Objective To observe the effect of artificial tears in the treatment of xerophthalmia after cataract surgery with phacoemulsification combined with intraocular lens implantation.Methods 384 patients with 384 xerophthalmia eyes after cataract surgery with phacoemulsification combined with intraocular lens implantationwere selected.They were randomly divided into observation group and control group,192 eyes in each group.Conventional therapy was given in the control group,and artificial tears was added in the observation group.The SIT,FL,BUT and adverse reactions were observed and compared.Results There were improvement of SIT,FL and BUT in both two groups after treatment.The SIT (mm/5min)in the observation group was (13.97 ±1.72),that was (9.12 ±1.02) in the control group,the improvement of SIT in the observation group was better than the control group (t =2.942, P <0.05).The FL (s)in the observation group was (2.06 ±0.37),that was (3.71 ±0.72)in the control group, the improvement of SIT in the observation group was better than the control group (t =1.776,P <0.05).The BUT (s)in the observation group was (13.26 ±2.04),that was (7.99 ±2.16)in the control group,the improvement of BUT in the observation group was better than the control group (t =4.098,P <0.05).There were 39 cases of healing eyes in the observation group,and healing rate was 27.46%.There were 21 cases of healing eyes in the control group, the healing rate was 14.79%.The healing rate in the observation group was higher than the control group (χ2 =7.748,P <0.05 ).There were 183 cases of effective treated eyes in the observation group,the effective rate was 93.66%,and there were 120 cases of effective treated eyes in the control group,the effective rate was 84.51%.The effective rate in the observation group was higher than the control group (χ2 =7.094,P <0.05).Conclusion It is effective to apply artificial tears in the treatment of xerophthalmia after cataract surgery with phacoemulsification com-bined with intraocular lens implantation and safe.It is worthy of clinical application.

Bladder cancer is the most common malignant tumor in the urinary system.Currently,the clinical treatment options for bladder cancer mainly include surgery,chemotherapy,radiotherapy,immunotherapy,targeted therapy,photodynamic therapy,combination therapy,etc.The conventional treatment and administration strategies for bladder cancer primarily depend on the tumor stage and the extent of metastasis.However,in the process of non-surgical treatment,drugs lack specificity and targeting.Once the dosage is improperly controlled,drugs will damage normal cells when attacking cancer cells,which will lead to poor efficacy and multiple side effects.Nanomedicine is an emerging interdisciplinary field that utilizes nanomaterials and technologies in nanomedicine to provide disruptive technologies for traditional treatments,with advantages such as targeted delivery and high efficiency with low toxicity.Many nanotechnologies have become hot topics in clinical research in the field of medicine.Functionalized nanoparticles can actively or passively target specific cells within target organs,such as bladder cancer cells,by altering their surface properties,thereby enhancing drug delivery precision,reducing damage to normal cells,and improving treatment efficacy.This article provides an overview of the progress in classical and novel treatment approaches to bladder cancer,with a particular focus on the potential applications and future development directions of nanotechnology in the treatment of bladder cancer,providing important reference for personalized therapy and clinical translation in bladder cancer.