1.A case of a concomitant rhinophyma and basal cell carcinoma on the nose in a 76-year-old British male
Tetsuya Jumi B. Makino ; Charlene Marie U. Ang-Tiu
Journal of the Philippine Dermatological Society 2024;33(Suppl 1):25-25
Rosacea is a common, chronic condition seen most frequently in lightly pigmented skin presenting with centrofacial redness, papules, pustules, flushing, telangiectasia, and phymatous skin changes. Phymatous rosacea on the nose is called rhinophyma. This condition predominantly affects males in their 5th-7th decade of life. Rosacea has a complex pathophysiology involving the innate and adaptive immune system and its interaction with environmental stimuli. Correlation of non-melanoma skin cancer and rosacea is documented albeit uncommon, and none published from the Philippines.
This is a case of a 76-Year Old British male who presents with a 3 year history of skin colored mass on the nose, which was excised with paramedian forehead flap and was diagnosed with squamous cell carcinoma. In the interim, the patient noted the appearance of rubbery erythematous plaque on the nose with progressively increasing size and erythema and ulceration. Skin punch biopsies were done revealing both infiltrative basal cell carcinoma and rhinophyma. Patient was eventually seen by general surgery and underwent a wide excision.
This case highlights the importance of having a high index of suspicion for malignancies in the appropriate population. The different findings of biopsy sites also reminds us of choosing the appropriate biopsy sites for accurate and timely diagnosis. Lastly, a multidisciplinary approach for successful and comprehensive treatment is of paramount importance.
Human ; Male ; Aged: 65-79 Yrs Old ; Carcinoma, Basal Cell ; Rhinophyma ; Rosacea
2.A case of Nevus Lipomatosus Superficialis in a 14-year-old Filipino female
Ana Aurelia M. Santos ; Karen M. Prieto ; Charlene U. Ang-Tiu ; Milali T. Torres
Journal of the Philippine Medical Association 2017;95(2):66-69
Introduction:
Nevus lipomatosus superficialis is a rare benign hamartomatous skin lesion. It is classified into 2 types: solitary and multiple. Lesions consist of multiple, flesh-colored or yellow papules and/or nodules in a segmental pattern, with a linear, zosteriform, or along the lines of skin folds distribution. Surfaces are smooth, but may also have verrucous or cerebri-form appearance. Pathogenesis is unknown, but there is speculation that precursor cells around dermal blood vessels give rise to mature fat cells in a mosaic pattern. Incidence is presently unknown, but this is the first reported case in this institution. Histopathology reveals presence of aggregates of mature adipose tissue among the collagen bundles of the dermis.
Case Summary:
DF is a 14-year-old, Filipino, female, who consulted due to multiple, pedun-culated, soft papules over the right lower back, and extending to the right flank, with a clustered arrangement. There was no history of trauma or manipulation, nor was there pain, pruri-tus, or other associated symptoms. Past medical, family, and social history were non-contributory. Initial impression was acrochordon. Excision biopsy revealed mature adipose tissue in the dermis, which is diagnostic for nevus lipomatosus superficialis. Serial excision was done.
Conclusion
Excision is the treatment of choice. Other treatment options that can be ex-ploredare COz laser, cryotherapy, and intralesional injection of phosphatidylcholine, which yield promising results recommended by other studies. Dermatopathology plays a vital role in the diagnosis of this condition. A high index of suspicion, a good clinical eye, and dermatopa-thologic analysis are essential tools in clinching the diagnosis.
Nevus
;
Adipose Tissue
3.Angiosarcoma of the scalp in a 79-year-old male: A case report
Erika Kim R. Chan ; Charlene Marie U. Ang-Tiu ; Mary Elizabeth S. Danga ; Michael Jeff B. Fontano
Journal of the Philippine Dermatological Society 2021;30(1):49-52
Introduction:
Angiosarcoma is a rare head and neck sarcoma of vascular endothelial cell origin. We report a case of angiosar-
coma in an elderly male, and the multidisciplinary approach employed in his treatment.
Case report:
A 79-year-old male presented with a 4-month history of a rapidly enlarging black, soft, immovable tumor surround-
ed by bruise-like patches over the right temporoparietal scalp. There was associated pruritus and bleeding when scratched.
Dermoscopy showed bluish black crusts over the tumor, and surrounding violaceous patches. Wedge biopsy revealed a dermis
with irregular vascular spaces infiltrating dermis, lined by atypical endothelial cells. Immunohistochemistry of the atypical in-
filtrative cells was positive for CD31. These findings were consistent with angiosarcoma. The patient underwent wide excision
with a rotational flap and split thickness skin graft. Postoperatively, the patient was referred to Oncology for adjuvant radiation
therapy.
Conclusion
Even with treatment, the prognosis of angiosarcoma remains poor due to its aggressive nature, with a 5-year sur-
vival rate ranging from 10-54%. However, early detection of the disease may increase patient survival rates. This rare case shows
the importance of maintaining a high level of suspicion for lesions that have an atypical presentation to prevent delays in man-
agement and improve patient outcomes.
Hemangiosarcoma
;
Scalp
;
Neoplasms
4.Comparison of the surgical outcomes of minimal incision and elliptical excision in treating epidermal inclusion cysts: A single-center, randomized controlled trial.
John Michael A. RAMOS ; Tetsuya Jumi B. MAKINO ; Charlene Marie U. ANG-TIU ; Maria Franchesca QUINIO-CALAYAG
Journal of the Philippine Medical Association 2025;103(2):64-78
INTRODUCTION
Epidermal inclusion cysts require surgical intervention to prevent recurrence and symptoms. Elliptical excision is definitive but results in longer scar, while minimal incision techniques offer better cosmetic outcomes despite higher recurrence rates probably due to incomplete excision. To date, there are currently no local studies published.
METHODOLOGYA randomized controlled trial was conducted from October 2023 to May 2024 at a dermatology center in the Philippines. Patients were randomly assigned to minimal incision or elliptical excision techniques. Key metrics included operation time, scar length, post-operative complications, Hollander wound evaluation score (HWES), and histopathological completeness of excision.
RESULTSMedian operation duration was 31.86 minutes, with no significant difference between techniques (p = 0.5795). Post-operative scars were longer in the excision group (mean: 2.38 ± 0.66 cm) versus the minimal incision group (p < 0.001). Completeness of excision was higher in the excision group (83%) compared to the minimal incision group (27%) (p = 0.0123). Follow-up scar length was shorter in the minimal incision group (mean: 0.44 ± 0.21 cm) versus the excision group (mean: 2.1 ± 0.63 cm) (p < 0.001). HWES scores showed no significant difference in wound healing and aesthetic satisfaction.
CONCLUSIONMinimal incision technique results in shorter scars but lower completeness of excision compared to elliptical excision. Both techniques have similar long-term outcomes in wound healing and aesthetic satisfaction, with no recurrences or complications beyond two weeks. The choice should balance scar length and completeness of cyst removal, considering patient-specific factors.
Human ; Cicatrix ; Cysts ; Cosmetics