t = -2.403, p = 0.023) and ethnicity (F = 5.038,
p=0.014) reported significant differences with p value < 0.05, respectively. However,
there were no significant differences between educational level, ethnicity, prior
surgical history with pain belief (p> 0.05). There was positive impact of the pain
education package towards pain belief and painmanagement among respondents
who underwent orthopaedics surgery in a tertiary hospital. Reinforcement of pain
educational program is pivotal in order to achieve optimal post-operative pain
management.
Pain management
8.Patient-Related Barriers to Cancer Pain Management – A Prospective Cross Sectional Study in a Tertiary Hospital
Choy YC ; Wan Nuruddin Shah WJ ; Wong YM ; Boey CY ; Noor Zuhaily MN ; Kumutha T ; Juliana J
Journal of Surgical Academia 2013;3(1):7-12
Effective management of cancer pain is often hampered by patients’ lack of knowledge regarding cancer pain
management and other barriers related to ethnicity and religious beliefs. This cross sectional study was
performed to determine the patient-related barriers to effective cancer pain management. One hundred patients
receiving cancer pain management were studied. Inclusion criteria were: patients over the age of 18 years, able
to communicate, with known diagnosis of cancer, experiencing persistent pain for the past two weeks. A
modified version of the Barriers Questionnaire II (BQ-II) was used and a modified Brief Pain Inventory was
used to assess the pain profile. Barriers such as, patient’s attitude and beliefs, communication skills and fear of
side effects of pain medication were determined, given a score and the summation was recorded as the total
patient related barriers score. Overall, 85% of respondents achieved more than 40% pain relief and the 72 of 100
patients reported low patient related barrier scores of 6 or less. Nevertheless, the main patient related barriers
were: fear of tolerance to opioids (51%), ethnicity (p=0.003) and religious beliefs (p=0.002) which constituted
the major components of the patient-related barriers score. Ethnicity and religious beliefs had significant
influence on patient-related barriers score suggesting the need of further investigation into this area. In order to
achieve a comprehensive view, other barriers to effective cancer pain management such as those related to the
health systems and healthcare providers need to be assessed together.
9.Attitude of Patients towards Anaesthesia: Comparing the Use of a Single Consent for Anaesthesia versus the Combined Surgical and Anaesthetic Consent
Niew YL ; Magdalene Chee MX ; Juanita J ; Nurul Ezzati AK ; Mohd Sharol AW ; Azarinah I ; Choy YC
Journal of Surgical Academia 2014;4(2):9-13
Anaesthesiology is a specialty which is less well known and the public usually have little knowledge regarding
anaesthesia and the roles of Anaesthesiologist. Many hospitals now use a single dedicated consent for anaesthesia.
This study was conducted to compare the effectiveness of a single consent for anaesthesia with the combined
surgical and anaesthetic consent. A total of 109 patients, scheduled for elective surgery requiring anaesthesia were
interviewed with a standardised questionnaire. Patients were divided into two groups, where one group used a single
anaesthetic consent while the other used a combined surgical and anaesthetic consent. A single consent for
anaesthesia was found to be more effective than the current combined surgical and anaesthetic consent (p<0.05).
Regarding information about anaesthesia, 89.91% respondents agreed that the Anaesthesiologist should tell them all
material risks of anaesthesia, no matter how serious it is and 81.65% respondents would like to meet
Anaesthesiologist every time prior to the operation. In terms of knowledge, 94.5% patients recognized that
Anaesthesiologist is the one who delivers anaesthesia during surgery. However, patients had little knowledge
regarding the extended roles of Anaesthesiologist. The present study confirmed that a single consent for anaesthesia
was better than the current combined surgical and anaesthetic consent.