1.Effect of rocuronium on entropy to endotracheal intubation during propofol anesthesia induction
Xiuying WANG ; Kechang HUANG ; Changxue HUANG ; Cui HE ; Jianhua LI
Chinese Journal of Postgraduates of Medicine 2009;32(15):14-16
Objective To evaluate the effect of rocuronium on entropy to endotracheal intubation during anesthesia induction with propofol. Methods Forty patients anesthetized induction with propofol using a target-controlled infusion were randomly divided into two groups: rocuronium group (R group, 20 cases) received 0.6 mg/kg rocuronium or saline group (S group, 20 cases) received saline. 2-3 min later, endotracheal intubation was performed. Response entropy(RE) and state entropy(SE) were recorded during baseline(Ta), at steady state(Tb), 2 min after rocuro nium or saline administration (Tc) and 0, 1, 2 and 3 min after endotracheal intubation (T0, T1, T2, T3). Results At T2, the RE-SE was higher in S group than that in R group. Endotracheal intubation induced increasing in RE and SE. Comparing T2 and T0 values in R group and S group, SE increased from 42 ± 7 to 50 ± 8 and 43 ± 13 to 55 ± 12, and RE increased from 45 ± 6 to 54 ± 9 and 48 ± 16 to 66 ± 15, respectively. At T0, RE and RE-SE were higher in S group. Conclusion Rocuronium affects RE-SE and RE and RE-SE responses to endotracheal intubation and may confound interpretation of entropy monitoring.
2.Protective effect of exogenous H2 S on oxygen-glucose deprivation and reoxygenation-induced cell injury of SH-SY5Y cells
Changxue WU ; Yanjun DONG ; Yun HUANG ; Zhiyu XIAO ; Yi LI ; Xiaolan QI ; Zhizhong GUAN ; Yan XIAO
Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(5):659-665
【Objective】 To explore the protective effects of exogenous hydrogen sulfide (H