1.Optimum extraction process of mussel polysaccharide
Hong SHEN ; Yunru PENG ; Changgui DOU
Chinese Traditional Patent Medicine 2006;28(5):746-748
AIM: To: optimize the extraction process of mussel polysaccharide, and then gain higher content of polysaccharide. METHODS: Involved in the three factors, temperature and times of extraction, concentration of NaOH solutions, to do the experiment by orthogonal design uniform design and the method of anthrone. RESULTS: The result showed that the most important factors were temperature of extraction and concentration of NaOH solutions. The optimum extraction conditions were A1B2C1, 4 ℃, 5% NaOH solutions and extracting only once. CONCLUSION: This optimized process is economical, simple, stable and efficient.
2.ANTI -MUTATION EFFECT OF FLESH OF CLAM MERETRIX MERETRIX LINNAEUS
Zhiling YU ; Changgui DOU ; Wenjun JIANG ;
Chinese Journal of Marine Drugs 1994;0(02):-
The anti-mutation effect of flesh of clam Merectix meretrix Linnaeus was studied . The increase in the rate of micronuclei of mice bone -marrow polychromatic erythrocytes induced by Cy (25 mg/kg X 2d, ip) or Ur (0. 5 g/kg X 4d , ip) was inhibited by decoctio of flesh of Meretrix merelrix Linnaeus (20g/kgX7d, ig).
3.THE PROTECTIVE ACTION OF HYDROLYSATE OF ARCA SUB-CRENATA ON LIVER INJURIES IN MICE
Changgui DOU ; Yongqing YAN ; Zheng ZHANG ;
Chinese Journal of Marine Drugs 1994;0(03):-
Hydrolysate of Area subcrenata (HA) was found to be effective in lowering the elevated SGPT level induced by carbon tetrachloride, thioacetamide (TAA) and pred-nisolone. In addition, HA was shown to shorten sodium pentobarbital sleeping time in both normal and carbon tetrachloride intoxicated mice. The results indicated that HA possessesa significantl protective action on liver injuries in mice.