1.Association of body mass index and outcomes of patients admitted for decompensated heart failure among adult Filipino patients in a tertiary hospital in Cebu City
Darius R. Enario, MD ; Jovy Louie Anthony R. Vergara, MD ; Ceryl Cindy Y. Tan, MD
Philippine Journal of Internal Medicine 2023;61(2):45-51
Introduction:
Obesity remains to be a public health concern across the globe. Studies have established that obesity plays
an important role in the pathogenesis and progression of cardiovascular diseases such as hypertension and coronary artery
disease. Evidence suggesting the link between obesity and decompensation of heart failure is only just emerging.
General Objective:
Determine the associations between body mass index (BMI) outcomes of severity and mortality among
adult Filipino patients admitted with decompensated heart failure.
Study Design:
Retrospective Cohort study design.
Study Setting:
Chong Hua Hospital, a tertiary hospital in Cebu City, Philippines
Study Population:
All adult patients with a diagnosis of Decompensated heart failure who were admitted in the hospital
from 2015 to 2019.
Main Outcome Measure:
Determine association of BMI using Asian cut-offs and Outcomes of patients admitted for
decompensated heart failure.
Results:
A total of 356 patients were admitted for acute decompensated heart failure from year 2015-2019. Majority of the
patients were in the obese category 1 (28.93%) and predominantly were classified as NYHA Class III heart failure. There was
no significant association between BMI and outcomes among patients with decompensated heart failure. Furthermore, it
was noted that the pro-BNP values were higher in patients with lower BMI categories than in the overweight and obese
categories.
Conclusion
Obesity, while increasing the chance of developing heart failure (HF), appears to protect people who have
already been diagnosed with HF (the "obesity paradox"). This study, although not reaching statistical significance, showed
that patients with lower BMI admitted for heart failure decompensation had increased use of positive pressure ventilation
and higher mortality rates compared to obese patients. A larger sample size may be needed to show such association.
Furthermore, patients in lower BMI category had higher pro-BNP values than their counterparts consistent with previous
literature.