1.Systemic Sarcoidosis Presenting with Arrhythmia.
Eo Gin LEE ; Dong Ju HYUN ; Hee Jung LEE ; Moon Soo YOON
Korean Journal of Dermatology 2014;52(9):667-668
No abstract available.
Arrhythmias, Cardiac*
;
Sarcoidosis*
2.Cardiac sarcoidosis: two cases with autopsy findings.
W M Wan Muhaizan ; M Swaminathan ; M S Daud
The Malaysian journal of pathology 2004;26(1):59-63
Cardiac sarcoidosis is a disease of young adults. In most cases it presents with sudden death, arrhythmias, conduction disorders, heart failure or cardiomyopathy. The authors describe two cases of myocardial involvement by sarcoidosis that lead to death of the patients. Case one was a 26-year-old Indian man who was previously well and presented with sudden death. Autopsy showed nodules of sarcoid granuloma involving the heart, lungs and lymph nodes. Case two was a 47-year-old Indian lady who complained of reduced effort tolerance. Echocardiography showed that she had restrictive hypertrophic cardiomyopathy with heart failure. Seven months after initial presentation, she developed worsening of heart failure and died. Autopsy revealed involvement of the heart, lungs and liver by sarcoidosis.
Autopsy
;
Cardiac sarcoidosis
;
Sarcoidosis
;
Heart failure, NOS
;
seconds
3.Heart Failure by a Calcific Pericardial Ring: A case report.
Seong Beom HONG ; Byung Hee AHN ; Sang Wan RYU ; In Suk JUNG ; Sang Hyung KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2005;38(9):648-651
Calcific constrictive pericarditis is considered to be a nonspecific response to chronic inflammation. This disease has become rare, because the cause of it is usually tuberculosis, which has the tendency to decrease. Other possible causes of it include radiation, rheumatoid disorders, sarcoidosis, and trauma. Whatever the etiology, it can lead to cardiac tamponade by reducing cardiac diastolic filling. We report, herein, the case of a patient with heart failure by a calcific pericardial ring.
Cardiac Tamponade
;
Heart Failure*
;
Heart*
;
Humans
;
Inflammation
;
Pericarditis, Constrictive
;
Sarcoidosis
;
Tuberculosis
4.Sudden Death from Cardiac Sarcoidosis: A Case Report.
Soo Kyoung LEE ; Sun Zoo KIM ; Yoon Seup KUM ; Tae In PARK ; Sang Han LEE ; Jong Min CHAE ; Jung Sik KWAK
Korean Journal of Pathology 2003;37(5):358-361
Sarcoidosis is a systemic granulomatous inflammation with an unknown cause. The commonly involved sites are the lymph nodes, lungs, skin, eyes, and heart. Although cardiac involvement in sarcoidosis is rarely detected clinically, it is reported in 20-50% of autopsied sarcoidosis patients. Cardiac involvement is one of the most severe conditions of sarcoidosis and may cause sudden death. We report a case of a sudden death due to a massive cardiac sarcoidosis in a 43-year-old man. The microscopic examination revealed an extensive noncaseating granulomatous inflammation in the mediastinal lymph nodes and the heart with no evidence of myocyte necrosis. A special stain and molecular study excluded the possibility of other causes such as fungi or mycobacterium. The authors concluded that the cause of death was attributed to arrhythmia due to a cardiac sarcoidosis with massive involvement of the conduction system.
Adult
;
Arrhythmias, Cardiac
;
Cause of Death
;
Death, Sudden*
;
Death, Sudden, Cardiac
;
Fungi
;
Heart
;
Humans
;
Inflammation
;
Lung
;
Lymph Nodes
;
Muscle Cells
;
Mycobacterium
;
Necrosis
;
Sarcoidosis*
;
Skin
5.Management of Arrhythmias Associated with Cardiac Sarcoidosis
Korean Circulation Journal 2019;49(2):119-133
Sarcoidosis is a multisystem granulomatous disorder of unknown etiology. The annual incidence of systemic sarcoidosis is estimated at 10–20 per 100,000 individuals. Owing to the recent advances in imaging modalities, cardiac sarcoidosis (CS) is diagnosed more frequently. The triad of CS includes conduction abnormality, ventricular tachycardia, and heart failure. Atrial and ventricular arrhythmias are caused by either inflammation or scar formation. Inflammation should be treated with immunosuppression and antiarrhythmic agents and scar formation should be treated with antiarrhythmics and/or ablation, in addition to implantable cardioverter defibrillator (ICD) implantation, if necessary. Ablation can provide a good outcome, but it might require bipolar ablation if the critical portion is located mid-myocardium. Late recurrence might be caused by reactivation of sarcoidosis, which would need to be evaluated by positron emission tomography-computed tomography imaging. Risk of sudden cardiac death (SCD) in patients with advanced atrioventricular block is not low, and ICD implantation could be considered instead of a pacemaker. For risk stratification for SCD, late gadolinium enhancement by cardiac magnetic resonance imaging or program stimulation is often used.
