1.Stage-I functional reconstruction of traumatic deviated nose deformity with chronic rhino-sinusitis
Chengyuan WANG ; Jianwu SONG ; Dazhang YANG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(05):-
OBJECTIVE To explore the feasibility, surgical method, surgical effect and postoperative complications of stage-I functional reconstruction of traumatic deviated nose deformityaccompanied with chronic rhino-sinusitis.METHODS 37 patients with traumatic deviated nose deformity accompanied with chronic rhino-sinusitis were selected in this study.Methods of stage-I reconstruction included endoscopic nasal septoplasty, functional endoscopic sinsus surgery(FESS), turbinectomy, rhinoplasty and so on.The patients were followed up for one month after operation.The shape of the nose was observed and the nasal bias was measured also.At 3 months after operation, the therapeutic effect about the chronic nasosinusitis was estimated by endoscopic check and patients' subjective symptom.The data obtained preoperatively and postoperatively were treated with statistical methods.RESULTS 37 patients with traumatic deviated nose deformity were selected in this study.The postoperative bias was 2.04 ?0.97 mm and preoperative bias was(6.64?2.21) mm.A t-test revealed the significant difference between pre-and postoperative bias(t=6.374, P
2.Social network analysis of health information users based on Sina microblogs
Xue LAN ; Jindan CAO ; Chengyuan YANG
Chinese Journal of Medical Library and Information Science 2015;24(10):54-59
The structure of social network and its information spreading characteristics in 41 users of Sina microb-logs were studied , which showed that the exchange level was quite low in the 41 users of health information in Sina microblogs, usually in small groups.Although the 41 users were found in the core area, their exchange was sporadic even with no exchange in the core nodes or in other nodes, thus effective information sharing could not be achieved and information could not be widely spread .
3.MRI manifestations and differentiated diagnosis of postoperative spinal complications.
Haitao, YANG ; Renfa, WANG ; Tianyou, LUO ; Yu, OUYANG ; Fajin, LV ; Liming, XIA ; Chengyuan, WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2009;29(4):522-6
To analyze MR manifestations of postoperative spinal complications and investigate the value of MRI in the diagnosis and differentiated diagnosis, 114 cases of spinal postoperative complications were analyzed retrospectively and compared with the clinical data. The results showed that the main postoperative spinal complications included spinal stenosis (n=33, consisting of 21 cases of epidural fibrosis and 12 cases of epidural hematoma or epidural abscess), lack of spinal stability (n=43), infection (n=23, consisting of 7 cases of para-spinal soft-tissue infection, 5 cases of vertebral discitis, 4 cases of vertebral and appendix infection, 3 cases of epidural abscess, 2 cases of myelitis, 2 cases of spinal arachnoiditis), others (n=28, consisting of 12 cases of inner fixation failure, 9 cases of epidural hematoma, 7 cases of cerebrospinal fluid gusher). It is concluded that MRI can specifically display all kinds of postoperative spinal complications, and is of significant value in the diagnosis and differentiated diagnosis of postoperative spinal complications.
4.Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression.
Jun, XIA ; Jun, CHEN ; Yicheng, ZHOU ; Jingfeng, ZHANG ; Bo, YANG ; Liming, XIA ; Chengyuan, WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(5):500-2, 506
In order to explore the MRI volume of the amygdala and hippocampus in patients with major depression, quantitative MRI of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. The results showed that both groups exhibited similar significant hippocampal asymmetry (left smaller than right). The volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. The patients had significant asymmetry of the amygdalar volumes (right smaller than left). No correlation was found between hippocampal volume abnormalities and ill duration. It was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression.
Amygdala/*pathology
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Anthropometry
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Depressive Disorder, Major/*pathology
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Hippocampus/*pathology
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Magnetic Resonance Imaging
5.Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression.
Jun XIA ; Jun CHEN ; Yicheng ZHOU ; Jingfeng ZHANG ; Bo YANG ; Liming XIA ; Chengyuan WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(5):500-506
In order to explore the MRI volume of the amygdala and hippocampus in patients with major depression, quantitative MRI of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. The results showed that both groups exhibited similar significant hippocampal asymmetry (left smaller than right). The volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. The patients had significant asymmetry of the amygdalar volumes (right smaller than left). No correlation was found between hippocampal volume abnormalities and ill duration. It was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression.
