Objective To observe the clinical curative effect of ginkgo dipyridolum injection for treatment of 96 patients with acute cerebral infarction. Methods 192 patients were divided into two groups, 96each: treated group and control group. Treated group patients was treated with ginkgo dipyridolum injection to intravenous drip, The control group patients was treated witht taushin injection. 2 weeks were 1 course. To observe and analyse the score、the clinical curative effect of dysneuria,the side effects after use the medicine. Results The clinical effective rate with ginkgo dipyridolum injection was 93.7%, the control group' s was 77.1%. The differences in the clinical effective rate between treated group and control group were significant (P < 0.05). Conclusions It is safe and has good effect to treat acute cerebral infarction with ginkgo dipyridolum injection. The clinical curative effect of ginkgo dipyridolum is better than tanshin injection's.

Objective To study the clinical characteristics of systemic lupus erythematosus in male patients.Methods Clinieal data of 52 male patients with systemic lupus erythematosus were studied retrospectively.Results The age of onset of the male patients varied greatly and were predominant at the age of 10～20.Male patients were more susceptible to nephritis and more serious.The antibodies such as anti-ANA,anti-Sm and anti-ds-DNA were closely related to the severity of lupus nephritis(P＜0.05 of P＜0.01).Conclusion There are certain characteristics in male SLE,such as age of onset,such as age of onset,clinical manifestations and specific antibodies.

Oncolytic adenovirus-mediated E1A gene therapy may be a useful therapeutic approach for cancer treatment.In addition to direct lysis,viruses also mediate exogenous tumor suppressor genes inducing antitumor efficacy.Vectors need further investigation to improve the targeting and effectiveness in vivo.

Diffuse large B-cell lymphoma (DLBCL) is the most common adult lymphoid malignancy accounting for 30 ％-40 ％ of all non-Hodgkin lymphoma (NHL).Young patients with high-risk DLBCL as a special group with poor clinical prognosis still can not receive standard treatment protocols in clinical practice at present.Conventional chemotherapy, combination of rituximab (R) to conventional CHOP chemotherapy, R-CHOP-like protocol, high-dose chemotherapy and autologous hematopoietic stem cell transplantation have not fully reversed the poor prognosis.This review focuses on the recent advances and future direction in the treatment of the young patients with high-risk DLBCL.

Adult ; Aged ; Biomarkers ; metabolism ; Case-Control Studies ; Hepatitis B, Chronic ; drug therapy ; Humans ; Middle Aged ; Treatment Outcome ; Vitamin D-Binding Protein ; metabolism ; Young Adult

Helicobacter pylori is closely related to many digestive system diseases,such as chronic gas-tritis,digestive ulcer,gastric mucosa associated lymphoid tissue lymphoma and gastric cancer,also leads to chil-dren with iron deficiency anemia,growth retardation,asthma,allergic diseases etc. So it is a key strategy to pre-vent and treat these diseases by eradicating Helicobacter pylori. Due to the increasing rates of antimicrobial resist-ance of clarithromycin and metronidazole,the eradication rate of standard triple therapy is 1ess than 80%in re-cent years. Especially in areas of high clarithromycin resistance and standard triple therapy have not been recom-mended as first-line therapy,it is necessary to investigate a new therapeutic strategy to improve the eradication rate of Helicobacter pylori. The new treatments for eradication of Helicobacter pylori in children is mainly based on sequential therapy,bismuth-based therapy,concomitant therapy and probiotics treatment. This article reviews the research progress of the new treatments in recent years.

Objective: To analyze the equity of benefit for inpatient services under the three basic medical insurance programs in China.Methods: Using the baseline survey data collected by China Family Panel Studies (CFPS) in 2010, and the two-part model was applied to explore whether the insured groups with different income levels had different aspects on inpatient rate and the compensation of hospitalization expenses in health insurance coverage.Results: There was no significant difference in the inpatient service utilization rate for different income groups, but the highest and second highest income groups reimburse more expenses than the lowest income group, that is 36.5% and 26.3%, respectively.Specifically, the income level and the compensation amount are not significantly correlated in the Urban Employer Medical Insurance (UEMI) program;the compensation amounts to be paid by urban residents are basically increasing with the increase of the income level;and there is a moderate discrepancy between the highest and the lowest income groups in the New Rural Cooperative Medical System (NCMS).Conclusion: The benefit equity is obviously fair in terms of inpatient service utilization rate, but the benefit degree increases for higher income groups, which shows that there are unfair inequalities related to the income at the level of reimbursement.In terms of program comparison, the benefit degree equity is higher for the UEMI program, followed by the URMI program and the NCMS program is the worst.Besides, the impatient rate and reimbursement amounts are significantly lower for NCMS program participants.The government should merge URMI and NCMS programs, actively promote the integration of basic medical insurance system by strengthening the construction of the medical assistance system and improving the system of catastrophic disease medical expenditure insurance in order to achieve better benefit equity.

The curriculum for general practitioner training does not include much knowledge on medical humanities except for medical ethics,which can not meet the requirement of general practitioners' defined duty.This article analyzes the necessity of adding social psychological skills to the training and assessment of general practitioners from the following aspects of the nature of general practitioners' duty,and the disadvantages of medical humanities education in current Chinese medical universities.Then the proposition of this system is also presented.

OBJECTIVE:To investigate the incidence,clinical features and influential factor of adverse drug events appeared in Zhuhai area.METHODS:246 cases with adverse drug events reported in our hospital from Jan.to Sep.in 2007 were analyzed statistically.RESULTS:Of the total drugs inducing adverse drug events(246 cases),anti-infectives took the lead(43.24%),which was related to its great variety,high application frequency and application range;78.05% were induced by intravenous infusion;41.12% were manifested as lesion of skin and its appendants;119(48.37%)failed to follow the direction of package inserts,of which,113 cases involved the use of anti-infectives.CONCLUSION:Medical workers should attach great importance to the acquisition of medication knowledge as well as the medication safety at each steps.

OBJECTIVE: To explore the characteristics and general pattern of adverse drug events(ADE) in Zhuhai area.METHODS: 311 ADE cases collected from Aug.2005 to Dec.2006 by Zhuhai workstation of Guangdong ARD Monitoring Center were statistically analyzed in respect of patients' age and sex,route of administration,category of drugs involved,ADR-involving organs/systems and clinical manifestations etc.RESULTS: The antiinfective drugs showed highest incidence rate of ADE,which caused ADE in 213 cases(68.49%).The most common clinical manifestations of the ADE were the damage of skin and adnexa,accounting for 51.45%(160 cases),all recovered after receiving corrsponding treatment.CONCLUSION: Allergic history of patients and their family members should be inquired in detail before the use of drugs and high alert should be given to pharmaceutical incompatibility,and the patients should be given fully attention after medication to reduce the incidence of ADE.