6.Preservatives in eyedrops: the advantages, the disadvantages and the countermeasure of use
Chinese Journal of Experimental Ophthalmology 2013;32(11):1003-1005
Preservative is added to multidose eyedrops to ensure that the eyedrops do not become heavily contaminated during patient use,if the active component in the eyedrops do not have a potent antimicrobial effect.There is a large body of evidence from experimental and clinical studies showing that the long-term use of eyedrops with preservative may induce ocular surface damage.It is a system engineering to control the microbial contamination of eyedrops and to relieve ocular surface damage of preservatives.It is the responsibility of drug regulatory departments,the duty of the medicine workers,and the innovativeness studys of the scientific researcher.Then,the best benefit is acquired by the extensive patient with eye disorders.
9.Influence of thymus transplantation on T cell subsets of peripheral blood in patients with allergic rhinitis
Chinese Journal of Organ Transplantation 1998;19(3):177-179
Cultured human embryonal thymus graft was performed on 80 patients with allergic rhinitis to observe the immune function of the patients and the treatment efficiency. The thymus from the fetus of intermediate abortion was cultured for 7 to 10 days. The T cell subsets and serum antigen special IgE(sas IgE) level of the patients were determined before and after the thymus transplantation. The gross treatment efficiency is up to 92.4% among the trial patients after graft for 3 years and CD8 positive cells were increased with a significantly statistical difference (P<0.01), and sas IgE level was much lower than before thymus transplantation (P<0.01). It was concluded that the thymus transplantation might regulate the immune function of the patients with allergic rhinitis, including increases in the number and the function of Ts cells, and a decrease of IgE level.
10.Structural Classification and Functional Characterization ofShort-Chain Scorpion Toxic Peptides
Progress in Biochemistry and Biophysics 2001;28(1):44-48
Recent research has revealed that scorpion venom contains short-chain peptides with the specificity on K+or C1-channels, in addition to the knowledge of many kinds of long-chain peptides with the specificity on Na+ channels. According to the similarity of molecular structure and/or function, they have been classified into several groups. These short-chain scorpion peptides are playing more and more important role in studying the structure and function of K+ or C1- channels. The advance of structure and function of short-chain scorpion peptides in recent years was briefly introduced.