Adult
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Amygdala
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pathology
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Anthropometry
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Depressive Disorder, Major
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pathology
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Female
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Hippocampus
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pathology
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Humans
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Magnetic Resonance Imaging
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Male
6.Breeding of high-oil Jatropha curcas L for biodiesel production.
Chengyuan YANG ; Zhen FANG ; Bo LI ; Gang LIU ; Jianzhong LI
Chinese Journal of Biotechnology 2010;26(11):1514-1525
Different geographic seed sources (80) of Jatropha curcas L. were collected in South China and planted in a germplasm resource garden to study their biological and agricultural properties. The average ground diameter, tree height and crown size of two-year old plants of the 80 sources was 7.6 cm, 167 cm and 114 cm, respectively, the average 1000-seed weight was 0.676 (0.477-0.876) kg. The trees grew further to the average size of 12.6 cm diameter, 2.69 m height and 2.1 m crown at the 4th year. Among the 80 sources, six sources had higher oil yield (seed oil content of 40%-42%) and better behaving in expression of phenotype were selected for a small-scale trial of forestation to determine oil yield. Among them a provenance with outstand in expression of phenotype yielded 964.3, 2000.6 and 2858.7 kg/ha was achieved for two- three- and four-year old trees, respectively. Additionally, a new Jatropha mutant was found in the wild and hybridization experiments showed that its oil content increased by 6%.
Biofuels
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Breeding
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Culture Techniques
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methods
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Jatropha
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genetics
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growth & development
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metabolism
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Mutation
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Plant Oils
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analysis
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Seeds
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growth & development
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metabolism
7.Etiology and treatment of delayed epistaxis after endoscopic surgery.
Honglei HAN ; Chengyuan WANG ; Jianfeng LIU ; Yuan LI ; Naya WANG ; Dazhang YANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2011;25(20):925-928
OBJECTIVE:
To evaluate the etiology and management of delayed epistaxis after endoscopic surgery.
METHOD:
To retrospectively analyze the clinical data of 11 cases for epistaxis after nasal endoscopic surgery. To compare their precipitating factors, their surgical approach, time and site of bleeding and management in order to find the intrinsic rules.
RESULT:
The precipitating factors, bleeding sites and treatments varied among patients.
CONCLUSION
Delayed epistaxis after endoscopic surgery can not be neglected. There may be some precipitating factors. The surgical approach may be related to the bleeding site. It is better to treat the epistaxis using the endoscope to explore the bleeding site and to give corresponding intervention.
Adult
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Endoscopy
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adverse effects
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Epistaxis
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etiology
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therapy
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Female
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Humans
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Male
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Middle Aged
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Postoperative Complications
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etiology
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therapy
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Retrospective Studies
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Young Adult
8.Effects of different therapeutic methods and typical recipes on activation of ERK1/2 in Kupffer cells of rats with fatty liver
Minjie MENG ; Qinhe YANG ; Qiang WANG ; Xuemei CHEN ; Fengzhen WANG ; Yanping WANG ; Hailan TANG ; Shaobing CHENG ; Jiasheng LING ; Chengyuan WEN ; Fang XIE
Chinese Journal of Pathophysiology 2000;0(08):-
AIM: To investigate effects of different therapeutic methods and typical recipes on activation of ERK1/2 in Kupffer cells of rats with fatty liver.METHODS: The rat model of fatty liver was established by feeding high fat diet combinated with distillate spirit.Meanwhile Chinese medicines Shugan fang,Jianpi fang,Huoxue fang,Qushi fang,and Zonghe fang were given to treat different groups respectively.12 weeks later,the Kupffer cells were isolated from livers of control group,model group and different treatment groups by sequential in situ perfusion with collagenaseⅣ and pronase E,density gradient centrifugation,selective adherence.The expression of total ERK1/2 and phospho-ERK1/2 in Kupffer cells of control group,model group and different treatment groups were detected by Western blotting.RESULTS: The expressions of total ERK1/2 and phospho-ERK1/2 were higher in Kupffer cells from model group than those in control group(P
9.Early local flap reconstruction in nasal defect due to severe infection after rhinoplasty.
