1.Non-open operation approach for the treatment of bening prostatic hyperplasia (BPH) complicated with Big Bladder Stones.
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To evaluate the mini-invasion approach for the treatment of BPH complicated with big bladder stones. Methods The clinical data of 30 cases of BPH complicated with big bladder stones treated by ESWL,mechanical lithotripsy using the visual lithotriptoscope and TURP or TUVP were retrospectively reviewed. Results 29 cases of big bladder stones were cleared up completely,and all of them were operated on successfully by TURP of TUVP.The operation time was short with minimal invasion The results were satisfactory.No severe complications and bladder stones have recurred up to now. Conclusions ESWL combined with mechanical lithotropsy using the visual lithotroptoscopy and TURP or TUVP is an effective.and non-open operation approach with mini-invasion for the treatment of BPH with big bladder stones.It applys to old patients with cardiovascular and pulmonary conditions,which would elevate the risk of operation.Proficiency in the technique is a key to a successful operation.
2.Research on the Influences of the Implementing Essential Medicine System on Compensation Mechanism of Primary Medical Institutions:analysis on system dynamics
Lülin ZHOU ; Feng JIN ; Changchun ZHAN
Chinese Health Economics 2013;(10):21-23
Objective: To analyze the influences of implementing essential medicine system on primary medical institutions and give suggestions. Methods: Using system dynamics method to construct the compensation mechanism model for primary medical institutions. Compare the growth in revenue and expenditure of primary medical institutions before and after essential medicine system implementation. Results: After the implement of essential medicine system, the growth in total expenditure and total income of primary medical institutions is steadier; when the annual growth rate of government financial subsidies invested more than 13%, the growth in total receipts will keep balance. Conclusion: It’s better to guarantee the government financial subsidies invested in time, raise medical service price properly and establish comprehensive compensation mechanism for implementing compensation mechanism of primary medical institutions.
3.Effects of the Increasing-Energy and Renewing-Wisdom granule on charting-assessed vitality of vascular dementia patients
Jianying ZHOU ; Changchun SUN ; Yuexin GU
Journal of Medical Postgraduates 2003;0(05):-
Objective:To observe the effects of the Increasing-Energy and Renewing-Wisdom granule on vascular dementia(VD) patients. Methods:42 VD patients were divided randomly into 2 groups. The patients in treatment group administered the Iincreasing-Energy and Renewing-Wisdom granule. The patients in control group administered piracetam. All the patients were treated for 3 months. Results: The patients' scores of HDS, MMSE, Wechsler (order), MQ in the treatment group were higher than those before the study (P
4.Effect of Xiao Jianzhongtang on AMPK/PGC1-α Signal Pathway in Skeletal Muscle of Exercise Fatigue Mice
Zhi-hui LIN ; Qing-ying ZHOU ; Meng-ni WANG ; Bing LING ; Pai LIU ; Jun-peng GUO ; Hong-yan LIU
Chinese Journal of Experimental Traditional Medical Formulae 2020;26(13):73-78
Objective:To observe the effect of Xiao Jianzhongtang on Adenylate-activated protein kinase/peroxidase proliferation-activated receptor coactivator 1-
5.Research progress on Parkinson disease pain classification and treatment plans
Journal of Apoplexy and Nervous Diseases 2023;40(12):1149-1152
Parkinson disease is a common neurodegenerative disease characterized by motor and non-motor symptoms, and pain is one of the typical non-motor symptoms that has considerable negative impact on the daily life of patients with Parkinson disease, which has been a clinical focus. For the various types of pain in Parkinson disease, the treatment options are different, and early pain identification and early reasonable and effective treatment can delay the progression of the disease. This study presents the Parkinson disease pain classification and treatment plans, aiming to provide a basis for clinical diagnosis and treatment.
