OBJECTIVE:To investigate the characteristics of adverse drug reactions(ADR) in our hospital so as to promote rational clinical drug use.METHODS:244 ADR cases collected in 2005 in our hospital were analyzed retrospectively.RESUL TS:Among the 244 cases,the female exceeded the male;79.83% of the patients were more than 40 years old.The cardiovascular system medicines took the lead which amounted to 45.69% of the total,then came the antimicrobial medicines.The intravenous administration caused most of ADRs.Alprostadil Injection accounted for 9.02% of the total, the highest.Skin and its appendages impairment cases took the biggest percentage at 28.14%.CONCLUSION:we should pay more attention to the ADR monitoring and the spread of ADR knowledge and enhance the ADR awareness of medical staff.sen or avoid the occurrence of ADR,monitoring of which and publicizing of ADR knowledge should be emphasized.