We reported two cases successfully treated with sano-to (Senkin-Ho). Case 1 was a 63-year old female, who visited our department in December 2004 complaining of polyarthralgia, a burning sensation in the hands and feet, irritability and chilliness. We prescribed sano-to (Senkin-Ho). The visual analogue scale (VAS) decreased from 100 mm on the first visit to 23 mm 10 months later in October 2005. Case 2 was a 62-year old female, who came to our department complaining of whole body pain in August 2004. Various Kampo medicines were tried but proved ineffective, and in June 2005 she was hospitalized. At that time, in addition to whole body pain, she complained of a burning sensation in her feet, psychological anxiety, and chillness. We prescribed sano-to (Senkin-Ho). After 2 months, her VAS decreased from 80 mm to 20 mm. We consider that sano-to (Senkin-Ho) should be prescribed more actively when patients suffer from painful diseases accompanied with subjective symptoms such as a burning sensation in the hands and feet, psychological symptoms, and chilliness.
Feet, unit of measurement ; Burning sensation ; Chills ; Cases ; symptoms <1>

Aerococcus viridans is a rare pathogen in humans, with only six cases of A. viridans urinary tract infections reported worldwide. Nosocomial urinary tract infections with bacteremia caused by A. viridians are even rarer, with no prior reports of urosepsis caused by A. viridans occurring in the Republic of Korea. Here we report a case of urosepsis caused by A. viridans in a 79 year-old female nursing home resident. The patient was admitted to the hospital presenting a fever of 39degrees C, chills, and oliguria for two days prior to admission. Urine culture yielded a robust growth of 105 CFU/mL of A. viridians, with blood culture positive for the same organism. Following diagnosis, the patient was treated with ciprofloxacin intravenously for 2 weeks, resulting in clearance of the infection and a full recovery from urosepsis. Although A. viridans is rarely associated with human infections, this case shows that, under the right conditions, it can be responsible for severe infections like urosepsis.
Aerococcus* ; Bacteremia ; Chills ; Ciprofloxacin ; Diagnosis ; Female ; Fever ; Humans ; Nursing Homes ; Oliguria ; Republic of Korea ; Urinary Tract Infections

Rituximab is a human/murine chimeric anti-CD20 mono- clonal antibody used to treat CD20-positive B-cell non- Hodgkin's lymphoma (NHL). Although most of the adverse effects associated with rituximab are usually reversible and temporary infusion-related reactions, including fever, chills, flushing and skin reactions, there are several reports of pulmonary events after long-term administration of rituximab. We present a case of asymp-tomatic nodular organizing pneumonia occurring during rituximab-based chemotherapy in a patient with non- Hodgkin's lymphoma.
B-Lymphocytes ; Chills ; Drug Therapy ; Fever ; Flushing ; Hodgkin Disease ; Humans ; Lymphoma, Non-Hodgkin ; Pneumonia* ; Skin ; Rituximab

A case of generalized pustular psoriasis in a 12 year-old girl is described. She had generalized pustular eruptions on erythematous base, presenting lake of pus, yellowish brown crusts and denudation associated with high fever and chills. With the administration of oral etretinate at a dose of 0.8mg/kg/day for 1 week, rapid and dramatic remission was achieved. About 3 months after her discharge, there developed another wave of new pustules with fever. She was again placed on etretinate therapy. However, there was no expected response as before with developing new pustules continuously. At that time, we tried combination therapy with etretinate and methotrexate. the pustules and erythema began to remit, with eventual clearing of the skin in 6 weeks.
Acitretin* ; Child ; Chills ; Erythema ; Etretinate* ; Female ; Fever ; Humans ; Lakes ; Methotrexate* ; Psoriasis ; Skin ; Suppuration

Tick bites are dermatoses not commonly encountered in Korea. Identification of causative ticks as well as recognition of clinical signs and histopathologic findings are important in making a diagnosis in tick-related dermatoses. Hard ticks which belong to the Family Ixodidae are responsible for most tick-related diseases. Since the first human case of tick bite in Korea was reported in 1982, seventeen cases have been reported up to the present. All the inflicted ticks belonged to the genus Ixodes except a case by Haemaphysalis flava. Among 16 ticks, collected from 16 cases of tick bites caused by the genus Ixodes, nine I. nipponenses, an I. ovatus and I. persulcatus were identified. Recently we experienced 8 cases of tick bites, 6 of them were caused by the genus Ixodes including 4 I. nipponenses. One of them, whose essential complaint was fever and chills, showed the clinical course of tick bite pyrexia which had not been reported in Korea. The clinical and epidemiological findings of tick bites reported in Korea were reviewed, including these 8 cases.
Chills ; Diagnosis ; Fever ; Humans ; Ixodes ; Ixodidae ; Korea ; Skin Diseases ; Tick Bites* ; Ticks*

