Humans ; Myocardial Infarction ; diagnosis ; Takotsubo Cardiomyopathy ; diagnosis

Arthroscopy ; methods ; Humans ; Knee Injuries ; surgery ; Shoulder Joint ; injuries

Chemical and Drug Induced Liver Injury ; Humans

Objective To evaluate the independent effect of premorbid statins on incident ischemic stroke severity and outcome at discharge.Methods We included consecutive patients with ischemic stroke and recorded demographic data,vascular risk factors,Oxfordshire Classification,the method of treatment National Institutes of Health Stroke Scale(NIHSS)score,previous statins treatment,and outcome discharge.We analyzed the data using univariate methods and a logistic regression with the dependent variable of good outcome(Barthel Index,BI 95 to 100).Results A total of 185 individuals met study criteria:57 patients were on statins agents prior to admission and 128 were on no statins.Pretreatment with statins was associated with lower presenting median NIHSS(6.0 vs 13.0,P

Adult albino mice were starved for 66 to 120 hours and the liver was examined forphosphatases, glycogen and ribonucleic acid. Alkaline phosphatase was found to increasemoderately while acid phosphatase showed no significant change. Both glycogen andribonucleic acid disappeared completely. The periphery of the hepatic lobule often stainedmore deeply than the centre due mainly to the conspicuous staining of the cell borderand of the Kupffer cells. The duration of starvation had no infiuence on the amountof both alkaline and acid phosphatases. In the refeeding experiment, mice starved for 48 to 72 hours were refed and werekilled 11 to 72 hours after subjecting to normal diet. The liver cells contained even greateramount of glycogen than in control animals. The restoration of ribonucleic acid was onlypartial. Both alkaline and acid phosphatases showed variable activities in the refeedingliver. The liver cells usually swelled and became rarefied, the sinusoids were very in-conspicuous. The swelling and rarefation of liver cells were caused by the accumulationof glycogen during refeeding. Three days refeeding did not bring this histological pictureto that of the control liver.

Objective To explore the influencing factors of pharmacotherapy effect of ectopic pregnancy and nursing measures. Methods 569 patients with ectopic pregnancy using pharmacotherapy were retrospectively analyzed in our department. Results Among 569 patients,423 patients gained successful treatment,while 146 patients failed the treatment.Blood β-HCG level,diameter of ectopic mass showed by B ultrasound were influencing factors of pharmacotherapy effect.The higher β-HCG level,the longer diameter of ectopic mass showed by B ultrasound,the lower success rate of pharmacotherapy.The patients with β-HCG＜1000 mIu/ml,diameter of ectopic mass showed by B ultrasound less than 1 cm at admission acquired higher success rate of pharmacotherapy. Conclusions Patients with ectopic pregnancy who select conservative medication should be given pertinent psychological nursing,rigorous monitoring of disease condition and adverse reaction of drugs and timely and effective nursing measures,so that patients can get better nursing effect.

Objective To explore the correlation of infants with asthma and food allergens,to povide the basis for early prevent the development of asthma.Methods The U-niCAP-100 automatic detection system was used to check the common food allergens in serum of 79 infants with asthma and 68 healthy children of the same age.Results The positive rate of serum total IgE in the group of asthma was 64.6％,significantly higher than the healthy group (45.6％)(P＜0.01).The positive rate of serum SIgE was showed that:the mainly food allergens of the asthma group was milk(63.2％)and whole egg(26.3％)which were,significantly higher than the healthy group(36.8％,14.7％)(P ＜ 0.01 and P ＜ 0.05).Conclusion Asthma of infant had close relation with the food allergens.Early avoid food allergens had an important role in preventing the development in low-age children with asthma.

