1.A study on the adverse effects of extracorporeal shockwave lithotripsy (ESWL) for renal stones
Xikun WANG ; Youzhi WANG ; Yanhui GU ; Changbao XU ; Pengsen WANG
Chinese Journal of Urology 2016;37(8):578-582
Objective To study the reason and the preventive measures that adverse effects of extracorporeal shockwave lithotripsy (ESWL) for renal stones during treatment.Methods From April 2015 to January 2016,165 patients who underwent ESWL treatment for renal stones were enrolled this retrospective study.All patients were in supine position.Direction of shockwave was by the path of preabdomen.The adverse effects during treatment were observed.The related factors were analyzed by Logistic regression analysis.Results There were 70 cases(42.4%) with pain,10 cases(6.1%) with cold sweat,8 cases (4.8%) with accelerated heart rate,5 cases (3.0%)with descent of heart rate,2 cases (1.2%) with nausea and vomiting.In the univariate Logistic regression analysis,four variables (BMI,history of ESWL treatment,stone location and energy) were found showing statistical significance.Multivariate Logistic regression analysis showed that the final significant related factors were BMI < 24.0 kg/m2 (OR =4.155,CI 1.373-12.571),history of ESWL treatment (OR =0.163,CI 0.058-0.454),stone in pelvis(OR =123.051,CI 17.638-858.439),stone in middle calyceal (OR =169.171,CI 29.677-964.343),energy 86.3-94.7J (OR =0.094,CI 0.025-0.362).Conclusions Pain was the most common adverse effect during the treatment of ESWL.Stone location (pelvis and middle calyceal) was an independent risk factor,BMI < 24.0 kg/m2 was one of the related risk factors.Both energy 86.3-94.7J and history of ESWL treatment were preventive factors.
2.Segmental instrumentation plus vertebral augmentation for treatment of Denis type B thoracolumbar burst fracture
Xue WANG ; Xinlong MA ; Xiaolin ZHANG ; Changbao CHEN ; Baoshan XU ; Gongyi LYU ; Tao WANG
Chinese Journal of Trauma 2014;30(9):898-902
Objective To evaluate the effects of posterior segmental pedicle screw instrumentation and augmentation using calcium sulphate cement in treatment of Denis type B thoracolumbar burst fractures.Methods Forty patients with Denis type B thoracolumbar burst fracture treated between January 2011 and December 2012 were reviewed retrospectively.Twenty patients received posterior short-segment pedicle screw fixation in conjunction with screw placement at the level of fracture and calcium sulphate augmentation without posterolateral fusion (combined treatment group),but 20 patients underwent traditional short-segment pedicle screw fixation (conventional treatment group).Radiographs and CT scans evaluated local kyphotic angle on the spot of injury,anterior height of the injured vertebra,and canal encroachment before and after operation and at final follow-up.Meanwhile,visual analogue score (VAS),Oswestry disability index (ODI),and neurologic status based upon ASIA 2000 were assessed.Results Mean follow-up period was 15 months (range,12-24 months).Vertebral height restoration was equivalent of the two groups immediately after operation,but better result of kyphosis correction was found in treatment group than in control group (P < 0.05).Anterior vertebral height and kyphotic angle significantly improved in treatment group compared to control group at final follow-up (P < 0.05).Clinical and neurologic outcome evaluation were similar between the two groups.No implant failure occurred at follow-up.Conclusion For Denis type B thoracolumbar burst fractures,posterior segmental pedicle screw fixation augmented with calcium sulphate is effective for reducing correction loss and implant failure,compensating for the deficiencies of conventional fixation.
