1.A 10-Year Retrospective Review of Non-Scarring Alopecia in a Tertiary Hospital in Malaysia
Malaysian Journal of Dermatology 2012;29(-):12-15
Background Non-scarring alopecia is a common hair disorder with paucity of
clinical reviews.
Objectives We aim to study the spectrum of non-scarring alopecia, its’ demographic,
clinical and treatment pattern among patients at University Malaya Medical Centre.
Methodology We have retrospectively reviewed the demography, clinical
characteristics and treatment of non-scarring alopecia at University Malaya Medical
Centre (UMMC). A total of 154 records were reviewed.
Results A majority of patients had alopecia areata (28.6%), followed by
androgenetic alopecia (12.3%), telogen effluvium (3.2%), tineacapitis (2.6%) and
unspecified hair loss (53.2). Treatment for alopecia areata included topical steroids
(53.3%), intralesional steroids (26.7%), topical minoxidil (17.8%), oral steroids
(11.1%), oral finasteride (2.2%) and oral azathiopine (2.2%). Prescribed treatment
for androgenetic alopecia comprised of topical minoxidil (68.1%) or oral finasteride
(10.5%).
Conclusion We concluded that alopecia areata was the most common cause of nonscarring
alopecia diagnosed at UMMC and deduced that the high number of patients
diagnosed with unspecified hair loss was attributed to the lack of confidence amongst
out-patient physicians in diagnosing the cause of alopecia.
2.Squamous Cell Carcinoma Arising from Linear Porokeratosis in a Young Chinese Man
Yin YL ; Chew KL ; Koh CK ; Jayalakshmi P
Malaysian Journal of Dermatology 2012;29(-):23-26
Porokeratosis is a specific disorder of epidermal keratinization, characterised
histologically by the presence of cornoid lamella1. Linear is a distinct, mosaic variant
of this autosomal dominant condition. There is a well recognized association between
porokeratosis and malignancy, especially the linear variant which has the highest
malignant potential2, 3.
3.PRE-AURICULAR SINUS: AN UNCOMMON PRESENTATION
WSJ Ng ; YK Chew ; KL Tan ; AW Chong
Malaysian Family Physician 2011;6(1):32-33
An infected pre-auricular sinus presenting as a post-auricular swelling is commonly misdiagnosed as an infected dermoid or
sebaceous cyst. It may even mimic a mastoid abscess leading to further unwarranted investigations and interventions. We
present a case of a 25-year-old Malay man who was initially diagnosed with recurrent infected dermoid cyst. At presentation,
a right post-auricular inflamed swelling was noted with an overlying old incision and drainage scar. An auricular pit was found
at the crus of helix. Using a blunt probe inserted along the sinus tract pus was drained without the need for further surgical
incision. Six weeks after the acute episode, patient underwent excision of the pre-auricular sinus with no evidence of recurrence
at three months follow up. Awareness by the attending physician of this ‘variant type’ of pre-auricular sinus at patient’s first
presentation may negate the need for unnecessary incision and drainage which may subsequently impact the outcome of
surgical excision and reduce the risk of recurrence.
4.Effects of Cast Immobilisation on Skin Barrier Function.
Chin Yee WOO ; Mark Ja KOH ; Winnie Ky FUNG ; Cheri Sh CHAN ; Chong Bing CHUA ; Guan Tzu TAY ; Sanchalika ACHARYYA ; Gloria Fh CHEW ; Nicole Kl LEE ; Kevin Bl LIM
Annals of the Academy of Medicine, Singapore 2020;49(6):354-359
INTRODUCTION:
Cast immobilisation remains the mainstay of treatment for various fractures in paediatric patients, yet patients commonly complain of skin irritation and discomfort. This study aimed to perform a qualitative and quantitative evaluation of the effects of cast immobilisation on the skin of children and adolescents.
MATERIALS AND METHODS:
Patients aged 6-17 years of age with a fracture treated in a fiberglass short-arm or short-leg cast were recruited. Transepidermal water loss (TEWL), stratum corneum (SC) hydration, hair density and presence of any skin signs were assessed before and after cast. Patients were required to complete a weekly questionnaire to rate itch, malodour, warmth, and dampness of the skin under the cast.
RESULTS:
A total of 60 subjects completed the study. Thirty-six patients received a short-arm cast; 24 received a short-leg cast. Upon cast removal, TEWL was significantly increased on the volar surface of the arms and legs ( <0.05), and the dorsal surface of the arm ( <0.05). Likewise, SC hydration was significantly increased at most sites ( <0.05), except the volar surface of the leg ( = 0.513). There was no change in hair density. Throughout the duration of casting, there was an increase in itch and malodour scores.
CONCLUSION
Moderate but significant changes in TEWL, SC hydration and subjective symptoms were observed during the duration of cast immobilisation, demonstrating that cast immobilisation for up to 4 weeks exerts moderate adverse impact on patients' skin. Further studies to explore the use of better materials for cast immobilisation to improve skin barrier function and overall patient satisfaction are warranted.
5.Vulvar basal cell carcinoma: clinical features and treatment outcomes from a tertiary care centre.
Rama P NAMUDURI ; Timothy Yk LIM ; Philip Kl YAM ; Rene GATSINGA ; Soo Kim LIM-TAN ; Sung Hock CHEW ; Mark Ja KOH ; Sorsiah MANSOR
Singapore medical journal 2019;60(9):479-482
We retrospectively reviewed the clinical features, management and outcomes of patients diagnosed with basal cell carcinoma (BCC) of the vulva at the Gynaecological Cancer Centre, KK Women's and Children's Hospital, Singapore, between 1 January 2000 and 28 February 2014. Patients with vulvar BCC were identified from the cancer registry, and their medical records reviewed and analysed. A total of 11 patients with vulvar BCC were identified. Mean age at diagnosis was 63 (range 30-85) years. Ethnically, ten patients were Chinese and one was Malay. Average time from onset of symptoms to diagnosis was 13.8 (range 2-60) months. The most common presenting symptoms were lump and pruritus. All patients were managed surgically. Recurrence was noted in only one patient. Vulvar BCC, although rare, has an excellent prognosis when managed appropriately. Histological diagnosis of all persistent papules, plaques and pigmented lesions is important for early diagnosis.