Medicine is a comprehensive discipline.Under the new situation,medical students are required to have integral knowledge and whole view.This article aims at evaluating the necessity of diagnosis and discusses the defects,causes and strategy in this respect.

OBJECTIVE:To discuss the disposal of essential oil in the preparation process of solid preparations containing Ligusticum chuanxiong and Angelica dahurica.METHODS:Based on pertinent literature in recent years,the disposal of essential oil in the preparation process of solid preparations containing Ligusticum chuanxiong and Angelica dahurica was discussed from aspects of chemical components,pharmacology and extraction process etc.RESULTS & CONCLUSION:It is necessary to combine research on preparation process with the pharmacological effect and pharmacodynamic action,and to formulate effective measures to control quality of the essential oil during the whole preparation process to facilitate a solution for the disposal of essential oil.

Teachers'quality is an essential factor to improve teaching,and nowadays,lack of medical English teachers has become a serious problem many medical colleges have to deal with in our country. While designing the cours "eMedical English Watching,Listening and Speaking" ,English teachers,relying on their advantages of oral communication in English,can learn more basic medical theories and knowledge,and can gradually be trained as qualified medical English teachers after several years'teaching practice.

Objective:To investigate the family history of congenital heart disease (CHD) in Chogqing for studying the genetic relation of CHD families. Methods:The materials were collected from the population survey about families with more than one members being CHD patients. Map pedigrees for high-risk families were made. The probands and the first and second grade relatives were asked to fill in questionnaires and the high-risk families were analyzed. Results:In the survey of 4387 families, there were 21 high-risk families in which the disease types of the relative patients were inconsistent with those of the probands, the coincidence being 33.33%(7/121).The incidence rates of the first and second grade relatives were 16.49%(16/78),1.89%(5/265) respectively and their difference was significant ( ? 2=27.73, P

To increase the identification of pharyngeal bursa invasive fungal disease with lower cranial nerve involvement, reduce the misdiagnosis and improve the awareness of invasive fungal disease. We report the clinical data of a case with lower cranial nerve involvement as the first manifestation and reviewed the related literature.
Aged ; Cranial Nerves ; pathology ; Female ; Humans ; Mycoses ; complications ; pathology ; Pharyngeal Diseases ; etiology ; pathology

HPLC was applied to content determination of active components——chlorogenic acid and baicalin in Qingkailing Injection.This method is simple,rapid,involves good reproducibility,and can be as a reliable determination method for the quality control of Qingkailing Injection.The test conditions are as follows:detection wavelength at 340 nm,ODS C-18 chromatocolumn of stainless steel(3.9?30cm),mobile phase using methanol-water-tetrahydrofuran(25:57:18).

Objective To investigate the effect of tirofiban hydrochloride in the treatment of coronary heart disease and its influence on homocysteine level.Methods 92 patients with coronary heart disease were selected as research subjects.They were randomly divided into the observation group and the control group,46 cases in each group.The control group was treated with anti-thrombotic,nitrates and other conventional western medicine.The observation group was treated with tirofiban hydrochloride based on the conventional treatment.Results The total effective rate of the observation group was 95.65%,which was higher than 82.61% of the control group,the difference was significant (χ2=4.039,P<0.05).And the homocysteine level in the observation group was (5.38±1.02)μmol/L,which was lower than (7.27±1.19)μmol/L in the control group,the difference was statistically significant (t=8.179,P<0.01).After treatment,the cardiac function CO level[(4.96±0.98)L/min],EF level[(62.48±11.16)%]and SV level[(86.37±11.47)mL]in the observation group were higher than those in the control group,the differences were statistically significant (t=2.271,2.954,2.911,all P<0.05).After treatment,the hs-CRP level[(4.25±1.32)mg/L]and Fib level[(3.14±0.73)g/L] in the observation group were lower than those in the control group,the differences were statistically significant (t=7.981,3.174,all P<0.01).ConclusionTirofiban hydrochloride in the treatment of coronary heart disease can effectively contribute to the reduction of homocysteine levels and alleviate atherosclerosis lesion progression,not only can reduce severity of myocardial ischemia and fibrinogen and high-sensitivity C-reactive protein levels,but also can reduce the thrombosis and inflammation produced by the degree of harm to the patients.

Human DAB2 interaction protein (DAB2IP) is a novel member of Ras GTPase-activating protein family. It interacts directly with disabled-2 protein (DAB2/DOC2) which suppresses growth of cancers derived from different tissues, including mammary, prostate and ovarian cancers. DAB2IP was identified as an immediate downstream effector mediated by DAB2/DOC2. DAB2IP and DAB2/DOC2 form a unique protein complex that has a negative regulatory effect on the Ras-mediated signal pathway. It is demonstrated that DAB2IP is a tumor suppressor gene inactivated by methylation in several cancers. This article reviews the structure and biological functions of DAB2IP gene as well as its potential roles in carcinogenesis and evolution.

Turner syndrome (TS) is the result of complete or partial deletion of an X chromosome. It is often associated with endocrine dysfunction such as thyroid dysfunction, growth and developmental disorders, glucose and lipid metabolism disor-ders, and so on. Long-term follow-up of children with TS should regularly monitor thyroid autoantibodies, thyroid function, blood glucose and blood lipids for early detection and intervention of the complications, in order to further improve the life quality of children with TS.

Objective To study the stress resistance of Rhodiola under freezing injury stress. Methods With R.kirilowii, R.crenulata, R.Algida and R.fastigiata as the experimental materials, the effects of freezing injury stress on emerging time, duration of seedling emergence, emergence rate, surviving rate, the activity of SOD and POD were observed by field test and experimental detection. Results Before seeding, the effect of freezing injury stress on R.kirilowii was the largest, and that on R.fastigiata was the least. When injury stress happened during seedling stage, surviving rate, increase of SOD and POD activities of R.kirilowii was the least, indicating the freezing injury was severe. R.fastigiata was the best in those indexes. The stress resistance of Rhodiola was as follows:R.fastigiata > R.crenulata > R.Algida > R.kirilowii. Conclusion R. fastigiata and R.crenulata are good choice in introduction and cultivation of Rhodiola in Gannan area of Gansu province, and R.fastigiata is the best.