3."Clinical research on flexible ureteroscope ""one step"" treat impacted upper ureteric calculi"
Yuan LYU ; Changbao XU ; Jing MA ; Xinghua ZHAO ; Xiaofu WANG ; Wuxue LI
Chinese Journal of Urology 2017;38(5):371-374
Objective To evaluate the effect of one step flexible ureteroscopic lithotripsy for incarcerated upper ureteral calculi.Methods The clinical data of 80 cases of incarcerated upper ureteral calculi were retrospectively analyzed between August 2015 and September 2016.Theone step flexible ureteroscopic lithotripsy was used in 40 cases (one step group),including 22 male cases and 18 female cases.The average age was (40.0 ± 9.5) years.The maximal stone diameter was (i.8 ± 0.5) cm.The widest width of the ureter above the stone was (2.5 ± 1.1) cm.The CT value of stone was (1 089.0 ± 111.3) HU.Two step method was used in 40 cases (two step group),including 21 male cases and 19 female cases.The average age was (41.0 ± 10.7).The maximal stone diameter was (1.7 ± 0.6)cm.The widest width of the ureter above the stone was (2.3 ± 0.9) cm.The CT value of stone was (1 002.0 ± 97.2) HU.During the one step flexible ureteroscopic lithotripsy,only flexible ureteroscope was used to crush the stone,no matter whether the stone located in the ureter or return to the renal pelvis.During two stepmethod,the rigid ureteroscopy was firstly used for crushing the stone in the ureter.When the stone return to the renal pelvis,the rigid ureteroscopy was change into flexible ureteroscope for continuous crushing the stone.Compared two groups' operating time,2 weeks stone clearance rate and the cases of fever after operation.Results The mean operative time in the one step group was (37.45 ± 11.34) min.The mean operative time in the two step group was (55.07 ± 13.57) min.The difference was statistically significant (P < 0.05).The number of infection 2 cases in one step group and 9 cases in two step group.The difference was statistically significant (P < 0.05).2 weeks stone clearance rate was 87.5% (35/40) in one step group and 82.5% (33/40)in two step group.There was no significant difference between two groups.Conclusions Flexible ureteroscope one step method is a safe and effective alternation for incarcerated upper ureteral calculi.
4.Clinical diagnosis and treatment of severe hydronephrosis induced vagus reflex by percutaneous renal puncture decompression
Wuxue LI ; Changbao XU ; Xinghua ZHAO ; Bin HAO ; Youzhi WANG ; Changwei LIU ; Xiaofu WANG
Chinese Journal of Urology 2021;42(3):229-230
Vagus nerve reflex is a rare complication of percutaneous renal decompression. It is often induced by excessively rapid decompression of severe hydronephrosis and traction of the main nerves innervating the kidney. The clinical manifestations are irritability, sweating, clammy skin, hiccups, slow heart rate. It is easy to misdiagnose. In this study, 4 patients with vagus nerve excitement after percutaneous renal decompression were treated. After monitoring the patient’s vital signs and giving treatment such as expanding blood volume and raising blood pressure, the symptoms gradually disappeared.
5.Clinical application of physical vibration lithecbole in upper urinary calculi after extracorporeal shock-wave lithotripsy
Changbao XU ; Youzhi WANG ; Xiaohan CHU ; Bin HAO ; Xinghua ZHAO ; Xiaofu WANG
Chinese Journal of Urology 2013;34(8):599-602
Objective To observe the curative effect of external physical vibration lithecbole (EPVL) therapy after extracorporeal shock-wave lithotripsy (ESWL) in upper urinary calculi.Methods A total of 133 patients of upper urinary calculi with randomly divided into 2 groups after ESWL therapy during the period of 2012 October to 2013 February.The EPVL group (66 cases) used the physical vibration lithecbole treatment,and the natural lithecbole group (67 cases) used the method by drinking water,adding exercise and other natural lithecbole method.Of the EPVL group,6 of the stones were located in the upper or middle calyx,13 in renal pelvis,16 in lower renal calyx and 31 in ureter,the stone diameter was 10-15 mm.Of the natural lithecbole group,8 of the stones were located in the upper or middle calyx,17 in renal pelvis,15 in lower renal calyx and 27 in ureter,the stone diameter was 10-15 mm.The clinical data of the curative effect,side-effect,and complications were collected and analyzed systematically.Results In the EPVL group,the average times of lithagogue treatment was 2.6 times,51 patients (77%) expelled stones on the day of lithecbole,and the stone free rate in a week was 79% (52/66).Especially,81% (13/16) of the lower renal calyx expelled stones on the day of lithecbole,and the stone free rate in a week was 88% (14/16).Whereas,30 patients (45%) in the natural lithecbole group expelled stones on the day of ESWL,and the stone free rate in a week was 49% (33/67) ; the lower renal calyx stone expulsion rate on the day of ESWL was 33% (5/15),and the stone free rate in a week was 40% (6/15).The curative effects were significantly different between the 2 groups (P< 0.05).There were no serious complications in both groups.Conclusions EPVL machine can significantly promote the stone expulsion after ESWL.Compared with traditional methods,EPVL therapy has a better curative effect,especially on lower renal calyx stones.EPVL is a safe and noninvasive treatment.
