1.TREATMENT OF HEPATIC HEMANGIOMA BY PERCUTANEOUS TRANS-HEPATIC PUNCTURATION AND INTRALUMINAL INJECTION OF BLEOMYCIN
Chenlong WANG ; Zaiping JING ; Lichen SHAN
Medical Journal of Chinese People's Liberation Army 2001;0(09):-
To evaluate percutaneous trans hepatic puncture and intraluminal bleomycin injection for hepatic hemangioma, 20 patients accepted the therapy. With local anesthesia, a PTC needle was punctured into the lumen of hepatic hemangioma, and the bleomycin was injected. One time a week, and three times made a course of treatment. The total curative ratio was 100%. Fever and distension of the abdomen occurred in 25% of the patients. It is concluded that the method is a mini traumatic and effective therapy for hepatic hemangioma.
2.High stage affective theory of mind in alexithymia:the evidence from eye-movement
Chenlong GU ; Lei ZHANG ; Chunyan ZHU ; Fengqiong YU ; Kai WANG
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(7):601-604
Objective To explore high stage affective theory of mind(ToM) of alexithymics.Methods 24 alexithymics (study group,TAS-20 ≥ 61) and 26 non-alexithymics (control group,TAS-20 ≤ 51) were screened from college students according to the sore of TAS-20.The scores of reading the mind in the eyes test(RMET),fixation numbers and fixation duration in area of interest (AOI) were recorded by HiSpeed Eye Tracker.The data were analyzed by Mann-Whitney U test and Chi-square test.Results There was no differences in scores of RMET between control group and study group (M(Q):23.50(5.00) vs 24.00 (5.00),Z=-1.044,P>0.05).Fixation numbers and fixation duration in study group were higher than those in control group (fixation number:616.00(412.80) vs 579.00(371.30),Z=-2.010,P<0.05;fixation duration:187363.35(106339.28)msvs 139087.55(67335.58)ms,Z=-2.632,P<0.01).Conclusion Alexithymics are impaired in high stage affective ToM.
3.Correlation of Epstein-Barr virus infection with gastric carcinoma
Jian CUI ; Junshu ZHANG ; Biao ZHU ; Chenlong WANG ; Minhua YU ;
Chinese Journal of General Surgery 1997;0(04):-
0.05). EBV DNA positive were found in gastric mucosa of 40.0% in control group, 73.1 %(19/26) in GC tissue(P
4.Effects of dexamethasone on human trabecular meshwork cell volume-sensitive chloride currents induced by hypotonic
Jixue WANG ; Shu LIU ; Chenlong XING ; Yajuan ZHENG
Journal of Jilin University(Medicine Edition) 2014;(6):1144-1148
Objective To analyze the influence of dexamethasone in the hypotonic-induced volume-sensitive chloride currents in human trabecular meshwork cells,and to investigate the possible mechanism of volume-sensitive chloride channels(VACC)in the glucocorticoid-induced glaucoma(GIG)cases.Methods The human trabecular meshwork cells were seeded in 35 mm diameter plastic petri dishes,so that they could grow in monolayer.The cultured cells were divided into normal cell culture medium group and dexamethasone 1 d,3 d,7 d groups.The chlorine current density values of the cells in four groups were recorded respectively by the whole-cell patch-clamp technique. The differences among groups were compared.Results In normal group,after hypotonic stimulation,under+100 and-100 mV voltage clamp,the outward and inward current density values of the trabecular cells were (19.94±0.87) and (-6.53±0.41)pA/pF.In dexamethasone 1 d,3 d,and 7 d groups,under the same condition,the outward and inward current density values of the trabecular cells were (19.39 ± 1.40)and (-6.42 ± 0.28)pA/pF, (17.97±2.35)and (-5.82±0.94)pA/pF,(17.16±1.16)and (-5.65±0.43)pA/pF.The trabecular cells cultured with dexamethasone for 1 d had lower outward and inward current density values under hypotonic stimulation compared with normal group,but there was no significant difference (P>0.05).The trabecular cells cultured with dexamethasone for 3 d and 7 d,when compared with normal group,had significantly lower outward and inward current density values under hypotonic stimulation (P<0.05 ). Conclusion Dexamethasone could reduce the volume-sensitive chloride current in trabecular meshwork cells,which would affect trabecular meshwork cell volume adjustment.This would possibly cause the increase of the aqueous humor outflow resistance among GIG cases.
