1.Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
Sherrini Bazir Ahmad ; Chin Sum Cheong ; Shen-Yang Lim ; Kartini Rahmat ; Faizatul Izza Rozalli ; Shamala Devi Sekaran ; Helmi Sulaiman, Sasheela Ponnampalavanar ; Kheng Seang Lim ; Chong Tin Tan
Neurology Asia 2016;21(4):375-379
There are 50-100 million dengue infections each year, but dengue encephalitis is relatively
uncommon. The aetiology of neuronal injury is proposed to be due to direct viral neurotropism or
host immune response-mediated inflammation causing neuronal damage. We report a case of severe
dengue encephalitis, presenting during the acute viraemic phase of the disease. This was associated
with inflammation and haemorrhage of the internal medullary lamina of both thalami which, to our
knowledge, has not yet been reported in other infections of the central nervous system.
Dengue
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