The left ventricular bands of isolated human heart were studied by microscopy, echocardi ography and gross anatomical method. The results indicate that the structures of the bands were those commonly observed in human heart. They could be classified into two types: myo-bands and tendinous bands. However, we could only differentiate the “bands whose” diameter was more than 1.5mm with Aloka-SSD720 echocardiograph (made in Japan). we suggest that the resolution of the instrument we used was too low, and this might be the main reason that the detection of left ventricular bands was much lower than the incidence, we classified these bands according to the adhering points and diameters of bands.In this paper, the forming factors of bands and their clinical significance are also discussed.

The effect of high dos; dexamethasone(5mg/kg wt, intravenous injection)to prevent and treat the secondary pathological damage of craniocerebral injury was studied in animal models of craniocerebral injury caused by high-velocity missiles in dogs.We observed ths physiological changes, analyzed the value of serum and. cerebrospinal fluid lactate dehydrogenase, estimated the permeability of blood brain barrier (BBB) and studied brain pathology by light and electron microscopy.The results suggest high dose dexamethasone can help to restore ths structure and function of BBB, protect brain cells as well as lessai the secondary pathological damage in tha respiratory and circulatory systems and reduce th production of lipoptrox-ides(LPO).

In order to provide an experimental evidence for clinical utility, we undertook a series of experimental studies of glucocorticosteroid to treat closed head injury and gun shot brain wound, For studies of closed injury in rats, there were four groups as follows: Group 1: methyl prednisone 30mg/kg (MPG); Group 2: dexamethasone 5 mg/kg (HDMG): Group 3: dexamethasone0.5mg/kg (LDMG); and Group 4: normal saline as a control group (CG) For study of gun shot wound of brain, The dogs were divided into three groups, Grup 1 (wound group, n=8); Group 2 (treated group, n=7) and group 3 (control group, n=7). After injury, the vital signs were observed, the water content of the brain and Even' s blue level were measured and the brain were examined under optical and electronic microscopy, All results proved that secondary traumatic edema in the animals used high dose glucocotricosteroid were much more slight

Physical constraints is a commonly protective medical measure in clinic. if lack of humanistic nurs-ing in the use of the process,then it will give the patient a physical,psychological and ethic issues. This paper sum-marized the research status of humanistic nursing and physical constraints and concluded the humanistic nursing measures before, during, and after physical constraints, and thus to provide a reference for the further implementa-tion of humanistic nursing.

Objective To investigate the relationship between cytoreduction outcome and staging of ovarian cancer with preoperative blood cell count.Methods The data of 148 ovarian cancer patients from January 2007 to June 2012 were analyzed retrospectively.Clinicopathological and blood cell count data were collected,and benign ovarian tumor group (n =96) as controls.Results Compared to the control group,there were significant differences in the number of white blood cells,neutrophils,lymphocytes,monocytes,platelets,neutrophil to lymphocyte ratio,and platelets to lymphocyte ratio in patients with ovarian cancer (P ＜ 0.05).The same results were also observed in advanced groups and early groups.While between optimal cytoreduction and suboptimal cytoreduction,there were significant differences in platelets,monocytes,neutrophil to lymphocyte ratio,and platelets to lymphocyte ratio (P ＜ 0.05).Conclusions The cytoreduction outcome and pathological staging of ovarian cancer are closely related to the preoperative blood cell count.Blood cell count is important for the identification of benign and malignant ovarian tumors,cytoreduction outcome and the prediction of pathological staging,and may be of significance to the monitoring and prognosis of the disease.

Through expounding the connotation of clinical physicians'humanistic medicine practice ability,this paper pointed out that building the evaluation index system should abide by the four principles of systematicness,scientificity,guidance and feasibility.Constructing the evaluation index system of clinical physicians' humanistic medicine practice ability included 4 first-level indicators,13 second-level indicators and 47 third-level indicators,which is beneficial to promoting the physicians' humanistic medicine practice ability and is conducive to improve the human resource evaluation and management of hospitals.

