1.Role of Working Memory in Comprehension in Aphasia (review)
Jian YANG ; Hong WANG ; Zhuoming CHEN ; Chengju LIAO ; Zhenping LIN
Chinese Journal of Rehabilitation Theory and Practice 2014;20(11):1008-1010
In recent years, the relationship between working memory and language comprehension received more and more attention by many researchers, especially those of psychology and pedagogy. This article reviewed the researches on the working memory and language comprehension disorder in aphasia, including the theoretical model of working memory, assessment and brain positioning, etc., and discussed the process of working memory and comprehension disorder in rehabilitation.
2.Nano-carbon tracer technology mapping lymph node dissection in laparoscopic mid-low rectal cancer resection
Xiangan TIAN ; Chengju YANG ; Yuansheng DING ; Jianguo HUANG ; Liguang YANG ; Qinli SUN ; Naiqing LIU
Chinese Journal of Current Advances in General Surgery 2017;20(3):188-192
Objective:To investigate the clinical application value of nano-carbon tracer technology in lymph node dissection and postoperative pathological examination in laparoscopic mid-low rectal cancer resection.Methods:Fifty-two patients with mid-low rectal cancer were randomly divided into experimental group (n=27) and control group (n=25).Before surgery,the Nano-group were injected nano activated carbon suspension liquid under the mucosa.Both groups were accepted the same principles of open colorectal cancer radical surgery.The total number of lymph nodes,number of tiny lymph nodes,number of black dye and number of metastasis lymph node confirmed by pathology in the two groups were statistical analysised.Results:There were 905 pieces of lymph node seized in two groups toally,including (20.67 ± 5.751) medals in Nano-carbon group and (13.88 ±4.466) medals in control group.Lymph node number in nano carbon group was more than control group (P<0.01).Nano-carbon group seized 113 tiny lymph nodes,significantly higher than 49 in the control group (P<0.05).The metastasis rate of lymph node was no significant difference in the two groups (P>0.05).Nano-carbon group seized lymph node metastasis was no significant difference in the rate of the control group (P>0.05).Nano-carbon group seized 341 black dyed lymph nodes and 217 not black dye lymph nodes.And 67 cases of metastasis lymph nodes in Black dye lymph nodes,15 cases of metastasis lymph nodes in not the black dye lymph nodes.The metastasis rate of black dye lymph node was higher(P<0.01).Conclusions:Nano-carbon tracer technique can guide the surgeon to accurately lymph nodes dissection during the operation,and can add to the number of lymph nodes in the postoperative surgical specimens,improve lymph nodes in patients with colorectal cancer radical seized quantity.Nano-carbon tracer technique can ensure the accuracy of the pathological staging,there was important clinical significance to lymph node dissection in Mid-low colorectal cancer,which provide an important basis for the development of postoperative adjuvant therapy programs.
3.Comparative study on the nutritional status effect of two different parenteral nutrition solutions in early preterm infants
Kuilin LYU ; Liyan WANG ; Wang YANG ; Chengju WANG ; Chao LI ; Zhangya YANG ; Yuping ZHANG
International Journal of Pediatrics 2014;41(6):648-651
Objective To compare the effects of two different parenteral nutrition solutions on nutritional status of premature infants,such as the early physical,serum prealbumin,retinol binding protein and albumin.Methods We collected 61 cases of premature infants in neonatal intensive care unit of the Third Military Medical University Xinqiao Hospital,which were divided into 2 groups of traditional parenteral nutrition (TTPN) and early parenteral nutrition (ETPN).Group TTPN geted 6% paediatric compound amino acid 0.5 g/(kg·d) at24 hours after birth,daily increasing 0.25 ~0.5 g/(kg·d),up to 3.0 g/(kg·d).The 20% long-chain fat emulsion 0.5 g/(kg ·d) was applied at 3 days after birth,daily increasing 0.25 ~ 0.5 g/(kg·d),up to 3.0 g/(kg·d).Group ETPN get 6% paediatric compound amino acid 1 g/(kg·d) at 12 ~24 hours after birth,daily increasing 0.5 g/(kg·d),up to 3.0 ~ 0.5 g/(kg· d).The 20% long-chain fat emulsion 0.5 ~ 1.0 g/(kg·d) was applied after 24 hours after birth,daily increasing 0.5 g/(kg· d),up to 3.0 g/(kg· d).We calculate calorie and amino acid intake of the two groups,and compared the weight,length,head circumference growth,serum prealbumin,retinol-binding protein and albumin levels of the two groups.Results The amino acid and total caloric intake of Group ETPN were significantly higher than those of Group TTPN (P < 0.05).No statistical differences in the albumin,prealbumin,and retinol binding protein level of the two groups at birth (P > 0.05).However,the prealbumin and retinol-binding protein level of group ETPN significantly higher than those of Group TTPN (P < 0.05) at 7 days after birth.Conclusion Early parenteral nutrition in early life can effectively improve physical growth and nutrient metabolism status of premature infants.Prealbumin and retinol-binding protein are sensitive to evaluate the protein nutritional status in premature infants.