6.Effect of Intensive Insulin Therapy on Inflammatory Level of Biliary Pyemia
Changchun PU ; Xigui ZHOU ; Jieliang HU ; Faping LI
Chinese Journal of Bases and Clinics in General Surgery 2008;0(12):-
Objective To explore the possible anti-inflammatory mechanism of intensive insulin therapy (IIT) by studying the effect of IIT on the levels of TNF-?,IL-6,C-reactive protein (CRP) and APACHE Ⅱ score in biliary pyemia.Methods Twenty eight patients with biliary pyemia who were admitted by our department and given an operation within 24 h form Jan.2005 to Dec.2008 were randomly divided into two groups by using random number table numbers:one group treated with IIT (IIT group,n=14) and another group treated with routine insulin therapy (RIT group,n=14).The inflammatory factors,such as TNF-?,IL-6 and CRP were detected dynamically and the APACHEⅡ score was calculated.Results The level of CRP and APACHEⅡ score on day 5 and 7 and the levels of TNF-? and IL-6 on day 3,5 and 7 after operation in IIT group were significantly lower than those in RIT group (P
7.To observe the treatment effect of nicardipine for the presence of hypertension responses at during thyroidectomy under cervical plexus nerve block
Zhou ZHANG ; Guoming HAO ; Changchun ZHANG ; Liangjie ZHENG
Chinese Journal of Primary Medicine and Pharmacy 2005;0(02):-
Objective To observe the treatment effect of nicardipine for the presence of hypertension responses during thyroidectomy under cervical plexus nerve block.Methods Patient without hypertension before the operation was brought into if he received thyroidectomy under cervical plexus nerve block,and with the presence of hypertension responses during the operation,and without effect after injected innovar one dose or dolantin 50mg by vein when the blood pressure was over 160/90mmHg.20 patients according to the criterion mention above were dripped nicardipine 20?g/kg by vein.The SBP,DBP,MAP,HR,SpO_2 and ECG were recorded at 3min,5min,15min,30min,45min after injection and the side effects were also recorded.Results The SBP,DBP,MAP of all patients were fallen distinctly at 3min after injection,and reached lowest at 5min.The blood pressures were steady at other points.There was significantly difference between the point before and after injection(P
8.Observation on therapeutic effect of tramadol combined with fentanyl in patient controlled intravenous analgesia after nucleotomy of intervertebral disc
Liwen QIN ; Liangjie ZHENG ; Guoming HAO ; Zhou ZHANG ; Changchun ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2006;0(07):-
Objective To observe the therapeutic effect of tramadol combined with fentanyl in patient controlled intravenous analgesia after nucleotomy of intervertebral disc.Methods 60 patients under general anesthesia,scheduled for nucleotomy of intervertebral disc,were randomly divided into three group(n=20):group tramadol(group T),group fentanyl(group F) and group tramadol+fentanyl(group TF).All patients were received patient controlled intravenous analgesia by loading dose+background dose+PCA bolus dose.The BP,HR,RR,VAS at 6,12,24,48h of postoperation were observed.The sedation score in 24h,average effective-press times and drug dose in 48h of postoperation were recorded.The incidence of nausea and vomiting during 24h of postoperation were observed.Results It had no significantly difference of BP,HR,RR,VAS among three groups.The average effective-press times of group TF (8?2) were significantly less than those of group T (14?3) and group F (12?3).The drug dose of 48h was tramadol (17.9?1.5)mg/kg(group T),fentanyl (16.8?1.5)?g/kg(group F) and tramadol (11.5?0.7)mg/kg+fentanyl (9.1?0.7)?g/kg(group TF).The drug dose of group TF showed significant difference compared with others.The sedation score in group F was the highest,it had significant difference compared with the other two group.The frequency of nausea and vomiting in group T was significantly more than that in others.Conclusion Tramadol or fentanyl gived alone can afford the same satisfied analgesic effect on nucleotomy of intervertebral disc.But there is high nausea-vomiting frequency in tramadol and strong sedation frequency in fentanyl.Tramadol combined with a little opioid fentanyl can afford more satisfying analgesic effect,and is provided with advantage in less drug and side-effect.
9.Mitochondrial DNA Polymorphism Associated with Longevity in Taklimakan Desert Uygur Centenarians
Nijiati MUYESAI ; Changchun QIU ; Zuheng CHENG ; Wenyu ZHOU
Journal of Medical Research 2006;0(06):-
Objective Sequence variations in mitochondrial DNA genes have been found to influence successful aging and longevity. The aim of this study was to examine whether mitochondrial DNA polymorphisms influenced the longevity in Chinese Uygur population.Methods We genotyped the mt5178A and mt10398G in 277 sampels representing three age group (centenarian, n=65; longevity, n=100; controls, n=112) from Taklimakan desert Uygur centenarians,China Results The distribution frequency of the 5178A in the centenarian (51/65, 78.5%) is slightly higher than in those of controls (63/112,56.3%,P=0.0029) . The frequency of the 10398G were significantly higher among the centenarian(47/65,72.3%)and longevity(68/100,68%) in comparison to the controls(60/112,53.6%,P
10.Genetic analysis of ?-ADDUCIN and GNB3 in essential hypertension patient
Hongye ZHAO ; Jun CAO ; Li ZHOU ; Bin WANG ; Changchun QIU
Basic & Clinical Medicine 2006;0(04):-
Objective To explore the polymorphism at position G460W of ?-ADDUCIN and at position C825T of GNB3,and the genetic interaction between ?-ADDUCIN and GNB3 genes in a QiQihr essential hypetension population.Methods Three hundreds and thirty-one patients with EH and two hundreds and ninety-three healthy controls were enrolled.Genotyping was performed using PCR-RFLP technique.Results(1)genotype distributions of ?-ADDUCIN G460W(GG 0.177 vs 0.160,GW 0.580 vs 0.481,WW 0.242 vs 0.359,P=0.006) and GNB3(CC0.177 vs 0.353,CT 0.468 vs 0.541,TT 0.355 vs 0.106,P