ObjectiveTo evaluate selectave blocking of hepatic artery tor hepatectomy in onder to reduce blood loss. MethodsPatients with liver cancer in right hepatic lobe were randomly divided into study group (n =25 ) and control group (n =31).Conventional posterior approach for liver tumor resection was applied.In study group,right hepatic artery was first freed and inflow was temporarily blocked before the right liver lobe was freed from its peripheral attachment.Then hepatectomy was performed under Pringle's manouver. Result in term of blood loss was compared with that in control group in which hepatectomy was performed under Pringle's. ResultsThere were no significant differences between two groups in age,sex,tumor size,liver cirrhosis,HBsAg,AFP and tumor emboli in portal vein.Blood loss in study group was significantty less (272 ± 113 ) ml than that in control group (547 ± 221) ml,the difference was statistically significant(t =-5.6,P ＜ 0.01).The length of hospital stay was significantly shorter than that in control group ( t =- 2.12,P ＜ 0.05 ). ConclusionsInitial hepatic artery blochade before liver freeing during the process of hepatectomy significantly reduced intraoperative in blood loss liver cancer patients.