Objective: To observe the stability of tinidaz ole mixed with cefradin in glucose injection under room temperature or 37 ℃ for 8 hours.　Methods:Concentrations of tinidazole and cefrad in were determined by ultraviolet spectrophotometry and pH by a pH meter.　Results: The concentrations of tinidazole and cefradin and the pH of the solution did not change significantly under room temperature and 37 ℃ for 8 hours.　Conclusions: Tinidazole can be mixed with c efradin in glucose injection for clinical use under room temperature or 37 ℃.

Japan’s long-term care insurance takes grassroots governments as its insurer and the elderly and part of the non-elderly as its insured;The costs is shared by government、society和individual, and is, payed through isti-tutions, communities and hothes. Since its establishment, its security level has been increasing, the role of preven-tion has been rising, the status of community-based and home-based has been highlighting, and the cooperation a-mong relevant industry has been strengthening. But at the same time, its costs was soaring during the past decade, and the continued development of the system is facing transformation pressure now. Take this as a warning, the devel-opment of long-term care in China should learn its strong points, but also try to avoid its shortcomings.

An analytical method of reversed phase high performance liquid chromatography (RP-HPLC) was developed for simultaneous determination of 5-hydroxymethylfurfural and nine phenolic compounds (including (+)-catechin, (-)-epicatechin, chlorogenic acid, rutin, caffeic acid, protocatechuic acid, syringic acid, ferulic acid and p-coumaric acid) in 20 min.Ten components were detected and separated successfully by Diamonsil C_(18) column (150 mm x4.6 mm, 5 μm) at wavelength of 280 nm and column temperature of 42 ℃, with acetonitrile and 3% acetic acid solution as the mobile phase in gradient elution.The resultant correlation coefficients of the ten compounds were between 0.9911 and 0.9995 with detection limit from 0.2 to 0.5 mg/L, the RSD less than 2.4% and the average recoveries from 89.4% to 98.3%.These experimental results demonstrate that 5-hydroxymethylfurfural and the nine phenolic compounds in different rice wine samples can be determined with the new method for practical uses.

Objective To explore the influence of behaviour.individuality-personality factors on the intellectual impairment in early period of cerebral infarct.Methods To compare the correlation of the occurence of intellectual impairment and behaviour individuality among 98 cerebral infarct dementia index cases and 80 cerebral infarct without dementia index cases and 87 control subjects.Results A-type behaviour have 63.27％ cerebrol infarct dementia index cases,47.75％ cerebrol infarct without dementia inedx cases,and 35.63％ control subjects.(EPQ)P >60,63.2％ cerebral infarcl domentia index cases,35％ cerebrol infarct without demcntia index cases,and 20.69％ control subjects.(EPO)N>55,42.86％ cerebrol infaret demcntia index cases,38.75％ cerebrol infarct without dementia index cases and 24.14％ control subjects. Conclusion A type behaviour play on important role on intelligence impairment in post cerebral infact.Psychone drviduality and unsteady mood were manly mood feature of cerebral infarct,especially important post cerebral infarct intelligence impairment.

Moyamoya disease is an uncommon chronic progressive occlusive cerebrovascular disease.It is mainly involved in the terminal internal carotid artery and the proximal portions of the anterior cerebral and middle cerebral arteries.Normally,there are differences between the conventional angiographic findings and the clinical manifestations and outcomes in moyamoya disease,while the perfusion imaging can provide important hemodynamic information.Currently,CT perfusion imaging and magnetic resonance perfusion imaging have been widely used in clinical practice.This article reviews the application of the two imaging techniques in moyamoya disease.

Objective To study the effect of applying food composition table and foodstuff substitution method on nutritional status in patients with diabetic nephropathy and undergoing peritoneal dialysis.Methods Forty patients with diabetic nephropathy,treated with peritoneal dialysis for over three months was included in this study.Under the guidance of the food composition table and foodstuff substitution method for six months,nutritional status was compared before and after treatment. Results There was a significant difference in HGS,triceps skin foId thickness(TSF),mid-arm circumference(MAC),midarm muscle circumference(MAMC),Hb,albumin(Alb),serum crcatinine after 6 mortths of intervention compared with those before intervention. Conclusions Food composition table and foodstuff substitution method can obviously impwve the nutritional status for patients with diabetic nephwpathy undergoing peritoneal dialysis and increase the patients'diet compliance as well.