5.Theory of mind impairment in youngsters affected by alexithymia
Chenlong GU ; Chunyan ZHU ; Mingming ZHANG ; Liqin YANG ; Kai WANG ; Fengqiong YU
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(7):605-607
ObjectiveTo study theory of mind(TOM) of youngsters in alexithymia,and to assess the impairment in TOM by analysing affective and cognitive TOM and the first and second order judgment.MethodsTOM of 31 alexithymics and 30 healthy control subjects get be examined by the Chinese version of “Yoni task” and series of tests.ResultsThere were significant differences in affective TOM accuracy scores between alexithymics and healthy controls ( ( 35.81 ± 6.30) vs ( 39.83 ± 6.02),t =-2.55,P < 0.05 ).Particularly,alexithymics got significantly lower accuracy scores in the second order judgement of affective TOM ( (24.55 ±6.01 ) vs (28.80 ± 6.04),t =-2.76,P < 0.01 ).However,there were no in cognitive TOM accuracy scores between alexithymics and health controls ( ( 19.00 ± 2.11 ) vs ( 19.43 ± 2.13 ),t =-0.80,P > 0.05 ).ConclusionAlexithymics are impaired in affective TOM,specially the second order judgement.
6.Calibration and comparison analysis of same brand of different types of hematology analyzer
Kaituo PAN ; Chaoxin JIAGN ; Lingheng ZENG ; Chenlong WANG ; Wenke CHEN ; Qingyang ZENG
International Journal of Laboratory Medicine 2017;38(5):587-590
Objective To conduct the calibration and comparative analysis on the Mindray BC 5800 automated hematology analy-zer in our department for ensuring the traceability and consistency of experimental results .Methods The mating calibrator of the Mindray company was used to conduct the calibration in the Mindray BC5800 automated hematology analyzer ,after calibration ,the calibration verification was performed .After passing the calibration verification ,the fresh blood was conduct the fixed value ,then the Mindray BC5800 and BC5180 automated hematology analyzers were calibrated ,after calibration ,the calibration verification was conducted ,after passing the calibration verification ,with the BC5800 as the standard instrument and BC5180 as the comparison in-strument ,the comparison experiment of fresh blood was performed .Results The Mindray BC5800 ,BC5300 and BC5180 automated hematology analyzers were passed the calibration verification after calibration ,in the comparison experiment of fresh blood ,the rela-tive deviation coincidence rates of WBC ,RBC ,Hb ,MCV ,PLT ,HCT ,MCH and MCHC between BC5800 and BC5300 and between BC5800 and BC5180 all exceeded 80% ,the comparison tests were passed .Conclusion The hematology analyzer should be per-formed the calibration verification and comparison test after calibration ,and the comparison test must be passed for ensuring the traceability of results and comparability among the test results in order to meet clinical needs .
7.Botanical characters of test-tube plantlets and seed plantlets in Bupleurum chinense
Bo LI ; Guiru HAO ; Qi CHANG ; Chenlong LI ; Lirong WANG ; Jianping HAO
Chinese Traditional and Herbal Drugs 1994;0(10):-
Objective To provide a scientific basis for the creation and promotion of the rapid propagation of excellent Bupleurum chinense and study on botanical characters of test-tube plantlets and seed plantlets in B.chinense.Methods B.chinense with high effective medicinal ingredients and great stability of genetic characters was selected for rapid propagation,and some of botaninal characters between test-tube plantlets and seed plantlets were compared.Results The tiller number,the branch stem number,and the inflorescence number of the test-tube plantlets were significantly greater than those in seed plantlets.Conclusion Through the rapid propagation and the large-scale cultivation of test-tube plantlets of B.chinense,much more roots and seeds are obtained comparing with those of seed plantlets,while maintaining the excellent traits of B.chinense.
