1.Incidence of osteonecrosis of the femoral head in divers: an epidemiologic analysis in Dalian
Dewei ZHAO ; Lei YANG ; Fengde TIAN ; Benjie WANG ; Daping CUI ; Lin GUO ; Nan WANG ; Ying WANG ; Baoyi LIU ; Ning AN ; Weimin FU ; Shibo HUANG ; Wenqiang GU ; Hui XIE ; Chaoqiang WANG ; Wenfeng LUO ; Feiri HUANG ; Kai KANG ; Pengfei LIU
Chinese Journal of Orthopaedics 2012;32(6):521-525
Objective To investigate the incidence of osteonecrosis of the femoral head (ONFH) in divers of Dalian.Methods From January 2010 to December 2010,all registered 855 divers in Dalian were enrolled in this study.All divers underwent a unified medical examination and a questionnaire including height,weight,blood pressure and hip inspection.Radiological examination (anteroposterior and frog position)was used for all divers.Suspicious persons with hip pain but normal X-ray performance were confirmed by MRI.Results Sixty-eight divers were confirmed as ONFH,and the incidence of ONFH in divers of Dalian was 7.95%.According to the Ficat classification,12 patients (12 hips) were in Phase 1,40 patients (47 hips)in phase Ⅱ,3 patients (3 hips) in phase Ⅲ,13 patients (15 hips) in phase Ⅳ.The mean age of divers was 32.6+5.5 years (range,18-55 years).The onset ages of most patients ranged from 30 years to 50 years,accounted for 83.82% (57/68).Among all patients,primary school education accounted for 10.58% (38/359),junior high school education 6.28% (28/446),high school education 4.26% (2/47),university education 0 (0/3); seniority less than 5 years accounted for 4.55% (20/440),6-10 years 9.69% (28/289),11-15 years 13.04% (12/92),16-20 years 21.05% (4/19),more than 20 years 26.67% (4/15); self-employed accounted for 11.88% (19/160),private enterprise 8.41% (38/452),and national enterprise 4.53% (11/243).Conclusion The incidence of ONFH is high in divers of Dalian,which is different in terms of age,seniority,level of education,enterprise nature.
2.Application and development of shape memory polymers in endovascular therapy
Yanyi ZHOU ; Zhaolong LI ; Yaoming ZHANG ; Wenyang HE ; Ruisheng QU ; Chaoqiang CUI ; Dong ZHOU
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2020;27(11):1362-1366
As one of the stimulus-response polymeric intelligent materials, shape memory polymers have been widely applied in biomedicine due to their better biocompatibility, higher controllability, stronger deformation restorability and biodegradability compared with shape memory alloys and shape memory ceramics. This review will introduce the structural principles of shape memory polymers and summarize their applications in the treatment of vascular diseases, especially in endovascular therapy. At the same time, the related technical problems and the future of shape memory polymers are prospected. With the continuous development of processing technology and materials, it can be predicted that shape memory polymers will be more widely used in the medical field.
3.State-of-the-art and outlook of drug-eluting stents
Wenyang HE ; Yanyi ZHOU ; Yaoming ZHANG ; Hao GU ; Ruisheng QU ; Chaoqiang CUI ; Dong ZHOU
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2022;29(07):930-934
Implantation of drug-eluting stents (DES) is one of the most effective treatment for intraluminal vascular diseases such as vascular stenosis caused by atherosclerosis. Antiproliferative drugs offered by could significantly reduce the restenosis of blood vessels, which is beneficial to interventional therapy in more advanced and complex vascular diseases. This review sumarizes the state-of-the-art of the DES based on the function of loaded drug and material of the stents. We hope this review can provide basic information of DES for clinicians and researchers to make more rational choices in practical applications. Moreover, this review also propses the prospects of drug-loaded stents.