1.Ethical Problems and Countermeasure in Clinical Teaching of Sexually Transmitted Disease
Chengxin ZUO ; Jinhua HUANG ; Jing CHEN ; Jangyun LU ; Yaping XIANG
Chinese Medical Ethics 1994;0(06):-
Owing to medical students'joining in, the correlation between doctors and patients have expanded into the relationship between doctors and medical students and patients in clinical teaching of sexually transmitted disease ( STD). It is easy to disobey ethical principle and lead to medical dispute happened if not be cautious to deal with the relationship. So we present that ① strictly to following medical ethical principle; ② establishing a harmonious doctor - patient relationship; ③improveing teaching ways to a rational extent in medical treatment of medical students were concerned with patients, and disposing the relationship between " Teaching" and " Learning" ; ④enhancing the professional morality culture of doctors( clinical teachers) and medical students, and providing the high quality service for patients. Thus ethical problems can be avoided effectively in clinical teaching of STD, and clinical teaching can be ensured go on wheels effectively too.
2.Expression of CTGF mRNA in sclerotic skin of mice with bleomycin-induced scleroderma
Zhaohui LIAO ; Jianyun LU ; Jing CHEN ; Yaping XIANG ; Chengxin ZUO ; Suiyu HU
Chinese Journal of Dermatology 1995;0(01):-
Objective To investigate the expression of connective tissue growth factor(CTGF) mRNA in the sclerotic skin of mice with bleomycin (BLM)-induced scleroderma. Methods Twenty-four SPF female BALB/c mice were randomly divided into the model group and the control group. The model mice were subcutaneously injected on the back with 0.1 mL of BLM (300 ?g/mL, diluted in saline) daily for 4 weeks, while the controls were injected with saline in the same manner. After the final injection the skin section in the injected area was collected for histological examination, measurement of dermis thickness, determination of hydroxyproline contents by a colorimetric method, detection of CTGF mRNA expression by in situ hybridization and measurement of CTGF and pro-collagen ?1(pro-COL1A1) mRNA expression by semiquantitative RT-PCR. Results Compared with the control mice, the model mice showed typical scleroderma histologically. The dermis was significantly thicker and the skin hydroxyproline content was significantly higher in the model group than that in the controls (both P
3.Correlation between facial nerve functional evaluation and efficacy evaluation of acupuncture treatment for Bell's palsy.
Zhangling ZHOU ; Chengxin LI ; Yuebo JIANG ; Cong ZUO ; Yun CAI ; Rui WANG
Journal of Integrative Medicine 2012;10(9):997-1002
To assess and grade facial nerve dysfunction according to the extent of facial paralysis in the clinical course of acupuncture treatment for Bell's palsy, and to observe the interrelationship between the grade, the efficacy and the period of treatment, as well as the effect on prognosis.
4.Association of long working hours and shift work with occupational stress in level A tertiary hospitals
CI Xiaoyu ; ZUO Shurui ; LI Tao ; HAN Yicheng ; HE Ping ; YANG Chengxin
Journal of Preventive Medicine 2023;35(7):553-557
Objective:
To examine the association of long working hours and shift work with occupational stress among medical staff in level A tertiary hospitals, so as to provide insights into promotion of physical and mental health among medical personnel.
Methods:
One level A tertiary hospital was sampled using a stratified cluster sampling method from southern and northern Xinjiang Uygur Autonomous Region, and all medical personnel were recruited from these two hospitals. Participants' demographics, working duration, and working in shifts were collected using questionnaires, and occupational stress was measured using the Core Scale for Measurement of Occupational Stress proposed by National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention. The associations of long working hours (weekly working duration of >40 hours) and shift work with occupational stress were examined using a multiple linear regression model.
