1.ANTI -MUTATION EFFECT OF FLESH OF CLAM MERETRIX MERETRIX LINNAEUS
Zhiling YU ; Changgui DOU ; Wenjun JIANG ;
Chinese Journal of Marine Drugs 1994;0(02):-
The anti-mutation effect of flesh of clam Merectix meretrix Linnaeus was studied . The increase in the rate of micronuclei of mice bone -marrow polychromatic erythrocytes induced by Cy (25 mg/kg X 2d, ip) or Ur (0. 5 g/kg X 4d , ip) was inhibited by decoctio of flesh of Meretrix merelrix Linnaeus (20g/kgX7d, ig).
2.THE PROTECTIVE ACTION OF HYDROLYSATE OF ARCA SUB-CRENATA ON LIVER INJURIES IN MICE
Changgui DOU ; Yongqing YAN ; Zheng ZHANG ;
Chinese Journal of Marine Drugs 1994;0(03):-
Hydrolysate of Area subcrenata (HA) was found to be effective in lowering the elevated SGPT level induced by carbon tetrachloride, thioacetamide (TAA) and pred-nisolone. In addition, HA was shown to shorten sodium pentobarbital sleeping time in both normal and carbon tetrachloride intoxicated mice. The results indicated that HA possessesa significantl protective action on liver injuries in mice.
3.Optimum extraction process of mussel polysaccharide
Hong SHEN ; Yunru PENG ; Changgui DOU
Chinese Traditional Patent Medicine 2006;28(5):746-748
AIM: To: optimize the extraction process of mussel polysaccharide, and then gain higher content of polysaccharide. METHODS: Involved in the three factors, temperature and times of extraction, concentration of NaOH solutions, to do the experiment by orthogonal design uniform design and the method of anthrone. RESULTS: The result showed that the most important factors were temperature of extraction and concentration of NaOH solutions. The optimum extraction conditions were A1B2C1, 4 ℃, 5% NaOH solutions and extracting only once. CONCLUSION: This optimized process is economical, simple, stable and efficient.