Chengyuan WANG ; Dazhang YANG ; Shiwei LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009;23(12):549-552
OBJECTIVE:
To explore the feasibility, option of surgical method and surgery opportunity of local flap reconstruction in nasal defects due to severe infection after rhinoplasty.
METHOD:
The clinical datum of eleven patients, who had 15 cases of local flap reconstruction due to severe infection after rhinoplasty, were analyzed retrospectively. The lesions included defects of nasal dorsum, nasal tip and anterior-nare-vestibular fistula. Areas of defects ranged from 1.5 cm x 1.2 cm to 2.0 cm x 2.5 cm and fistula diameters fell between 0.6 cm and 0.9 cm. Based on the principal of nasal aesthetic sub-unit, nasal defects were restored with local flaps, such as nasal dorsum flaps, rhomboid flaps and nasal columella-tip flaps. The early changes and the maintenances of nasal contour after reconstruction were observed.
RESULT:
All 15 reconstructions were carried out 2 weeks after control of infection, and stage-I recovery was achieved in all the cases. In the follow-up periods from 4 to 27 months, all the flaps survived. only 2 cases had distortion of nasal tips, however, they were recovered with subcutaneous injection restoration; the other cases received satisfactory nasal contour where the flaps matched well with the neighbor skin in color, texture and extent of actinic dermatitis.
CONCLUSION
Based on the principal of nasal aesthetic sub-unit, the individualized early local flap reconstruction would have good effect on nasal function and aesthetics, which will restore self-confidence of the patients as soon as possible.
Adult
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Female
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Humans
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Infection
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complications
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Male
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Postoperative Complications
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surgery
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Reconstructive Surgical Procedures
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methods
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Rhinoplasty
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adverse effects
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Skin Transplantation
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Surgical Flaps
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Young Adult
10.Correlation study between lipid levels and the risk of multiple system atrophy
Shuyu ZHANG ; Jie TIAN ; Changhe SHI ; Chengyuan MAO ; Yapeng LI ; Haiyang LUO ; Haiman HOU ; Yongli TAO ; Jing YANG ; Jun WU ; Bo SONG ; Yuming XU
Chinese Journal of Neurology 2016;49(3):232-236
Objective To look for more serum biomarkers supporting the diagnosis of multiple system atrophy ( MSA) and providing more evidence for early treatment.Methods All patients and healthy controls were enrolled from January 2011 to March 2015 in the First Affiliated Hospital of Zhengzhou University.Demographic features and biochemical examination results were collected.The t test was used to compare the lipid levels between MSA patients and controls.LSD-t test was used to compare the lipid levels among subtypes of MSA patients.Multivariate Logistic regression analysis was conducted to analyze the influencing factors.The relevance between lipid levels and onset age, disease duration and Hoehn & Yahr stage was calculated by Spearman correlation coefficients.Results Participants included 195 MSA patients and 195 age-and gender-matched controls with no neurological diseases.The levels of total cholesterol ((4.33 ±0.90) mmol/L), triglyceride ((1.27 ±0.71) mmol/L), low-density lipoprotein (LDL;(2.70 ±0.76) mmol/L) were significantly lower in patients than in controls ((4.52 ±0.85), (1.47 ± 0.86), (2.85 ±0.71) mmol/L ,t=2.056,2.528 and 2.149 respectively, all P<0.05).The levels of total cholesterol ((4.28 ±0.96) mmol/L) and triglyceride ((1.20 ±0.64) mmol/L) were significantly lower in MSA-P patients than in control group ((4.52 ±0.85), (1.47 ±0.86) mmol/L;LSD-t=1.983, 2.566, both P<0.05).After adjusting for age, gender and histories, the odds ratio ( OR) was 0.31 (95%CI 0.15-0.65, P =0.002 ) for MSA patients in the highest quartile of triglyceride and 0.38 (95%CI 0.17 -0.83,P=0.016) for those in the highest quartile of high-density lipoprotein (HDL), compared with the lowest quartiles.And HDL level was in a significantly positive correlation with onset age (r=0.15, P=0.039).Conclusion Our data suggest that triglyceride and HDL may be associated with the prevalence of MSA, and the lower levels of HDL, the earlier onset of MSA.