Results:
A total of 2 529 questionnaires were allocated, and 2 262 were valid, with an effective rate of 89.44%. The respondents had a mean age of (35.12±8.71) years, and included 1 696 women (74.98%). Of all respondents, there were 722 doctors (31.92%), 1 033 nurses (45.67%), 361 medical or pharmaceutical technicians (15.96%), 1 808 with long working hours (79.93%) and 1 264 with shift work (55.88%). The score of occupational stress was (44.79±8.49) points, and the prevalence of occupational stress was 28.69% among respondents. Multiple linear regression analysis showed that after adjustment for age, marital status, length of service, position, smoking and physical exercise, long working hours (>40 h, β'=0.124; >48 h, β'=0.175; ≥55 h, β'=0.323) and shift work (β'=0.203) were influencing factors for occupational stress among medical personnel(P<0.05); however, there was no interaction between long working hours and shift work (P>0.05).
Conclusion
Long working hours and shift work may increase the risk of occupational stress among medical personnel in level A tertiary hospitals.
5.Evaluation of the rehabilitation therapy outcome for pneumoconiosis patients in the rehabilitation station
Yicheng HAN ; Qian YANG ; Shurui ZUO ; Xuedan LI ; Chengxin YANG ; Ping HE
China Occupational Medicine 2024;51(2):214-218
ObjectiveTo explore the rehabilitation outcome of personalized pulmonary rehabilitation therapy in pneumoconiosis patients in the rehabilitation station. Methods A total of 42 pneumoconiosis patients were selected as the study subjects from seven pneumoconiosis rehabilitation stations in Xinjiang Uygur Autonomous Region using the judgment sampling method. Patients were treated with personalized rehabilitation therapy for three months, and the outcome was analyzed. Results The six-minute walking test distance, maximum inspiratory pressure, maximum expiratory pressure, forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and FEV1/FVC ratio of the pneumoconiosis patients were higher after rehabilitation therapy than those before therapy (all P<0.05). The score of Chronic Obstructive Pulmonary Disease Assessment Test of patients after therapy was lower than that in pre-treatment (P<0.05). There was no significant difference in respiratory difficulty, Borg scale, balance ability, depression symptoms, anxiety symptoms, nutritional status scores, body mass index, blood oxygen saturation, and heart rate before and after rehabilitation therapy (all P>0.05). Conclusion The individualized pulmonary rehabilitation therapy of pneumoconiosis patients at pneumoconiosis rehabilitation station can improve the respiratory muscle strength and lung function of patients, and improve their quality of life.
6.Propranolol in the treatment of problematic infantile hemangiomas.
Jianyun LU ; Guizhi QIN ; Jinhua HUANG ; Suo LI ; Jing ZHAO ; Yaping XIANG ; Jing CHEN ; Chengxin ZUO ; Shengbo YANG ; Lina TNA
Journal of Central South University(Medical Sciences) 2011;36(11):1102-1105
OBJECTIVE:
To evaluate the short-term efficacy and safety of propranolol for problematic infantile hemangiomas.
METHODS:
Oral propranolol was administered to 68 infants with heamngiomas diagnosed by clinical evaluation and adjuvant examination at 1.0~2.0 mg per kilogram of body weight per day, divided to 2 or 3 times. The patients revisited once a month. The changes of the tumor size, texture, and color were monitored and recorded at a regular interval.The adverse effects after medication were observed and managed accordingly.The short-term results were evaluated using a 4-grade system.
RESULTS:
All the 68 infants were followed up for 3-13 months, except that 1 infants combined with other diseases and 4 withdrew.The overall response was Scale 1 in 8 infants, Scale II in 13, Scale III in 29, and Scale IV in 13. No serious adverse effects were seen, but none cured entirely as well.
CONCLUSION
Oral propranolol is safe and effective for infantile heamngioma with good short-term result. It could be used as the primary drug for problematic infantile hemangiomas at the rapid growth stage of hemangiomas.
Female
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Hemangioma
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drug therapy
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Humans
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Infant
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Male
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Propranolol
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therapeutic use
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Prospective Studies
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Skin Neoplasms
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drug therapy
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Subcutaneous Tissue