Objective To investigate the relationship between gestational hypothyroidism and preeclampsia.Methods A retrospective study was conducted on 1 776 patients with gestational hypothyroidism,who gave birth in the International Peace Maternity & Child Health Hospital of China Welfare Institute,Shanghai Jiaotong University School of Medicine from January 2013 to December 2014.They were divided into three groups,including Improving Group (n=1 469),Progressing Group (n=133) and Remaining Group (n=174),based on their thyroid function at the first and third trimesters.Levels of thyroid hormones in the first and third trimesters were analyzed.Incidences of preeclampsia in those patients were calculated.And the correlation between thyroid function and incidence of preeclampsia was analyzed.T-test,Mann-Whitney U test,Chi-square test,variance analysis (SNK method) and Kruskal-Wallis H test or Logistic regression were performed for statistical analysis.Results (1) There were no statistical differences in age,gravidity and parity among the three groups.The pregestational body mass index in Progressing Group was lower than that in Improving group (21.1 ±2.9 vs 21.8±2.8,P＜0.05).(2) In the first trimester,the level of thyroid stimulating hormone (TSH) in Remaining Group was higher than those in Improving and Progressing Groups [(4.21 ± 1.69) vs (3.77±.3.03) and (2.00±0.57) mU/L,F=27.635,P＜0.01],and that in Improving Group was higher than that in Progressing Group (P＜0.05).The level of free thyroxine (FT4) in Progressing Group was higher than those in Improving and Remaining Groups [(16.18±9.67) vs (14.58± 1.71) and (14.54± 1.74) pmol/L,F=16.188,P＜0.01].In the third trimester,the TSH level in Remaining Group was higher than those in Improving and Progressing Groups [(5.07±0.86) vs (2.57±0.77) and (4.31 ±0.87) mU/L,F=28.986,P＜0.01],while the TSH level in Improving Group was higher than that in Progressing Group (P＜0.05).No statistical differences in FT4 levels (in the third trimester) and positive rates of thyroid peroxidase antibody (TPOAb) Were observed in the three groups.(3) Blood pressures (including diastolic and systolic blood pressures) in the first trimester and diastolic pressures in the third trimester showed no significant differences among the three groups.Systolic pressure of Improving Group in the third trimester was lower than that of Progressing Group [(119.4± 11.9) vs (121.8± 14.2) mmHg,P＜0.05,1 mmHg=0.133 kPa].(4) The incidence of preeclampsia in Progressing Group was higher than those in Improving and Remaining Groups [7.52％ (10/133) vs 1.29％ (19/1 469) and 3.45％ (6/174),x2=26.646,P＜0.01],and the incidence in Progressing Group was higher than those in Remaining and Improving Groups (both P＜0.05).The incidence of severe preeclampsia in Progressing Group was higher than that in Improving Group [6.02％ (8/133) vs 0.41％ (6/1 469),P＜0.05].There were no significant differences in incidences of mild preeclampsia among the three groups.(5) After adjusting for age,body mass index,gravidity and parity,the risk of severe preeclampsia in Improving Group was lower than that in Remaining Group (OR=0.233,95％CI:0.057-0.946,P＜0.05).Conclusions By improving thyroid function in pregnant women with hypothyroidism,the risk of preeclampsia,especially severe preeclampsia,could be reduced,which could improve maternal and neonatal outcomes.

ObjectivesTo observe correlation between serum vitamin A status and prevalence or severity of NRDS. MethodsRecruited into this study were 166 preterm infants admitted to our neonatal department. The serum concentration of vitamin A was measured, and the prevalence of NRDS at different levels of vitamin A was compared. According to the clinical manifestation and X-rays, there were 30 infants diagnosed as NRDS. Another 30 patients from the rest 133 infants without NRDS were randomly selected as control group according to the gestational ages, then the difference between NRDS group and control group were observed according to gestational ages. The 30 preterm infants with NRDS were divided further into mild group (in-cluding stagesⅠandⅡ,n=18) and severe group (including stageⅢ andⅣ,n=12) according to ifndings chest X-ray, then the difference between these two groups were observed.ResultsIn the 166 preterm infants recruited, 65/166 had serum vitamin A lower than 0.35 μmol/L, in which 14/65 (21.54%) were NRDS patients. Another 93/166 patients had serum vitamin A ranged from 0.35 μmol/L to 0.7 μmol/L, in which 15/93 (16.13%) were NRDS patient. The rest 8/166 had serum vitamin A higher than 0.7 μmol/L, in which 1/8 (12.50%) were NRDS patient. However, the differences between each two groups were not signiifcant. When gestational ages ranged from 34 to 37 weeks, the serum concentrations of vitamin A of NRDS group were lower than that in controls (P<0.05). No signiifcant difference between the serum concentrations of vitamin A and the severity of NRDS were ob-served (P>0.05).ConclusionsThe prevalence of NRDS for those preterm infants lacking of vitamin A was tended to increase. And the late preterm infants (34 w≤ GA <37 w) with vitamin A deifciency are prone to NRDS.