4.Effect analysis of influenza vaccination among medical staff
Chengju WU ; Xiuxia ZHENG ; Fei SUN ; Zhe TANG ; Hua XING ; Jie YANG
Chinese Journal of Practical Nursing 2008;24(17):57-59
Objective The purpose d this investigation was to evaluate the effect d influenza vaccination among medical staff. Methods We chose 134 medical staff who worked in out-patient department and the wards and received influenza vaccination as the inoculation group, 135 medical staff who did not receive influenza vaccination as the non-inoculation group. Investigation with questionnaires was carried out in the two groups 3 months after vaccination. Results The incidence rate of influenza-like disease in the observation group and the control group was 11.2% and 18.5% respectively. The protective rate was 39.46%. The average illness process of influenza-like disease in the observation group and the control group was 1.73 days and 2.96 days. The percent of patients with no medication, one kind of drug medication and two kinds of drag medication was 46.7%, 33.3% and 20.0% in the observation group and 32.0%, 8.0% and 60.0% in the control group. Conclusion Influenza vaccination exerted protective effect for medical staff and other people at high risk of emergency.
5.The expression of BMP-2 mRNA of rat osteoblast cell sheets cultured with ascorbic acid
Chengju ZHOU ; Jianjiang ZHOU ; Hong YANG ; Jiufeng MAO ; Xiao ZENG ; Yuanyuan JIA ; Yuting WANG ; Qiang DONG
Journal of Practical Stomatology 2015;(3):305-308
Objective:To study the effects of ascorbic acid on BMP-2 mRNA expression of osteoblast cell sheets.Methods:Rat os-teoblasts were primaryly cultured and identified;osteoblast cell sheets were built by physical scraping method in vitro;the osteoblast cell sheets were cultured with 1 5,50 and 85 mg/L ascorbic acid for 1 and 2 weeks respectively,and the expression of BMP-2 mRNA of the cell sheets was detected by RT-qPCR.Results:The obtained cells were conformed to be osteoblasts.The osteoblast cell sheets could be rolled into tube in vitro.The expression of BMP-2 mRNA of osteoblast cell sheets in experiment group,whether in week one or week two was higher than that in control group,50 mg/L group showed the highest expression(first week P <0.05;second week P>0.05);the expression of any group in week two was higher than that in week one(P <0.05).Conclusion:Ascorbic acid may pro-mote the expression of BMP-2 mRNA in osteoblast cell sheets.
6.Effect of Lee-Silverman voice treatment on electroglottography parameters and speech function in Parkinson's disease patients with dysarthria
Chengju LIAO ; Jinmei PAN ; Shaobin CHEN ; Chenghong LUO ; Jian YANG ; Zhiqiang HUANG ; Jiaxing LUO ; Guiyang ZHANG ; Yuhan ZHANG
Chongqing Medicine 2024;53(9):1328-1332
Objective To explore the effect of Lee-Silverman voice treatment (LSVT) on language re-habilitation of dysarthria in Parkinson's disease (PD).Methods A total of 84 patients with PD dysarthria ad-mitted to our hospital from February 2019 to February 2022 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 42 cases in each group.The control group received routine speech rehabilitation training,and the observation group re-ceived LSVT for four weeks.The scores of Western Aphasia Battery (WAB) and Aphasia Quotient (AQ) be-fore and after intervention were compared between the two groups,and the differences of electroglottographic parameters such as jitter,F0,shimmer,normalized noise energy (NNE) and harmonic noise ratio (HNR) were compared between the two groups.Results Before intervention,there was no significant difference in WAB scores (listening comprehension,repetition,spontaneous speech,naming) and AQ scores between the two groups (P>0.05).After intervention,the above scores of the two groups were significantly improved,and the observation group was higher than the control group,the difference was statistically significant (P<0.05). Before intervention,the jitter,F0,shimmer,NNE,HNR of vowels "a""i""u" in the two groups were not sta-tistically significant (P>0.05).After intervention,the above-mentioned electroglottic parameters of the two groups were significantly improved.The jitter and NNE of vowels "a""i""u" in the observation group were lower than those in the control group,and the HNR was higher than that in the control group,the differences were statistically significant (P<0.05).Conclusion LSVT can improve the electroglottographic parameters and speech function of patients with PD dysarthria,and the language rehabilitation effect of PD dysarthria is obvious.