Objective To observe the clinical feature of postural hypotension (PH) in in-hospital elderly patients. Methods Measure the supine and orthostatic blood pressure in patients were measured, and the clinical characteristics of PH and clinical incident during hospital stay were analyzed. Results (1)The PH incidence in elderly patients was 24. 11% ; (2)The incidence of systolic blood pressure PH was higher in patients with concomitant hypertension and diabetes ( P ＜ 0.05 & P ＜0.01), especially in those with relatively higher basal systolic blood pressure and diastolic blood pressure ( P ＜ 0.001); the percentage of patients taking diuretics ( P ＜ 0. 05) and calcium antagonists ( P ＜ 0. 01) were relatively higher in patients with diastolic blood pressure PH; (3)Systolic blood pressure in patients from the group with PH lowered (31 ±25) mmHg, while diastolic blood pressure lowered (11 ±15) mmHg; (4)The incidence of clinical events, including dizziness or vertigo, syncope or pre-syncope, angina pectoris or new-onset myocardial infarction, and new-onset stroke, in PH patients was distinctly higher than that in patients from the group without PH ( P ＜0. 01).Conclusion PH is a kind of common clinical manifestations in elderly patients, which tends to induce tumbling, angina pectoris, stroke, etc, and ought to be paid great attention to and taken preventive measures.

Objecfive To investigate the role of serum Insulin-like growth factor(IGF)-1,insulinlike growth factor-binding potein(IGFBP)-3 in children with Henoch-Schonlein purpura(HSP).Methods The serum concentration of IGF-1,1GFBP-3 was measured by enzyme-linked immunosorbent assay(ELISA)method in 45 acute SHP patients,40 recoverv patients and 30 healthy controls.Results The serum levels of IGF-1 [(452±183)μg/L],IGFBP-3 [(13 897±3124)μg/L] and C-reactive protein(CRP)[(20±8)mg/L]in acute phase were significantly higher than those in healthy controls(P<0.0 1)and higher than those during recovery period.The serum level of IGF-1,IGFBP-3 for the HSP patients dropped back slowly and their levels during recovery period were the same as those in healthy controls(P>0.05).The serum levels of IGF-1[(621±253)μg/L] and IGFBP-3[(18 763±3173)μg/L] were higher in the renal damage group than in the non-renal damage group(P<0.01).and the same in patients with gastrointestinal symptoms group as in patients without gastrointestinal symptoms group(P>0.05).whereas the serum level of CRP was not significantly different(P>0.05).The serum levels of IGF-1,IGFBP-3 showed positive correlation with the level of CRP(r=0.624,0.672,P<0.01).Conclusion The IGF-1 and IGFBP-3 may play an important role in the pathological mechanism of HSP.The level of IGF-1 may be used as an indicator for HSP disease activity and progression.IGF-1 mav have a close relation with the damageof renaJ system in HSP.