Objective　To study the predictability, stability and safety of laser in situ keratomileusis (LASIK) for myopia.Methods　 Five hundred and Sixty-five eyes ( 293 patients ) were treated with the SCMD corneal shaper and laser sight Compak - 200 excimer laser and followed up for more than 6 months. These eyes were divided into 4 groups according to the degrees of myopia: Group Ⅰ:-1.50～-5.75D,120 eyes; Group Ⅱ:-6.00～-9.75D,230 eyes; Group Ⅲ:-10.00～-14.75D,148 eyes and croup Ⅳ:-15.00～-26.00D,67 eyes.Results　Six months post-operatively, mean uncorrected visual acuity of each group was 1.15±0.20, 0.92±0.22, 0.69±0.24 and 0.44±0.22 respectively; The uncorrected visual acuity of 0.5 or better was 100%, 94.6%, 85.8% and 47.7% respectively; And 1.0 or better was 91.7%, 56.7%, 18.0% , 0% respectively. Mean spherical equivalent of each group was -0.14D±0.61D, -0.43D±1.20D, -0.57D±1.47D and -1.79D±2.57D respectively. There were no serious complications. Conclusion　 LASIK is an effective and safe method for reducing myopia. But the potential complications should be noticed.