Arrhythmias, Cardiac
;
Atrioventricular Block
;
Catheter Ablation
;
Cicatrix
;
Death, Sudden, Cardiac
;
Defibrillators
;
Defibrillators, Implantable
;
Electrons
;
Gadolinium
;
Heart Failure
;
Humans
;
Immunosuppression
;
Incidence
;
Inflammation
;
Magnetic Resonance Imaging
;
Recurrence
;
Sarcoidosis
;
Tachycardia, Ventricular
6.Imaging cardiac sarcoidosis by cardiac positron emission tomography (PET): a local experience using a high-fat, low-to-no carbohydrate protocol.
Angela S M KOH ; Tian Yue KOK ; David K L SIM ; Narayan LATH ; Ru San TAN
Annals of the Academy of Medicine, Singapore 2014;43(7):383-385
Adult
;
Cardiac Imaging Techniques
;
Cardiomyopathies
;
diagnostic imaging
;
Clinical Protocols
;
Diet, Carbohydrate-Restricted
;
Diet, High-Fat
;
Female
;
Fluorodeoxyglucose F18
;
Humans
;
Middle Aged
;
Multimodal Imaging
;
Positron-Emission Tomography
;
Radiopharmaceuticals
;
Sarcoidosis
;
diagnostic imaging
;
Tomography, X-Ray Computed
7.Recent Update of Advanced Imaging for Diagnosis of Cardiac Sarcoidosis: Based on the Findings of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography
Suyon CHANG ; Won Woo LEE ; Eun Ju CHUN
Investigative Magnetic Resonance Imaging 2019;23(2):100-113
Sarcoidosis is a multisystem disease characterized by noncaseating granulomas. Cardiac involvement is known to have poor prognosis because it can manifest as a serious condition such as the conduction abnormality, heart failure, ventricular arrhythmia, or sudden cardiac death. Although early diagnosis and early treatment is critical to improve patient prognosis, the diagnosis of CS is challenging in most cases. Diagnosis usually relies on endomyocardial biopsy (EMB), but its diagnostic yield is low due to the incidence of patchy myocardial involvement. Guidelines for the diagnosis of CS recommend a combination of clinical, electrocardiographic, and imaging findings from various modalities, if EMB cannot confirm the diagnosis. Especially, the role of advanced imaging such as cardiac magnetic resonance (CMR) imaging and positron emission tomography (PET), has shown to be important not only for the diagnosis, but also for monitoring treatment response and prognostication. CMR can evaluate cardiac function and fibrotic scar with good specificity. Late gadolinium enhancement (LGE) in CMR shows a distinctive enhancement pattern for each disease, which may be useful for differential diagnosis of CS from other similar diseases. Effectively, T1 or T2 mapping techniques can be also used for early recognition of CS. In the meantime, PET can detect and quantify metabolic activity and can be used to monitor treatment response. Recently, the use of a hybrid CMR-PET has introduced to allow identify patients with active CS with excellent co-localization and better diagnostic accuracy than CMR or PET alone. However, CS may show various findings with a wide spectrum, therefore, radiologists should consider the possible differential diagnosis of CS including myocarditis, dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy, amyloidosis, and arrhythmogenic right ventricular cardiomyopathy. Radiologists should recognize the differences in various diseases that show the characteristics of mimicking CS, and try to get an accurate diagnosis of CS.
Amyloidosis
;
Arrhythmias, Cardiac
;
Arrhythmogenic Right Ventricular Dysplasia
;
Biopsy
;
Cardiomyopathy, Dilated
;
Cardiomyopathy, Hypertrophic
;
Cicatrix
;
Death, Sudden, Cardiac
;
Diagnosis
;
Diagnosis, Differential
;
Early Diagnosis
;
Electrocardiography
;
Electrons
;
Gadolinium
;
Granuloma
;
Heart Defects, Congenital
;
Humans
;
Incidence
;
Magnetic Resonance Imaging
;
Myocarditis
;
Positron-Emission Tomography
;
Prognosis
;
Sarcoidosis
;
Sensitivity and Specificity