Introduction Along with the changes occurred in nutrition, climate over the years, the prevalence of blood disorder related diseases, such as Аllergic purpura (AP), Idiopathic thrombocytopenic purpura (ITP) is increasing. The current perspective of health service is focused on the treatment of AP and ITP by using combined therapeutic methods of modern and Mongolian medical approach. Mongolian traditional medicine has an advantage of reducing complications in reducing the recovery duration and also preventing from re-occurrence. Consequently, there is a need for investigation of formulating clinically effective preparation that complies with pharmaceutical standards. Objective The objective of this study was to develop the technology to obtain Tsusan Bolor capsules and establish its some quality criteria indicators. Materials and Methods The medicinal raw materials Gardenia Jasminoides Ellis, Rubia cordiofolia L, Picrorhiza serophulariflora Pennell, Arnebia guttatа, Crocus sativus, L, Pulvis Cornus Bubali and Artificial Bezoar were provided by Traditional medicine factory of the Inner Mongolian University for Nationalities, PRC. The L9(34) experiment test was used to obtain the extracts from crude medicinal plants and TLC, HPLS and pharmacopeias methods were used for the establishing quality criteria indicators of the capsules. Results Within the technological study the appropriate methods to obtain alcohol and water extracts from the medicinal raw materials and the technological scheme to obtain Tsusan bolor capsules were developed. As the results of quality criteria investigation indicated, the total content of gardenia glycoside is 1.71±0.02 mg, water content- 6.25±0.1%, heavy metal and arsenic content less than 10 μg/g and 2μg/g and disintegration time of the capsules is 20±3.

ABSTRACT. Recurrent aphthous stomatitis, or RAS, is common oral disorder of uncertain etiopathogenesis for which only symptomatic therapy is available. This article reviews the current clinical features of RAS among study patients and the result of therapeutic effects of the herbal preparation Akhizunber. Over the past four years we have treated 61 RAS patients with different clinical forms by herbal preparation Akhizunber or Alumekatin. The distribution of clinical forms RAS RAS among study patients were minor aphthae -75.4%, major aphthae -16.4% and herpetiform ulcers -8.2% respectively. The healing time of treated Akhizunber was in minor aphthae -9.28±4.82 days, major aphthae -14 days and herpetiform ulcers -12 days. Of the total study participants, the patients treated by Akhizunber reported a rapid and complete recovery from RAS during treatment compared with treated patients by Alumekatin. Treatment with herbal preparation Akhizunber can be effective for patients suffering from RAS in any clinic form, regardless of their ulcer number and size.