Studies of life quality as a sociological indicator originated in the U.S. in the 30s of the 20 th century. With the change of the disease spectrum and the medical model, the implication of the concept of health has been expanded. Towards the end of the 70s, life quality studies started in the medical field and gradually flourished, resulting in the development of hundreds of measured quantity tables. The deepening of such studies has brought about increasingly bigger effects on modern medical sciences. These effects can be seen in the following aspects: ①changes of medical thinking, objective and concepts; ②patients*s participation in the choice of their treatment plans; ③new medical treatment and nursing regulations; ④the making of medical administration and health decisions; ⑤development of new drugs, which must take into consideration effects on life quality; and ⑥management of medical records.

Objective: To develop a general module of self-administered quality of life instrument for Chinese patients with chronic disease. Methods: Using the structured group (nominal group and focus group) methods and the qualitative and quantitative theory and methodology in developing rating scales Items were preliminary screened, evaluated and modified, and the QoL data measuring from 201 cases of patients of 8 different chronic diseases were analyzed by the methods of coefficient of variation?factor analysis, clustering analysis and correlation analysis. Result: General module of quality of life instrument for patients with chronic disease (QLICD-GM) was developed and evaluated. It consists of three domains: physical function, psychological function and social function, 32 items. Conclusions: QLICD-GM possessed a reasonable good content validity for it reflect WHO 's definition and connotation of QoL, and also common issues of patients with chronic disease.

Objective: To revise and evaluate the Chinese version of the FACT-B. Method: The Chinese version of the FACT-B was translated from the original one, after back-translated and culture adaptation, it was applied to 165 patients with breast cancer. Result: The test-retest reliability of five domains, such as physical well-being, social/family well-being, emotional well-being, functional well-being, additional concerns and the overall scale were 0.82～0.89. The internal consistency alpha for the five domains were 0.61～0.84. After admission to hospital 2-4 weeks, the quality of life of patients showed some change in this scale. Conclusion: The Chinese version of the FACT-B has good psychometric quality and can be used to assess the quality of life of Chinese patients with breast cancer.

ObjectiveTo study the relationship between subjective well-being and family care degree of medical college students.Methods2695 medical college students were tested by Family APGAR index and Oxford Happiness Test-Revised.The data was analyzed by independent-sample t test,pearson correlations and linear regression.Results ( 1 ) The subjective well-being and family care degree and its factors of college students were above average.The score of subjective well-being was 43.08 ± 11.16,and the score of family care degree was 6.48 ±2.39.(2)The family care degree( t=3.462,P＜0.01) and its adaptation( t=2.718,P＜0.01),partnership( t =4.178,P＜0.01),and growth( t=4.484,P＜0.01 ) of female students were higher than male students.The family care degree ( t =3.939,P ＜ 0.01 )and its adaptation ( t =4.683,P ＜ 0.01 ),partner-ship ( t =3.306,P＜ 0.01 ),and growth ( t =2.796,P ＜ 0.01 ) and subjective well-being( t =3.508,P＜ 0.01 ) of the students who came from cities and towns were higher than the students who came from rural.(3)There was a significant relation between subjective well-being and family care degree and its factors( r=0.197 ～ 0.357,all P＜0.05 ).The partner-ship,resolve,growth and affection can forecast together the 13.2％ variance of subjective well-being.ConclusionEnhancing family care degree is contribute to the subjective well-being and psychological health of medical college students.

Objective To develop the specific module of quality of life instrument for patients with esophageal cancer. Methods with the structured group ( nominal group and focus group) methods and the qualitative and quantitative theory and methodology in developing rating scales, items were preliminary screened, evaluated and modified. And the data measuring from 28 cases of esophageal cancer patients and 25 doctors/nurses were analyzed by 4 statistical procedures: method of coefficient of variation, correlation analysis, patients'importance rating procedure and doctors' importance rating procedure. Results By above statistical procedures and advises of doctors, thus 19 - items specific module was formed finally. Conclusions The specific module developed on the strict procedures has good content representativeness and validity.

Objective To analyze the disease burden of Yi nationality.Methods Disability adjusted life years(DALY) was used as the measurement indicator of disease burden.Results The male had greater Years of Life Lost to Premature Death(YLL)per thousand populations,Years of Lived with Disability(YLD) and DALY than did the female almost in each age group.The burden of Neuropsychiatric conditions was the heaviest.The burden of Yi nationality was heavier than Han nationality in diseases during perinatal period and digestive diseases.However,the disease burden of malignant neoplasm of Han nationality was heavier than Yi nationality.Conclusion The prevention and treatment of neuropsychiatric conditions,diseases during perinatal period and digestive diseases should be enhanced in Yi nationality.

