In the paper,we will deeply research sorts of ethical problems in medical genetics and their origins through a view of the human dual evolutions,and bring forward the viewpoint that any ethical problem can be originated from the conflict between human biological evolution and cultural evolution.Based on fully reasoning the relation between ethical problems in medical genetics and human evolution,the authors put forward a series of corresponding strategies to solve the ethical problems in medical genetics.

Cross-lingual strategy is a teaching methodology in which the mother tongue is employed as a reference or comparison.Based on the English teaching practices in China,this article explores the importance and significance of cross-lingual strategy in English classroom teaching from the perspectives of second language acquisition theory,contrastive linguistics and psychological linguistics.

For medical interpretation,medical students enjoy the advantages of professional knowledge.Based on the case of the Second Military Medical University,this paper elaborates on the necessity and reasonableness of opening the optional course of medical interpretation for medical students,and makes further exploration on the methods and strategies of cultivating medical interpreters in higher medical education from the perspectives of trainee selection,knowledge structure and course designing.

Objective To explore the effect of aconitine on serum zinc finger protein 41 and secreted protein acidic and rich in cysteine in ventricular septal defect model rats.Methods 80 ventricular septal defect model rats were randomly divided into two groups, experimental group ( n=40) were treated with 0.05 mg/kg aconitine via tail vein injection for 7 consecutive days;control group (n=40) were treated with normal saline via tail vein injection for 7 consecutive days.Then, the abdominal aorta blood of each rat was collected, and the contents of zinc finger protein 41 and SPARC in two groups were detected by Western blot and ELISA method,seperately.Results Western blot results showed that the expression of zinc finger protein 41 and SPARC in serum samples of experimental group were significantly lower than that of control group ( P<0.05 ) .ELISA results showed that the contents of zinc finger protein 41 and SPARC of experimental group was significantly lower than that of control group ( P<0.05 ), respectively.Conclusion Aconitine can decrease the expression of serum zinc finger protein 41 and SPARC in ventricular septal defect model rat.

Axilla ; Breast Neoplasms ; pathology ; surgery ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes ; pathology ; surgery

Animals ; Biocompatible Materials ; therapeutic use ; Bone Regeneration ; Bone Substitutes ; therapeutic use ; Bone Transplantation ; Collagen ; therapeutic use ; Guided Tissue Regeneration, Periodontal ; methods ; Humans ; Membranes, Artificial ; Periodontal Diseases ; surgery ; Polytetrafluoroethylene ; therapeutic use

Humans ; Myocardial Infarction ; diagnosis ; Takotsubo Cardiomyopathy ; diagnosis

Aging ; Animals ; Male ; Nitric Oxide ; metabolism ; Rats ; Rats, Sprague-Dawley ; Superoxide Dismutase ; metabolism ; Testis ; metabolism

Objective:To investigate the direct effect of different concentrations of hydrogen sulfide(H_2S)on neonatal rat myocardial cells by hypoxia injury during different time point,and the indirect effect of reoxygenation injury in order to analyze the protective role of H_2S on myocardial cells subjected to hypoxia/reoxygenation injury. Methods:Primary cultured myocardial cells from neonatal rats were randomly divided into 9 groups:Normal control group,Hypoxia NaHS 0 μmol/L group,100 μmol/L group,200 μmol/L group,400 μmol/L group and those groups subjected to hypoxia for 24 h,48 h and 72 h. Hypoxia/reoxygenation NaHS 0 μmol/L group,100 μmol/L group,200 μmol/L group,400 μmol/L group and those groups subjected to hypoxia for 24 h,48 h,72 h and then reoxygenation for 2 h. The number of survival cells were counted and the activity of lactate dehydrogenase(LDH)were measured respectively at each time point. Results:At the same time point of 24 h,48 h,72 h hypoxia,the number of survival cells increased and the activity of LDH decreased in hypoxia NaHS treatment groups as compared with Hypoxia NaHS 0 μmol/L group(P<0.01). The protective role of Hypoxia NaHS 200 μand 400 μmol/L groups were better than NaHS 100 μmol/L group at 24 h of time poit(P<0.05～0.01). The number of survival cells by hypoxia/reoxygenation increased and the leakage of LDH from reoxygenation cells decreased in hypoxia/reoxygenation NaHS treatment groups as compared with hypoxia/reoxygenation NaHS 0 μmol/L group(P<0.01).Conclusion:NaHS 100 to 400 μmol/L had the protective effects on myocardial cells by hypoxia/reoxygenation injury. NaHS 200 to 400 μmol/L might offer the best protective effects on myocardial cells by hypoxia injury at 24 h.

Echocardiography plays an important role in diagnosing cardiac tumors and is helpful for subsequent treatment decision making.However,conventional echocardiography can hardly meet the clinical requirements of sufficient diagnosis,mostly due to the fact that it usually does little on identification of benign and malignant characters of tumors.Contrast echocardiography is a new technology using microbubbles as a contrast agent to trace the blood flow,which promotes the definition of endocardium lines and helps to reveal spaceoccupying abnormities in heart.Moreover,myocardial contrast echocardiography can be used to evaluate perfusions of intracardiac masses,and thus improves the accuracy of differential diagnosis enormously.