6.Posterior short-segment instrumentation without fusion for severe thoracolumbar burst fractures
Xiaolin ZHANG ; Xinlong MA ; Changbao CHEN ; Baoshan XU ; Gongyi Lü ; Xue WANG ; Hongfeng JIANG
Chinese Journal of Trauma 2013;(6):493-497
Objective To evaluate the clinical efficacy of treatment of severe thoracolumbar burst fractures by posterior short-segment instrumentation without spinal fusion and assess radiographic imaging and function recovery after surgery.Methods Thirty-eight patients with severe monosegmental thoracolumbar burst fractures treated between July 2011 and March 2013 were analyzed retrospectively.Operation procedures were posterior short-segment pedicle screw distraction reduction and fixation combined with screw insertion to the injured vertebrae and calcium sulphate augmentation.In addition,there was no need for posterolateral interbody fusion.X-ray and CT were performed before and after operation to evaluate local kyphotic angle,anterior fractured vertebral body height and canal encroachment.Visual analogue scale (VAS) and Oswestry disability index (ODI) were assessed before and after operation as well as in follow-up.Results All patients were followed up for average 14 months (range,3-20 months).Local kyphotic angle was (21.2 ±4.3)° before operation,(3.5 ± 1.8)°immediately after operation,and (4.8 ± 2.7) ° in final follow-up.Relative anterior vertebral height was (54.8 ± 14.6)% before operation,(91.7 ± 8.0)% after operation,and (87.2 ± 6.0)% in final follow-up.Mean canal encroachment was (48.0 ± 4.5)% preoperatively,(23.8 ± 7.8)%postoperatively,and (8.8 ± 4.6) % in final follow-up.In final follow-up,six patients with American Spinal Injury Association (ASIA) grade C on admission showed improvement to grade D (n =2) and grade E (n =4) ; 10 patients with ASIA grade E on admission showed improvement to grade E; 22 patients with grade E had no changes.ODI and VAS scored 15.5 ±8.8 and 2.3 ±0.8 in final follow-up with substantial improvement from those before operation (P < 0.01).Complications from internal fixation were not found during follow-up.Conclusion Posterior short-segment fixation without fusion is one of the foremost effective methods for severe thoracolumbar burst fractures,for it can effectively restore the sagittal spinal alignment and the fractured vertebral body height.
7.Determination of the composition of kidney stones and prediction of the efficacy of extracorporeal shock-wave lithotripsy by X-rays
Changbao XU ; Bin HAO ; Youzhi WANG ; Xinghua ZHAO ; Liang YAN ; Xiaohan CHU ; Yuan LV
Chinese Journal of Urology 2012;33(1):13-15
Objective To evaluate the clinical value of determination of composition of kidney stones by shap and density and of prediction of the efficacy of extracorporeal shock-wave lithotripsy (ESWL) by X-rays. Methods The data of 358 patients were analyzed,with 204 male and 154 female and with 276 cases of solitary stones and 82 cases of multiple stones.Determine the composition of kidney stones by shap and density,predict the efficacy of ESWL by X-rays,and choose the appropriate method of treatment.Analyze stone chemical property by Infrared stone composition automatic analyzer to checkout the prediction results before surgeries. Results 339 cases were successful to remove stones after treatment.The prediction results of 308 cases (86.0%) were consistent in stone chemical property,and the preperative prediction results of 339 cases (94.7%) were consistent in ESWL efficacy. Conclusions Determination of composition of kidney stones and prediction of the efficacy of ESWL by X-rays were feasible.