Objective To analyze the quality of life and its influence factors in patients with peptic ulcer.Methods The SF-36 was used to survery 120 patients with peptic ulcer.The QOL scores at different levels of some factors including gender,age,na-tionality,occupation,marriage,medical forms,economic,cultural level,treatment method and clinical type were compared by meth-ods of two sample t-test and analysis of variance.Results Peptic ulcer patients′scores in the domain of RE,PF,RP,BP,GH,VT, SF,RE,PCS and MCS are lower than that of the normal,exception of the domain of MH(P <0.05).The differences were statisti-cally significant.Six factors can be influenced some domain or total score of the scale(P <0.05)and the differences were statistical-ly significant.Conclusion Find out the influencing factors on peptic ulcer patients′quality of life can be provided the basis for clini-cal treatments.

Objective To develop and evaluate the Quality of Life Instruments for Chronic Diseases -Osteoarthritis ( QLICD-OA). Methods The QLICD-OA was evaluated by testing 140 in-patients with Osteoarthritis. The statistical methods used included correlation analysis, factor analysis, paired t test and Generalizability coefficient. Results The rest-retest reliability γ of QLICD-OA was 0.91, Cronbach’s α for overall scale was 0.98 and Generalizability coefficient was 0.94. Correlation and factor analysis demonstrated good construct validity. After treatment, statistically significant scores were found in the tested group for Specific module and total instrument. Conclusions The QLICD-OA has good validity, reliability and responsiveness. The QLICD-OA may serve as the QOL measurement scale for patients with Osteoarthritis in China.

ObjectiveTo analyze and evaluate the responsiveness and feasibility of the quality of life instrument for patients with systemic lupus erythematos(SLE).Methods143 cases of SLE patients were measured by QLICD-SLE before and after treatment and the data were analyzed with the traditional hypothesis test and combining the effect size,standardized response mean,the relative efficiency,the standard effect size and the feasibility analysis methods.Results(1)Paired t test before and after treatment indicated that there were significant differences between after treatment and before treatment in physical(t=2.39,P<0.05) and specific module domain(t=2.22,P<0.05),while there were no significant promotion in the scores of psychological function,social function and total score after treatment.There were no significant changes of SES,SRM and CR after treatment.(2)Most patients could understand the meaning of the instrument well and spent 15-20 minutes to finish it.The rate of recovery and completed were 98.0% and 97.8% respectively.ConclusionsThe QLICD-SLE can detect clinical change of treatment with good responsiveness and feasibility.

Objective To compare the quality of life ( QOL) in different family life cycle residents and analyze its influencing factors. Methods Based on the stratified cluster sampling,517 married residents from three communities of Dongguan city were chosen to be investigated by a questionnaire on the general status and the MOS health survey (SF-36).The One-Way ANOVA and Multiple Regression Analysis were used to analyze the data. Result There were significant differences on the seven domains of the SF-36 ex-cept of physical pain in different family life cycle residents (P<0.05) . The scores of different domains at the retirement or senior years were the lowest ( ranging from 37.10-59.81) ,and the scores of different domains at the child-bearing period were highest (ranging from 37.10-59.81). The results of Multiple Linear Stepwise Regression showed that the QOL of different family life cycle residents were influenced by some factors. The influencing factors on PCS at the child-bearing period were income (β=1.51) and life events (β=-6.13), while that at the period of families with adolescents were economic income (β=1.81) and age (β=-0.65);that at the period of empty nest were economic income (β=-3.64) and age (β=-0.65);and that at the re-tirement or senior years were unhealthy living habit (β=-15.06),age (β=-0.56) and income (β=3.06). The influencing factors on MCS at the child-bearing period was medical insurance (β=5.86),while that at the period of families with adolescents were medical insurance (β=6.28),education (β=2.32),life events (β=-4.68) and occupation (β=-5.53);that at the period of the empty nest were age (β=-0.61) ,gender (β=-10.35) and chronic disease (β=-8.35);that at the retirement or senior years were age (β=-0.27) , economic income (β=2.55) and unhealthy living habit (β=-6.95) . Conclusion The influencing factors of QOL for different family cycle residents are not conformity with each other. It suggested that in order to im-prove the QOL of residents, the community health service including health education and health promotion should be based on different family life cycle.