1.Analysis of the effect of laparoscopic salpingostomy in the treatment of infertile caused by hydrosalpinx
Chinese Journal of Primary Medicine and Pharmacy 2013;20(14):2154-2156
Objective To analyze the effect of laparoscopic salpingo.stomy in the treatment of infertile caused by hydrosalpinx,and explore the reasonable treatment method for improving pregancy rate.Methods 130 infertile women with hydrosalpinx were treated with salpingostomy firstly,some unsuccessful cases were treated with salpingectomy.The pregnancy rate between successfully salpingostomied patients and unsuccessfully salpingostomied patients was also compared.Results 85 cases were salpingostomied successfully,the successful rate was 65.4%,among these patients 40 received IVF-ET,there was no difference in the natural pregnancy rate between singly hydrosalpinx (17.9%) and double hydrosalpinx(16.7%) (x2 =0.06,P > 0.05),but the artificial pregnancy rate in single hydrosalpinx(70.0%) was higher than double hydrosalpinx (35.0%) (x2 =4.912,P < 0.05).Among 45 unsuccessfully salpingostomied patients,14 cases underwent salpingectomy,all patients received more than two times of IVF-ET treatment,the pregnancy rate in salpingectomied patients (21.4%) was higher than unsalpingectomied (3.2%) (x2 =3.946,P < 0.05).The artificial pregnancy rate of successfully salpingostomied patients (52.2%) was higher than unsuccessful patients (21.4%) (x2 =4.055,P < 0.05).Conclusion Salpingostomy can raise the pregnancy rate (natural or artificial),it is beneficial to do salpingectomy for unsuccessfully salpingostomied patients who want to receive IVF-ET.
2.Analysis of the Factors Related to the Prognosis of Chronic Cervicitis After Electronic Burn Therapy
Chengkang XU ; Zhuoxian MEI ; Jianzhao HUANG ; Wenting ZHENG
Journal of Sun Yat-sen University(Medical Sciences) 2001;22(3):225-227
【Objective】Finding the relative factors that influence the effect of electronic burn therapy in chronic cervicitis.【Methods】Some pathogens have been detected in 176 cases of patients with chronic cervicitis who have underwent electronic burn therapy.Some possible relative factors that influence the effect of electronic therapy in chronic cervicitis have been analysed.【Results】The relative factors include the degree of cervical erosion,character of cervical grume,degree of vaginal cleanness;puriform cervical grume,poor vaginal cleanness have higher positive rate of all kinds of pathogens.【Conclusion】Some relative pathogens should be detected and eliminated before electronic burn therapy in patients with chronic cervicitis.At least,those patients who present higher degree of cervical erosion,puriform cervical grume,poor vaginal cleanness should be treated with drug until these indexes improve before electronic burn therapy.
3.Research on the differential diagnosis of phlegm and blood stasis pattern and qi deficiency and blood stasis pattern in stable angina pectoris based on coronary artery CT angiography radiomics
Dongsheng WEI ; Jiajie QI ; Xiaosheng LIU ; Luzhen LI ; Han LI ; Yuting LIU ; Chengkang DENG ; Xu DAI ; Baoying ZHAO ; Zhe ZHANG
Journal of Beijing University of Traditional Chinese Medicine 2024;47(4):545-554
Objective To establish a differential model of phlegm and blood stasis pattern and qi deficiency and blood stasis pattern in stable angina pectoris using radiomics.Methods A total of 91 patients with stable angina pectoris who underwent coronary artery CT angiography in Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2021 to January 2022 were collected,including 47 cases of phlegm and blood stasis pattern and 44 cases of qi deficiency and blood stasis pattern.The patients were divided into train set(64 cases)and test set(27 cases)according to the ratio of 7∶3 by stratified random sampling method.3D-slicer software was used to extract the radiomics features of pericoronary adipose tissue(PCAT)images.Principal component analysis was used to visualize the distribution of radiomics features of pattern of phlegm and blood stasis and pattern of qi deficiency and blood stasis.The least absolute shrinkage and selection operator regression analysis and support vector machine decreasing feature elimination were used for feature selection.The multinomial logistics regression was used for model construction.The receiver operating characteristic(ROC)curve was used to verify the model in the train set and the test set to evaluate the effectiveness of the radiomics features in differentiating phlegm and blood stasis pattern and qi deficiency and blood stasis pattern.Finally,Spearman coefficient was used to analyze the correlation between the differential features and clinical physicochemical data.Results A total of 837 radiomics features were extracted from PCAT images by 3D-slicer software.In the principal component analysis,PC1 and PC2 explained 77.9%and 8.1%of the total variance,respectively,and there was a relatively obvious separation trend between the two pattern groups.After feature screening,7 radiomics features were used to construct the differential model of phlegm and blood stasis pattern and qi deficiency and blood stasis pattern.The area under the ROC curve(AUC)of the differential model was 0.844 in the train set and 0.834 in the test set.Spearman correlation analysis showed that the differential features were significantly correlated with cTnI,neutrophil,triglyceride,total cholesterol,and leukocyte.Conclusion The CT radiomics model based on PCAT has a high discrimination efficiency for stable angina pectoris with phlegm and blood stasis pattern and qi deficiency and blood stasis pattern.