Objective To investigate the experience of microinvasive surgical occlusion of ventricular septal defect (VSD).Methods A total of 142 children with VSD was given microinvasive surgical occlusion from March 2009 to December 2013 at our hospital.There were 90 males and 52 females,the age ranged from 8 months to 11 years,and body weight from 7 kg to 35 kg,and ventricular septal defects were divided into membranous type,film cycle headquarter type,pulmonary valve type,and muscle type.The diameter of VSD was 2 ～ 10 mm.Under general anesthesia,an incision was made in the lower part of sternum or intercostals space,and a special occluder was inserted to close the ostium via right ventricle puncture under the guidance of transesophageal echocardiography.Results A total of 139 cases had successful occluded with a 97.8％ of successful rate,using blocking umbrella 4 ～ 12#,including 25 eccentric umbrella.Two cases were operated under extracorporeal circulation because of aggravated aortic valve insufficiency.One case without handled muscular ventricular septal defect combined atrial septal defect for guide wire pass muscular defect failed.Full set did not have death and third degree A-V block.Conclusions Microinvasive surgical occlusion is easy to handle,operation-time short,and relative broad for the closure of ventricular septal defect.It has a fast recovery and good effectiveness with a beautiful outlook and safety.

Objective To observe the anagesia effectof PCIA (patient-controlled intravenous analgesia)with flurbiprofen anddezocine on obstructivesleep apnea sydrome (OSAS)patients under-going uvula palatopharyngoplasty.Methods Sixty OSAS patients,aged 26-59 years,using PCIA af-ter UPPP were randomly divided to three groups (n=20 each):patients in group FD started the PCIA with flurbiprofen 1 mg/kg+dezocine 0.4 μg/kg+Azasetron in 100 ml saline after surgery, while these in group D with dezocine 0.4μg/kg+Azasetron,group S with sulfentanyl 2μg/kg+Aza-setron (background infusion 2 ml/h,single lose 0.2 ml/h,load doses 5 ml/h,lock time 15 min)VAS scores of 1,2,6,12,24,48 h after surgery and the incidence of nausea,vomiting,drowsiness,pruri-tus,were recorded.Results All group patients showed good pain relieve.There were no significant differences in VAS scores observed in three groups.The side effect incidence for group FD,D and S was 5%,10% and 30%.Conclusion PCIA with flurbiprofen and dezocine can provide good anagesia effect and mild side effects on UPPP patients.