Chloasma is a kind of skin disease with pigmentation on the face, which can be frequently seen in child-bearing age women. The disease is caused by Zangfu dysfunction, Qi and blood deficiency. For women, the generation of chloasma is closely related to their menstruation. Regulating the menstrual function with traditional Chinese medicine and balancing the body's internal environment can be very useful for achieving the balance between Yin and Yang within Zangfu, and regulating Qi and blood, which will not only desalt pigment, but also can improve the symptom related to menstruation with low recurrence rate after drug withdrawal. This method can be used alone or with other methods in clinic, has achieved significant effect.

Objective To investigate the effect of midazolam as premedication on stress response in patients undergoing cervical plexus block.Methods Sixty female patients undergoing selective thyroid surgery were equally randomized into groups of A and B.The patients in group A were intramuscularly injected midazolam 0.08 mg/kg before cervical plexus block and those in group B were not as the controls.Cervical plexus block was performed with 20 ml mixeture of 1% lidocaine and 0.25% ropivacaine 20 min later.BP and HR were recorded,rate-systolic pressure product (RPP) was calculated,and serum glucose(Glu),cortisol (Cor) and angiotensin Ⅱ (AT-Ⅱ) were detected before enter(T_0),before cervical plexus block(T_1),at 5 min(T_2),15 min(T_3) and 25 min(T_4) after cervical plexus block injection.Results In group B BP,HR,RPP,Glu,Cor and AT-Ⅱ all higher at T_1-T_4 than those at T_0 BP,HR,RPP,Glu,Cor and AT-Ⅱ were all lower in group A than those in group B at T_1-T_4 (P<0.05).Conclusion Intramuscularly premedication with midazolam is effective in reducing stress response in patients undergoing cervical plexus block.

In China, medical system reforms have made an obvious achievement in recent years .However, lots of urgent problems still exist.Doctors are not satisfied with their working environment.The high-pressure job with low remuneration reduces doctors'enthusiasm for work.Meanwhile, both the threat to personal safety and disrespect from patients bring negative effects to doctor's physical and mental health .The main factors causing this situation include the leaky health care system , the incomplete health -care legislation, the misleading reports and the poor medical knowledge of patients .Therefore, some countermeasures should be taken to solve problems mentioned above and the construction of medical ethics should be strengthened at the same time .

Questionnaire survey of case teaching was conducted among medical marketing majors,the results showed that case method was widely used in the teaching for medical marketing majors and was approved by most students,however,deficiencies still existed including lack of required teaching skills,outdated teaching concept,low-quality cases,inappropriate teaching methods,few participation,etc.To solve these problems,during the preparation and implementation of case teaching,teachers must update their teaching concept,participate in more training programs,improve case qualities,reengineer case activities and evaluate the effects at each phase.

Spinal cord injury is a common clinical disease .Cell apoptosis is one of important pathogeneses for spinal cord in-jury, and apoptotic gene plays a very important role in apoptosis on spinal cord injury .Chinese medicine for blood-activating and stasis-dissolving has a good therapeutic effect for spinal cord injury by reducing inflammation , inhibiting apoptosis and improving microcircu-lation.In this paper, we review the research of chinese medicine for activating blood and resolving stasis during the regulation of apoto -sis gene in spinal cord injury based on related documents in the recent five years .

Objective To discuss the clinical efficacy and mechanism research progress of acupuncture-moxibustion in treating toothache, for providing better treatment methods and clinical evidence.Method Taking “toothache”, “acupuncture”, “moxibustion”, “acupoint” as the key terms, clinical research literatures about acupuncture-moxibustion in treating toothache during the recent 10 years were retrieved by using computer, and were then arranged and analyzed.Result There is a variety of acupuncture-moxibustion methods in treating toothache, and the methods are effective.Conclusion Acupuncture-moxibustion therapy is effective in treating toothache, and deserves a large-sample multi-centered randomized research.

Objective To compare the clinical effects between simple debridement and debridement and interbody fusion and internal fixation for the treatment of children with spinal tuberculosis.Methods 120 cases of children with spinal tuberculosis,were divided into control group(n =60)and observation group(n =60)according to surgical treatment.The control group was administrated with conventional simple debridement treatment,the observation group was administrated with debridement and interbody fusion and internal fixation,the efficacy and quality of life level of two groups of children were compared after treatment.Results The total effective rate of the observation group was 93.3%,which was significantly higher than 73.3% of the control group(χ2 =7.69,P <0.01);The blood loss,operative time,postoperative complication rate of the observation group were (83.47 ±16.35)mL,(35.38 ± 12.34)min and 6.7%,respectively;which in the control group were (165.12 ±22.31)mL,(62.15 ±21.63)min and 21.7% respectively,the difference were statistically significant(t =19.95,20.34,χ2 =8.17,all P <0.05).The adverse reactions(loss of appetite,pain in the spine)rate of the observation group was 8.3%,which was significantly lower than 30.0% of the control group(χ2 =9.02,P <0.05).Conclusion The comparison with conventional simple debridement therapy,the use of debridement over interbody fusion and internal fixation is effective on treatment in children of spinal tuberculosis,children can speed up the recovery with fewer complications,which should be widely applied.

Population genetic data of the STR D13S325 locus in a sample of 216 unrelated individuals of Han population in Wuhan was studied with the method of PCR. 11 alleles and 30 different genotypes were observed.There is no significant deviation from the Hardy Weinberg equilibrium.The DP value was 0 9292,PE 0 6137 and PIC 0 7755.The results of study of 200 meiosis showed no mutation.The results prove that this STR Locus is useful in the forensic sicence practice in Han population in Wuhan.

Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents ; adverse effects ; therapeutic use ; Brain Neoplasms ; secondary ; Carcinoma, Non-Small-Cell Lung ; drug therapy ; secondary ; Exanthema ; chemically induced ; Female ; Humans ; Liver Neoplasms ; secondary ; Lung Neoplasms ; drug therapy ; pathology ; Male ; Middle Aged ; Neoplasm Staging ; Protein Kinase Inhibitors ; adverse effects ; therapeutic use ; Quinazolines ; adverse effects ; therapeutic use ; Remission Induction ; Survival Rate ; Vomiting ; chemically induced

Objective To investigate the effect of adenosine on rats with acute renal failure(ARF) resulting from ischemia-reperfusion(IR).Methods The model of renal IR injury rats was induced by nipping bilateral renal pedicels of rats with non-traumatic forceps for 40 minutes.The first adenosine group was given adenosine 10 mg/kg intraabdominally at 2 hours before IR.The second adenosine group was given the same adenosine at 40 minutes after IR.Serum creatinine(Scr) levels,the proportion of apoptosis of renal tubular cells(RTCs) and the pathological changes of renal tissue were observed separately in every group at 2,6,12 hours after IR.Results 1.At 12 hours after IR,in IR group Scr levels and apoptosis of RTCs count were(198.56?13.35) ?mol/L and 26.50?2.07,which were increased significantly compared with sham group.In the first and second adenosine groups,they were(113.85?(12.90) ?mol/L),14.67?3.44 and(218.79?37.65) ?mol/L,20.83?5.27,respectively,and all of them were higher than those in sham group(all P0.05).Conclusions Adenosine which is given to rats with IR before IR may be an effective pharmacological agent for prevention and treatment of renal IR injury.The mechanism may be relevant to saving energy and reducing cellular apoptosis.