Objective To compare subjective refraction based on power vectors and conventional subjective refraction in different degrees of astigmatism.Methods A total of 143 subjects (143 right eyes) were divided into two groups according to astigmatism degree:low astigmatism group (0-1.50 D) and high astigmatism group (1.50 -3.00 D).Subjects were then examined by both methods to fetch refraction data,and then the equivalent spherical M component,J0 component,J45 component and the duration of refraction procedures were compared and analyzed.Results There was no statistically difference in age,gender,M component,J45 component and time consuming of subjective refraction between the high and low astigmatism groups (all P ＞ 0.05),but intergroup comparison of J0 component from subjective refraction based on power vectors and conventional subjective refraction was significantly different (all P =0.00).In the low astigmatism group,the agreement of M,J0 and J45 measured by the two methods was tmified,and the mean absolute value of M,J0 and J45 difference was 0.04 D,0.02 D and 0.02 D,respectively;moreover,within the limits of consistency,the maximum absolute value of the difference was 0.37 D,0.13 D and 0.17 D,respectively,and there was no statistically difference in time consuming of the two methods (P =0.72).In the high astigmatism group,the agreement of M,J0 and J45 measured by the two methods was poor,and the mean absolute value of M,J0 and J45 difference was 0.43 D,0.21 D and 0.00 D,respectively;moreover,within the limits of consistency,the maximum absolute value of the difference was 0.75 D,0.50 D and 0.30 D,respectively,and the difference in time consuming of the two methods approached statistical significance (P =0.00),suggesting time consuming of subjective refraction based on power vectors was longer.Conclusion Subjective refraction based on power vectors has good effect on low astigmatism,and it needs to be further improved for clinical practices.

In order to improve nursing informationization,and to promote the development of nursing informatics, our nursing department set up a new position called informatics nurse and a series of working systems and man-agement methods were developed. After implementation,the informatics nurse had achieved various goals,including:playing a role in developing 60 nursing information system programs,improving 11 medical and nursing process modification,collecting 399 items of nursing information system problems with 338 items solved,completing 22 nurs-ing information system using instructions,and organizing training meetings and lectures in the hospital for 12 times. The informatics nurse has been appreciated by medical staff and IT engineers who was believed to have promoted the development of nursing informatics in our hospital.

OBJECTIVE:To evaluate the permeation enhancing effect of Flos Caryophylli volatile oil versus azone on diclofenac sodium.METHODS:Percutaneous absorption experiment was performed on the apparatus of isolated skin,and the penetrated amounts of diclofenac sodium at different time were measured,then the steady-state flux and enhancing rate were calculated,and the deposit effect of diclofenac sodium was investigated.RESULTS:Flos Caryophylli volatile oil and azone all had promotion effect on percutaneous absorption of diclofenac sodium,especially when they used in combination.Used either in combination or alone,they all had remarkable enhancement property on deposit effect of diclofenac sodium(P

OBJECTIVE: To analyze the status quo and developing trend of the use of antihyperlipidemics drugs in Chongqing so as to provide information for the research,production,marketing and clinical application of these drugs.METHODS: The consumption sum,DDDs and the defined daily cost(DDC) of Antihyperlipidemics in 18 hospitals in Chongqing city from 2004 to 2006 were analyzed statistically.RESULTS: Both the DDDs and the consumption sum of the antihyperlipidemics showed uptrend over the 3 years,with statins dominating the first place over the 3 consecutive years,making up 48.37%,47.74%,and 61.79% respectively,followed by Chinese patent medicines and fibrates.Xuezhikang and simvastatin ranked among the first two places in terms of DDDs.CONCLUSION: Statins and Chinese patent medicines occupied a predominant role among all the antihyperlipidemic drugs in Chongqing,and their use had a bright prospect.