Dengue fever, which is caused by a mosquito-borne flavivirus, has become a major infectious- disease threat in tropical and subtropical areas. Dengue fever has also become a common cause of febrile infections in persons who have recently traveled. On December 26, 2004 the tsunami hit Southeast Asia. People who survived in those areas were infected with endemic disease such as dengue fever, malaria and cholera. We sent six members of the Korean medical relief team to the tsunami region. Three workers developed fever, chills and headache after leaving the tsunami region, and were diagnosed with Dengue fever. Such an outbreak of Dengue Fever in travelers is rarely reported.
Asia, Southeastern ; Chills ; Cholera ; Dengue* ; Disease Outbreaks ; Endemic Diseases ; Fever ; Flavivirus ; Headache ; Humans ; Malaria ; Tsunamis*

Exflagellation of the malaria parasite microgametocyte usually occurs in the gut cavity of Anopheles mosquitoes following an infective blood meal. Exflagellation is a very rare event in human blood. Due to its rarity, the appearance of this structure in a peripheral blood smear will easily create a diagnostic dilemma. We report a case of malaria with exflagellated microgametes in human blood that was initially mistaken for a double infection of Plasmodium and another blood flagellate. The patient was a 29-year-old Parkistani man presenting with fluctuating fever accompanied by chills and fatigue for 4 days. Initial peripheral blood smear examination showed a number of Plasmodium ring forms, trophozoites, and gametocytes. Additionally, several filamentous structures resembling blood flagellates were seen. With these features, an initial diagnostic impression of combined infection of malaria and blood flagellate was made. Later, we determined that these structures resembling blood flagellates were exflagellated microgametes of malarial parasite. Therefore, the knowledge that exflagellation may appear in human blood with Plasmodium species infection and being more familiar with differentiation of the morphologic features of other species infection can prevent further possible misinterpretation.
Anopheles ; Chills ; Culicidae ; Fatigue ; Fever ; Humans ; Malaria ; Meals ; Parasites ; Plasmodium ; Trophozoites

Generalized pustular psoriasis (GPP) is an acute, systemic form of psoriasis, characterized by fever, chills, rigors, and generalized pustule formation on the skin. The concomitant occurrence of lupus erythematosus and psoriasis has been reported sporadically. But the coexistence of GPP and systemic lupus erythematosus have rarely occurred. We herein report a case of GPP in a 19-year-old female, who has been managed with SLE since the age of 14 years.
Chills ; Female ; Fever ; Humans ; Lupus Erythematosus, Systemic* ; Psoriasis* ; Skin ; Young Adult

Renal vein thrombosis is a rare, renal disease in adults that is related to hypercoagulability. We experienced a case of renal vein thrombosis in a 30-years old woman who presented with fever, chills and left flank pain after delivery. She was treated with catheter-directed thrombolytic therapy and oral anticoagulants.
Adult ; Anticoagulants ; Chills ; Female ; Fever ; Flank Pain ; Humans ; Pregnancy ; Renal Veins* ; Thrombolytic Therapy ; Thrombophilia ; Thrombosis*

Biliary-enteric fistula is a rare disease, and the common causes of biliary-enteric fistula are gallstone, peptic ulcer, malignancy and trauma. It is known that the most common type of biliary-enteric fistula is the cholecysto-duodenal fistula, yet the combination of choledocho-duodeno-colonic fistula is a rare finding. A 78-year-old woman was admitted because she had suffered with right upper quadrant pain, a febrile sense and chills for 2 days. We confirmed the choledocho-duodeno-colonic fistula by performing gastroduodenoscopy, abdominal CT and an upper GI series. So, we report here on an usual case of choledocho-duodeno-colonic fistula, along with a review of the relevant literatures.
Aged ; Biliary Fistula ; Chills ; Female ; Fistula* ; Gallstones ; Humans ; Peptic Ulcer ; Rare Diseases ; Tomography, X-Ray Computed