8.Clinical observation of the double-J stent indwelling time in the treatment of ureteral complicated calculi post-ureteroscope
Wuxue LI ; Xinghua ZHAO ; Changbao XU ; Youzhi WANG ; Yuan LV ; Junjie LU
The Journal of Practical Medicine 2017;33(2):256-258
Objective To systematically evaluate the optimal indwelling time of double?J stent in the treatment of ureteral complicated calculi post?ureteroscopy. Methods A total of 161 patients with complicated ureteral calculi were enrolled in this study from August 2012 to August 2015. All patients received the treatment of ureteroscopic holmium YAG Laser lithotripsy and were randomly divided into 3 groups according to varied double?J stent indwelling time: group A < 2 weeks (n = 43),group B from 2 ~ 6 weeks(n = 67),and group C>6 weeks (n = 51). Complications of three groups were compared and the hydronephrosis after removing double?J stent was recorded. Results The rate of complications of group C was significantly higher than that in group A and group B (P<0.017). However,group A(10/43)has a higher rate of ureterostenosis after removing double?J stent compared with group B(4/67)and group C(3/51),while no statistical significance was observed between group B and group C. Conclusion The incidence of complications after lithotripsy increased with the indwelling time of double?J stent,but the short indwelling time would led to ureterostenosis. Therefore,the optimal indwelling time of double?J stent after flexible ureteroscopy was 2 to 6 weeks,and the indwelling time for patients with injury ureteral mucosa could be appropriately prolonged.
9.The prognostic evaluation of arterial blood lactate and lactate clearance rate in patients with craniocerebral trauma
Jing HUANG ; Changbao HUANG ; Zhaorui SUN ; Ji XIE ; Zhizhou YANG ; Danbing SHAO ; Yang XU ; Hongmei LIU ; Shinan NIE
Journal of Medical Postgraduates 2016;29(9):933-936
Objective After acute craniocerebral trauma , to a certain extent , arterial blood lactate and lactate clearance rate reflect the illness severity .We aimed to investigate the prognosis value of arterial blood lactate and lactate clearance rate in patients with craniocerebral trauma . Methods 94 cases with craniocerebral trauma treated in the Department of Emergency of Nanjing General Hospital of Nanjing Military Regionfrom February 2015 to November 2015 were retrospecively analysed .GCS ( Glasgow Coma Scale ) score, arterial blood lactate , blood pressureand heart rate were measured once patients admitted to hospital and 6 hours later ,arterial blood lactate was measured again to calculated the arterial blood lac-tate clearance rate .Based on the GCS score , we divided the patients into mild group (13-15), medium group (9-12) and severe group (3-8).We also divided the patients into death group and survival group according toprognosis .We compared arterial blood lactate and lactate clearance rate betweeeneach group respectively . Results There were significant differences in arterial blood lactate (F=19.99,P<0.01) and 6h lactate clearance rate(F=6.21,P<0.01)be-tween lighter group , medium group and severe group .The initial arterial blood lactate of death group was significantly higher than sur-vival group[(4.20 ±1.36)mmol/L vs (1.58 ±0.93)mmol/L], the difference was statistically significant (t=-9.78,P<0.01). The 6 h lactate clearance rate of death group was significantly lower than survival group [(31.73 ±12.84)%vs (46.25 ±12.01)%], the difference was statistically significant (t=4.55,P<0.01). Conclusion Arterial blood lactate and 6 h lactate clearance rate can evaluate the severity and prognosisof illnessin patients with craniocerebral traumaand have important application value in clinical work .
10.Allergic fungal rhinosinusitis: one case and literature review.
Geng ZHANG ; Changbao NI ; Yi XU ; Huifang ZHOU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;24(11):496-501
OBJECTIVE:
To investigate the presentation and the management of allergic fungal rhinosinusitis (AFRS).
METHOD:
One case of AFRS was reported and the relevant literatures were reviewed. CT scan showed high-attenuation like "cloud and mist", Charcot-Leyden crystals and fungal hyphae were found in nasal smear.
RESULT:
The patient removed after a combined therapy of endoscopic sinus surgery, steroids and local antifungal drugs.
CONCLUSION
The diagnosis of AFRS depends on history, the characteristics of CT scanning, pathology, mycologic and immunologic test. The management of surgery, systemic immunotherapy, local antifungal drugs and longer follow up is very important.
Fungi
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isolation & purification
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pathogenicity
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Humans
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Male
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Mycoses
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diagnosis
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therapy
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Rhinitis, Allergic, Perennial
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diagnosis
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microbiology
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therapy
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Young Adult