8.Analysis of the characteristics of eye movement changes in patients with acute cerebral infarction characterized by dizziness or vertigo
Wei WANG ; Chenlong WANG ; Hong ZHOU
Chinese Journal of Postgraduates of Medicine 2023;46(9):850-855
Objective:To analyze the characteristics of eye movement changes in patients with acute cerebral infarction characterized by dizziness or vertigo.Methods:The clinical data of 114 patients characterized by dizziness or vertigo in the Civil Aviation General Hospital from January 2021 to June 2022 were retrospectively analyzed. Among them, acute cerebral infarction was in 74 cases (acute cerebral infarction group), including anterior circulation infarction 32 cases, posterior circulation infarction 42 cases; benign paroxysmal positional vertigo (BPPV) was in 40 cases (BPPV group). The clinical manifestation and the results of videonystagmography (VNG) examination were recorded.Results:There were no statistical differences in the incidences of visual shaking, dysarthria and paresthesia between two groups ( P>0.05); the incidence of visual rotation in acute cerebral infarction group was significantly lower than that in BPPV group: 25.68% (19/74) vs. 100.00% (40/40), the incidence of limb weakness and walking instability were significantly higher than those in BPPV group: 29.73% (22/74) vs. 0 and 39.19% (29/74) vs. 0, and there were statistical differences ( P<0.01). The result of VNG examination showed that the abnormal incidences of eye movement and positional test in acute cerebral infarction group were significantly lower than those in BPPV group: 74.32% (55/74) vs. 100.00% (40/40) and 2.70% (2/74) vs. 100.00% (40/40), the abnormal incidences of gaze-holding test, without fixation test, randomly saccade test, smooth pursuit test and optokinetic nystagmus test were significantly higher than those in BPPV group: 10.81% (8/74) vs. 0, 21.62% (16/74) vs. 0, 45.95% (34/74) vs. 2.50% (1/40), 60.81% (45/74) vs. 5.00% (2/40) and 21.62% (16/74) vs. 0, and there were statistical differences ( P<0.01 or <0.05). There were no statistical differences in the incidences of visual rotation, visual shaking, dysarthria, walking instability and paresthesia between anterior circulation infarction patients and posterior circulation infarction patients ( P>0.05); the incidence of limb weakness in patients with anterior circulation infarction was significantly higher than that in patients with posterior circulation infarction: 50.00% (16/32) vs. 14.29% (6/42), and there was statistical difference ( P<0.01). The result of VNG examination showed there were no statistical differences in the abnormal incidences of eye movement, gaze-holding test, without fixation test, randomly saccade test, smooth pursuit test, optokinetic nystagmus test and position test between anterior circulation infarction patients and posterior circulation infarction patients ( P>0.05). Conclusions:The abnormal incidence of eye movements in patients with acute cerebral infarction is relatively high, and VNG examination can help reflect changes of the eye movement pathway in the brain.
10.Malignant brain edema after endovascular treatment of acute ischemic stroke: predictive factors, prevention and treatment
Huigui ZHAO ; Yasuo DING ; Chenlong WANG
International Journal of Cerebrovascular Diseases 2023;31(1):42-47
Malignant brain edema is one of the serious complications of acute ischemic stroke, which is not uncommon after endovascular treatment, and can significantly reduce the benefits of endovascular treatment, leading to poor outcomes and even death of patients. Therefore, early identification and timely treatment are particularly important. This article reviewed the predictive factors, prevention and treatment of malignant brain edema in patients with acute ischemic stroke who received endovascular treatment.