1.An investigation of functional characteristics of traumatic brain injuries occurred in earthquake
Qiang GAO ; Chengsen JIA ; Min GUAN ; Chengqi HE
Chinese Journal of Physical Medicine and Rehabilitation 2008;30(12):805-807
Objective To investigate the functional characters of traumatic brain injuries occurred in wenehuan earthquake.Methods Thirty-eight cases with brain injury,occurred in Wenchuan earthquake,hospitalized in intensive care unit and brain surgery wards of Wenchuan China Hospital were enrolled in the study.Glasglow coma scale(GCS)was used to assess the severity of brain injury,mini-mental state examination(M MSE)was used to assess the cognitive function,the modified Ashworth scale was applied to aSSeSS the muscle tone,the Bobath balance scale was applied to assess the sitting and standing balance.the modified Barthel index Was applied to evaluate the activities of daily living(ADL).Resuits Mean age of the patients was 46 years,ratio of male to female was 1.9:1.Twenty-seven(71.1%)patients suffered mild brain injury,4(10.5%)patients moderate brain injury and 7(18.4%)patients severe brain injury.In non-comatose patients,some patients suffered motor control disorder as hemiplegia,aphasia,cognitive disorder,Rom limitation,muscle tone disorder,muscle weakness,sitting balance disorder and standing balance disorder respectively.Thirty-six(94.7%)patients couldn't take care of themselves independently.Conclusion The function disorder of traumatic brain injuries occurred in earthquake had some particular characteristics.it's necessary to establish a rehabilitation system for the effectire rehabilitation management and treatment according tO the patients'characteristics.
2.Rehabilitation of Hemiplegic Patient with Bilateral Hemianopia:One Case Report
Qiang GAO ; Jianhua LIU ; Chengqi HE ; Min GUAN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(2):130-131
Cerebrovascular diseases can lead to hemiplegia,hemiparaesthesia and hemianopia.However,patients with poor eyesight resulting from bilateral cerebral infarction are rare.The authors reported here the rehabilitation assessment and treatment of one case with hemiplegia and poor eyesight resulting from bilateral cerebral infarction.According to the poor eyesight of the patient,a rehabilitation program which was different from common program was designed,and the patient can walk independently and achieve basic activities of daily living independence underlying the treatment of the new rehabilitation program.The attention should be paid on the variant rehabilitation treatment process depending on variant condition of patients.
3.Analysis of Risk Factors of Recurrent Acute Pancreatitis
Xiaoling KUAI ; Haifang DING ; Jianfeng ZHANG ; Zhaoxiu LIU ; Chengqi GUAN ; Zhenbiao MAO
Chinese Journal of Gastroenterology 2016;21(12):729-732
Background:Recurrent acute pancreatitis(RAP)is a special type of acute pancreatitis(AP). Finding the cause is the key to avoid the recurrence of RAP. Aims:To investigate the risk factors of RAP. Methods:The clinical data of 43 patients with RAP and 130 patients with only one time AP(control group)were retrospectively analyzed. Risk factors of recurrence of RAP were analyzed. Results:Univariate analysis showed that no significant differences in etiology,severity, serum levels of cholesterol,calcium,white blood cell count,amylase,ALT,AST,total bilirubin,direct bilirubin and C-reactive protein were found between RAP group and control group(P > 0. 05). Serum triglyceride level,blood glucose level and CT score in RAP group were significantly higher than those in control group(t = 3. 260,P < 0. 05;t = 2. 720, P < 0. 05;t = 2. 162,P < 0. 05). Logistic regression analysis demonstrated that serum triglyceride level,blood glucose level and CT score were risk factors of RAP(oR = 1. 86,95% CI:1. 05-3. 68,P = 0. 03;oR = 1. 23,95% CI:1. 01-1. 50,P = 0. 04;oR = 2. 46,95% CI:1. 00-6. 03,P = 0. 04). Conclusions:The recurrence of RAP is related with serum triglyceride level,blood glucose level and CT score.
4.Expression and clinical significance of CtBP2 in human esophageal squamous cell carcinoma
Chengqi GUAN ; Mingbing XIAO ; Cuihua LU ; Wenkai NI ; Feng JIANG ; Runzhou NI
Chinese Journal of Clinical Oncology 2015;42(22):1081-1084
Objective:To explore the expression of C-terminal binding protein 2 (CtBP2) in human esophageal carcinoma and its relationship with clinicopathological parameters and survival. Methods:The expression levels of CtBP2 in eight cases of fresh frozen specimens of esophageal squamous cell carcinoma (ESCC) and the adjacent esophageal tissues were detected by Western blot. Immuno-histochemistry was used to detect CtBP2 expression in 90 samples of ESCC tissues and adjacent non-tumor tissues. Based on patient in-formation and follow-up data, the correlation of CtBP2 expression with patients' clinicopathological characteristics and overall survival was further evaluated using Fisher's exact test and Kaplan-Meier method, respectively. Results: Immunohistochemistry and Western blot analysis showed that CtBP2 expression in tumor tissues was higher than that in adjacent non-tumor tissues. CtBP2 expression was significantly correlated with histologic grade (P=0.002) and depth (P=0.032). Kaplan-Meier analysis demonstrated that high CtBP2 ex-pression was correlated with a short survival time. Conclusion:CtBP2 expression was upregulated in ESCC tissues, indicating that it may play a role in the oncogenesis and development of ESCC.