Objective To analyze the clinical diagnosis value of Color Doppler Flowing Imaging in the diag-nosis of female breast mass ,discuss sonographic features of breast hyperplasia and maeexy dyeplesle .Methods The data of 20 patients with breast disease which diagnosed by Color Doppler Flowing Imaging were retrospectively ana -lyzed,some cases were conducted postoperative pathological examination .Results In all cases,13 cases were breast fibroadenoma(65.0%),6 cases were maeexy dyeplesle (30.0%),1 case was metaplastic squamous cell carcinoma (5.0%).The typical fibroadenoma had regular shape ,clear boundary and homogeneous internal echo ,and were mar-ginated smoothly with a fine echoic capsule and a lateral wall shadowing .Conclusion Color Doppler ultrasonography is an approach for noninvasive and simple examination of breast lesion ,and worthwhile for spreading in clinical prac-tice .Analysis of the ultrasonographic performance of breast fibroadenoma is helpful to the diagnosis and differential di -agnosis of breast disease ,which can also improve the level of diagnosis .

Objective To explore the early(Ⅰ,Ⅱ)in modified radical mastectomy of breast cancer clinical value of preserving intercostobrachial nerve.Methods A retrospective analysis of 62 cases of early breast cancer patients with the clinical data,on intraoperative complete preservation of the intercostobrachial nerve in 46 cases as the observation group,intraoperative resected intercostobrachial nerve in 16 cases as control group,comparative analysis of the two groups after the upper medial arm and axilla skin paresthesia and breast cancer recurrence.Results All 62cases underwent modified radical mastectomy of breast cancer,all patients were cured.The observation group upper medial arm and axillary skin sensory abnormalities in 5 cases(10.9％),significantly lower than the control group of 16 cases(100％)(x2 =19.27,P ＜0.05).A mean follow-up of 1 year,the observation group in upper arm skin party abnormalities in patients with 5 cases,after 1 ～ 3 mongths recovery ;control group of sensory abnormalities were not returned to normal; the two groups were not found in local tumor recurrence or distant metastasis.Conclusion In modified radical mastectomy of breast cancer reserving intercostobrachial nerve was feasible,and could significantly reduce the postoperative lateral medial arm and axilla skin feeling abnormal rate,and improve the quality of life in patients.

Radiotherapy uses high-energy X-rays or other particles to destroy cancer cells and medical practitioners have used this approach extensively for cancer treatment (Hachadorian et al., 2020). However, it is accompanied by risks because it seriously harms normal cells while killing cancer cells. The side effects can lower cancer patients' quality of life and are very unpredictable due to individual differences (Bentzen, 2006). Therefore, it is essential to assess a patient's body damage after radiotherapy to formulate an individualized recovery treatment plan. Exhaled volatile organic compounds (VOCs) can be changed by radiotherapy and thus used for medical diagnosis (Vaks et al., 2012). During treatment, high-energy X-rays can induce apoptosis; meanwhile, cell membranes are damaged due to lipid peroxidation, converting unsaturated fatty acids into volatile metabolites (Losada-Barreiro and Bravo-Díaz, 2017). At the same time, radiotherapy oxidizes water, resulting in reactive oxygen species (ROS) that can increase the epithelial permeability of pulmonary alveoli, enabling the respiratory system to exhale volatile metabolites (Davidovich et al., 2013; Popa et al., 2020). These exhaled VOCs can be used to monitor body damage caused by radiotherapy.
Breath Tests/methods* ; Exhalation ; Humans ; Quality of Life ; Respiratory System/chemistry* ; Volatile Organic Compounds/analysis*