1.Imunological characterization of antigens from cysticercus and sparganum and their application to immunodiagnosis 1. Immunological characteristics of crude antigenic components from Cysticercus cellulosae.
The Korean Journal of Parasitology 1988;26(4):245-254
We studied the serological reaction between various antigenic components from Cysticercus cellulosae and IgG antibodies in sera of cysticercosis, sparganosis, hydatidosis patients and normal humans by ELISA and EITB. In serological tests by ELISA, we recognized cross reaction of Cysticercus antigenic components with IgG antibodies in heterologous sera such as sparganosis and hydatidosis patients or normal humans. The crude antigenic components of Cysticercus showed lower ELISA sensitivity in homologous sera from cysticercosis patients than heterologous sera from hydatidosis patients. A total of 31 polypeptide bands with 260 KDa-22 KDa molecular weights were detected by SDS-PAGE, and 11 of them showed strong intensity. Total 22 components of them were recognized by IgG antibodies in cysticercosis patients sera. However, 12 of them were recognized also by normal human sera, 11 were by sparganosis sera, and 21 were by hydatidosis patients sera. The crude antigenic components of 104 KDa, 82 KDa, 72 KDa, 59 KDa and 34 KDa molecular weights were nonspecific ones, which cross-reacted with sera of either cysticercosis, sparganosis, hydatidosis patients or normal humans.
parasitology-helminth-cestoda
;
Spirometra erinacei
;
Taenia solium
;
cysticercus
;
sparganum
;
immunology
;
antigen
2.A Case of Cutaneous Lymphatic Rupture on Calf Secondary to Punch Biopsy.
Korean Journal of Dermatology 2018;56(5):343-344
No abstract available.
Biopsy*
;
Lymphography
;
Rupture*
3.Fatigue Failure of Wire in Orthopaedic Use
In KIM ; Han CHANG ; Kyung Hwan CHOI
The Journal of the Korean Orthopaedic Association 1988;23(5):1350-1356
Orthopaedic wire has been used widely as a good internal fixator in cases of fracture, the ligament reconstruction, and for the stabilization of cervical spine. But if it is used inappropriately, a wire can be easy to fail by elongation, untwisting, or breakage. Among them, the most common failure of wire is breakage. To clarify the mechanism and the causes of wire failure, the authors analysed serial roentgenograms and scanning electronmicroscopic findings of broken wire in total 13 cases, which were experienced at the department of orthopaedic surgery, St. Mary's Hospital, Catholic University Medical College From January 1981 to December 1987. The results obtained were as follows :1. The mechanism of wire failure were classified into the 4 types ; minor continual flexing motion in 6 cases, repeated minor back and forth torsion in 1 case, tension failure in 2 cases and combined type in 4 cass. 2. The causes of wire failure were in appropriate use and inadequte application, a lack of s ufficient mechanical strength, micromotion due to inadequate postoperative imm obilization, early mobilization before tissue healing as well as certain injuries to the wire during handling in operation.
Early Ambulation
;
Fatigue
;
Internal Fixators
;
Ligaments
;
Spine
4.Clinical review of thoracic and lumbar spine fractures.
Myeong Ok KIM ; Chang Hwan KIM ; Sei Joo KIM
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(4):595-603
No abstract available.
Spine*
5.Clinical spectrum of epidermolysis bullosa acquisita.
Chang Woo LEE ; Yung Hwan KIM ; Soo Chan KIM
Korean Journal of Dermatology 1992;30(5):577-584
The clinical spectruni of epidermolysis bullosa acquisita(EBA) is much broader than originally thought. Although the full extent of the clinical presenation is still being defined, it is now known that EBA include the followings: a non-inflammatory mechanobullous condition equating wit,h classical EBA; an inflammatory vesiculosullous eruption mimicking bullous pernphigoid; and a mucosal-centered disease with sarring similar to cicatricial pemphigoid. Among the nine cases of EBA, aged between 34 to 70 year-old, seen in recent years, three patients had mechanobullous lesions with skin fragilities and scarrings; three patients had inflammatory bullous eruptions, and three other patient had combined features of mechanobullous/inflammatory bullous lesions. Mucous membrane lesions were recognized in sex cases, and the rnos! frequent site of involvement was the oral mucosae. According to observations of these patients episodes of inflammatory bullous eruptions appeared to be present in seven cases and have been considered as early sympoms of the disease. It has been noted, however, that in two cases lesions develop d as an non-inflammatory mechanobullous from thonset. Based on the ability of EBA to mimick bullous pemphigoid or cicatricial pernphogoid and the fact that such cases have perhaps been missed, we feel EBA is more common than past literature has suggested.
Aged
;
Blister
;
Cicatrix
;
Epidermolysis Bullosa Acquisita*
;
Epidermolysis Bullosa*
;
Humans
;
Mouth Mucosa
;
Mucous Membrane
;
Pemphigoid, Benign Mucous Membrane
;
Pemphigoid, Bullous
;
Skin
6.Tre atment of Gonorrhoea with Antibiotic Combinations : Kanamycin plus Ampicillin / Probenecid versus Kanamycin plus Talampicillin / Probenecid.
Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1985;23(6):745-751
riie snbjects werc 269 patients with uncomplicated gonococcal urethritis, who visited the Veiereal Disease Clinic of Choong-Ku Public Health Center in Fieoul from August to Decernber 1984. ()ni hundred and four of 108 patients treated with 1.anamycin, 2 gm, IM plus anipi illin,3.5 gm, p0 plus probenecid, 1 gm, PO regirrien recovered with 65(62. 5 post-gonococcal urethritis(PGlJ) and 4(3.7%) failed, One hundred and seven of III patients treated with kanamycin, 2 gm, IM plus talarnpicillin, 2 gm, PO plus probenecid, 1 gm, po regimen recovered with 71 (66. 4% ) post-goriococcal urethritis and 4(3. 6%) failed. It is suggeste,d that both these antibiotic comlbination regimens have similarly good effect in the treatment. of gonococcal urethritis.
Ampicillin*
;
Humans
;
Kanamycin*
;
Probenecid*
;
Public Health
;
Talampicillin*
;
Urethritis
7.Comparative study of immune parameters in advanced gastric cancer and tuberculous pleurisy.
No Kyung KIM ; Dae Suk HUH ; Chang In SEO ; Young Hwan KIM
Journal of the Korean Cancer Association 1993;25(3):315-324
No abstract available.
Stomach Neoplasms*
;
Tuberculosis, Pleural*
8.The Clinical Values of Metaplasia, p 53, c - erbB2 and CEA Expression in Gallbladder Carcinoma.
Seok Mo KIM ; Seong Hwan KIM ; Jeong Hwan CHANG ; Sung chul LIM ; Chae Hong SUH
Journal of the Korean Cancer Association 1999;31(6):1261-1270
PURPOSE: We evaluated the correlation between the carcinogenesis of gallbladder and the expression of lysozyme, p53, c-erbB2 and CEA in gallbladder lesions. MATERIALS AND METHODS: Thirty cases of gallbladder lesions (containing 17 cases of GB carcinoma) were examined. We analyzed the clinicopathologic findings of the early (stage I & II) and advanced carcinoma (stage III, IV & V) and those of carcinoma with or without metaplasia in the tumor. We performed p53, c-erbB2 and CEA immunohistochemical staining and compared their findings with those of normal mucosa and preneoplastic lesions. We also performed lysozyme immunohistochemical staining and compared its finding with metaplastic and non-metaplastic lesions. RESULTS: There are two distinct genetic pathways in gallbladder cacinogenesis and metaplastic carcinoma was more frequent than non-metaplastic carcinoma. Metaplasia of gallbladder did not reveal any difference of the clinicopathologic findings and depth of invasion (Nevin stage). Lysozyme expression was found in all metaplastic lesions but non-expression did not indicate non-metaplastic lesions. p53 mutations and c-erbB2 alterations may have a role in the carcinogenesis of gallbladder carcinomas, especially, in a late event, and in an early and late events, respectively. The correlation of p53 and c-erbB2 expressions was found but which did not indicate that the co-expression was needed in the carcinogenesis. CEA immunohistochemical staining may be helpful in the differential diagnosis of benign lesions and precancerous and cancerous lesions of the gallbladder. CONCLUSION: These results suggest that p53 mutations and c-erbB2 alterations may have a role in the carcinogenesis of gallbladder carcinomas, especially, in a late event, and in an early and late events, respectively.
Carcinogenesis
;
Diagnosis, Differential
;
Gallbladder*
;
Metaplasia*
;
Mucous Membrane
;
Muramidase
9.Cord plasma lipid and lipoprotein levels of newborn infants.
Chang Joo KIM ; Hyoung Moo PARK ; Do Hwan BAE
Korean Journal of Perinatology 1993;4(3):285-294
No abstract available.
Humans
;
Infant, Newborn*
;
Lipoproteins*
;
Plasma*
10.Oral Lichen Planus: Report of A Case.
Hack Chul SHIN ; Chang Woo LEE ; Joong Hwan KIM
Korean Journal of Dermatology 1982;20(3):493-499
Lichen planus is rare in Korea. and oral lichen planus is even rarer. To our knowledge, this is the first case reporting in Korean dermatological literature. 57 year-old man was seen for erythema with white striation on the oral mucosa in December 1981. The initial lisior s appeared on the buccal mucosa of left side of oral cavity 10 months ago. Thereafter he noticed similar lesions on the right side of buccal mucosa, hard palate, left side of upper and lower gingiva and left side of the lower lip. Histopathological and direct immunofluorescence studies showed typical features of lichen planus. Administration of griseofulvin(0.5gm. of Fulvicin' daily) for 4 weeks resulted in no clinical improvement. Oral retinoid(25mg of Ro 10-9359 daily) for 11 weeks resulte3 in healing of lesions with no side effect except slight dryness of the mouth.
Erythema
;
Etretinate
;
Fluorescent Antibody Technique, Direct
;
Gingiva
;
Humans
;
Korea
;
Lichen Planus
;
Lichen Planus, Oral*
;
Lip
;
Middle Aged
;
Mouth
;
Mouth Mucosa
;
Palate, Hard