Objective: To observe the clinical effects on advanced esophageal cancer by combined Xihuang Pill with chemotherapy. Methods: Dividing 35 advanced esophageal cancer cases randomly into two groups: 18 cases in the treatment group and 17 cases in the control group. Cases in the control group were treated by nedaplatin 40mg/m2,d1,2; 5-Fu400mg/m2,d1-5; CF200 mg/m2,d1-5. While the treatment with Xihuang Pill combined. The difference of quality of life, hematological toxicity, efficacy and symptoms between the two groups was observed. Results: The quality of life, remission rate of some symptom in the treatment group were much better than the control group, and the hematological toxicity and efficacy were the same. Conclusion: Xihuang Pill could improve the quality of life of advanced esophageal cancer patient, and alleviate some symptoms.

Objective To explore whetherthere exists Schwann-cell derived neurotrophic factor (SDNF) receptor in peripheral nerve. Methods SDNF binding sites in rat sciatic nerve were studied using 125 Ⅰ-SDNF as a radioligand (radioligand binding assays). Results There exists SDNF specific binding sites in peripheral nerve,and the specific binding sites have the following characteristics:①The equilibrium dissociation constant (kd) was (93.11?0.52) pmol/L.②The maximal binding capacity (B max ) of SDNF was (8.91?0.26)fmol/mg protein.③Saturation.④Kinetic studies revealed that the association rate constant (K 1) was (3.91?0.63)?10 7M -1 ?min -1 and the dissociation constant (K -1 ) was (3.38?0.54)?10 -3 min -1 .⑤Specific studies of SDNF binding sites showed that the binding sites were highly specific for SDNF. Conclusion SDNF receptor exists in the peripheral nerve and the peripheral nerve may be one of target tissues of SDNF.

Observations on the developement of pathological changes of rat brain, together with dynamic detection of CN- concentrations in blood and brain tissue and quantitive analysis of brain cytochrome oxidase activity, are carried out within 24 h after acute cyanide intoxication (4.5mg/kg i.p.) . The results indicate that in the cyanide poisoning with the dose under lethality (80%LD) , the pathological changes in rat brain appear, especially in cytochrome oxidase poorly- contained areas, including! 1 ) degeneration and necrosis of neurons and gliocytes; 2) degeneration, swelling and lysis of different cell projection components; 3) the myelinoclasis of myelinated nerve fibers. Those changes undergo a dynamic course divided into three phases: 1 ) the phase of metabolic disturbance; 2) of response to injury; and 3) of restoration. The authors consider that the acute poisoning displayed by the animal after NACN injection is directly caused by the intense inhibation of brain cytochrome oxidase; the secondary lesions of brain structure may be responsible for the manifestations such as trembling, unstable, and ataxia etc.occur later. The mechanisms of the brain pathological changes after cyanide intoxication are also disscussed.

The changes of immunoreactive TRH (TRH-ir) in cerebrospinal fluid (CSF) and plasma before and after acute traumatic head injury were determined with radioimmunoassay (RIA) on a feline model of acute experimental head trauma. The results showed that the concentrations of TRH-ir in experimental animals pre- and 2, 4, and 6h post-injury were 119.48?51.77, 460.71 ?178.72, 377.27? 139.33, and 280.17?110.46pmol/L in CSF, and 122.58?28.87,1158.89?163.18, 909.69?160.55, and 545.38?132.80pmol/L in plasma, respectively, while those in control animals measured at the corresponding time were 112.22?53.42, 105.36?49.64, 100.63?52.89, and 104.52?52.42pmol/L in CSF, and 113.57 ?25.79, 107.32?26.60, 119.84?31.53, and 117.21?28.95pmol/L in plasma, respectively. The contents of TRH-ir in CSF and plasma in the experimental group after traumatic head injury were significantly higher than those, in the control group (P