Objective]To explore the essence of doubts differentiation from‘Neiwaishangbianhuolun’,the monumental work of the medical practitioner Dongyuan Li in Jin and Yuan Dynasties, and relativity between internal damage and exogenous diseases.[Methods] By means of researching the background of‘Neiwaishangbianhuolun’, analyzing the 13 main differentiations, think about the essence of doubts differentiation; meanwhile, by connecting to the explicate of mechanism of ascending yangqi belonging to exterior-releasing medicine(wind-expel ing drugs) in his representative work‘Piweilun’, discuss the contrary and transforming relationships between exogenous wind-cold and internal damage of the stomach and spleen, comparing to academic thoughts of Zhongjing Zhang’s‘Shanghanlun’. [Results]Realize essence of doubts differentiation from ‘Neiwaishangbianhuolun’ is not exterior or interior of disease location,but deficiency and excess of disease character.By analyzing the functional mechanism of wind-expel ing drugs and relationship among exogenous diseases,wind-expel ing drugs and the stomach and spleen, raise the relativity between internal damage and exogenous diseases. [Conclusions] The revealing of the essence of deficiency and excess differentiations from‘Neiwaishangbianhuolun’, together with knowledge of the functional essence of wind-expel ing drugs and the relevance of internal damage and exogenous diseases, may open the mind partly for syndrome differentiation and medications in the clinic.

Rhubarb has a bitter taste and a cold nature.It is known for its functions of clearing heat and detoxifying,cooling blood and purging fire,stopping bleeding and promoting blood circulation,eliminating blood stasis,and dredging the channel.Mou Yunfang believed that the use of Rhubarb belongs to the"purgative"method of the 8 traditional Chinese medicine(TCM)methods,but it was not simply used for defecation.In fact,it was an act of expelling evil spirits.The evil spirits of heat release,turbidity,blood stasis,toxin,and phlegm are eliminated from the intestinal and visceral gates.With proper clinical application,it can save the suffering in an instant.And 5 proven cases of sepsis,fracture pain,cholelithiasis,pregnancy with intestinal abscess and exogenous fever were selected to analyze his clinical experience in using Rhubarb.The effect of using Rhubarb to cool blood and relieve heat in sepsis of internal medicine.Traumatology fractures have the function of promoting blood stasis,promoting blood circulation,and relieving pain.Although surgical cholelithiasis treats the gallbladder,it is effective through the use of Rhubarb to attack the accumulation of organs,promote dampness and reduce jaundice.Although gynecological pregnancy with intestinal abscess should not be attacked severely,Rhubarb should still be used to relieve dampness and heat in the intestines and remove blood stasis in the intestines,which is known as the"combat severe disease with drastic medicines"principle;pediatric fever caused by external factors,wind cold and internal dampness entrapment.When dispelling cold and dampness,a small amount of Rhubarb should be used to relieve constipation,providing a way out for evil and resolving both the exterior and interior.Grandmaster believes that the clinical use of Rhubarb has a wide range of indications,such as acute abdomen,chronic obstructive pulmonary disease,liver cirrhosis,stroke,myocardial infarction,rabies,tetanus,venomous snake bites,and many other difficult and miscellaneous diseases.However,the principle of differentiation and treatment still needs to be followed,and the pathogenesis of"stomach excess",that is,the heat syndrome of the internal excess,should be closely grasped in order to be effective.If it is a deficiency syndrome,it should be avoided.