Objective]Summarize professor Wang Canhui′s experiences in chronic atrophic gastritis. [Methods] Summarize professor Wang Canhui′s experiences in chronic atrophic gastritis from etiology and pathogenesis, differential treatment, administered medical herbs and prescription and case. [Results]Professor Wang Canhui considers that chronic atrophic gastritis′ pathogenesis is deficiency of spleen and stomach, qi stagnation ,stomach heat and stagnation of stomach channel, the therapeutic methods of chronic atrophic gastritis is invigorating the spleen and reinforcing stomach, regulating vital energy, reducing fever and activating blood and dredging collaterals, the prescription is Jian Pi Yi Wei Decoction. The modified treatment based on clinical manifestation and the case in this article has obtained good treatment results. [Conclusion] Professor Wang Canhui′s academic thoughts and clinical experiences in chronic atrophic gastritis provide therapy ideas and high practical values in chronic atrophic gastritis.