1.Histopathological and Ultrastructural Changes of Brain Tissues after Experimental Complete Cerebral Ischemia in Rats
Journal of Third Military Medical University 1984;0(01):-
The selective vulnerability of brain tissues after 30 minutes of complete ischemia was observed 5, 15, and 30 minutes after ischemia and 15, 60, and 180 minutes after reperfusion in rats under optical and electron microscopies. It was found that the cerebral cortex especially the third and fifth lamina, the H1 segment of the hippocampus, and the Purkinje cells of the cerebellum were most liable to be damaged after ischemia. After reperfusion, the alterations of membrane system, nuclei and organelles were significant. The membraneous structures which contained a large amount of lipids were more severely damaged. At the same time cerebral edema was found, the severity of which was correlated with the intensity of histopathological and ultrastructural changes of the brain and the degree of blood brain barrier disruption.The findings suggest that oxygen free radicals and lipid peroxides may play an important role in the development of the damages in the brain mentioned above after reperfusion.
2.Influence of television programs on children's growth
Jianzhong WO ; Hui ZHANG ; Caimei LIU
Chinese Journal of Tissue Engineering Research 2006;10(6):187-189
AIM: To investigate the influence of television programs on children's mental growth so as to evaluate advantages and disadvantages on coordinative development of TV programs and child education.METHODS: A survey about the quality and audience rating of children's TV programs was carried out at the Developmental Psychology Institute of Beijing Normal University.RESULTS: The television programs have three main functions for children: education function (or learning function, orientation function), information function and entertainment function. Main purposes and effect for watching TV by children are: ①The major two are entertaining and getting information to enrich their knowledge, but other purposes like training thinking ability and learning skills still exist. ② Children TV programs can promote learning knowledge, skill, and academic study; develop intelligence and personality. Problems mentioned above have the age differences. However, the negative effect on child should not be neglected: ① A lot of unhealthy contents block children's healthy development. ②Watching TV for hours wastes a lot of valuable time that can be used for other important things like reading. This time-killing habit may harm children's profound thoughts and thinking ability.CONCLUSION: We should present new philosophy on children's TV programs producing. The producer should know well about children's needs and respect their requirements, including all kinds of rights and ideas, linking the entertainment function of these programs more closely with their education function and taking advantage of successful business models oversea, and inspiring organizations to produce more suitable programs.
3.Development traits of adolescents' emotion regulation ability
Jianzhong WO ; Caimei LIU ; Lingyan CAO
Chinese Journal of Tissue Engineering Research 2005;9(20):240-242
BACKGROUND: Most of previous researches on the emotion regulation ability only took children as objects.There were very few studies to investigate the adolescents' emotion regulation ability.There are fewer researches tried to study over-province large sampling to get general situation of Chinese adolescents' emotion regulation ability. Very few studies have taken emotion regulation as independent factor and explored its developmental rules OBJECTIVE:To analyze the characters of grade and gender in emotion regulation ability of Chinese adolescents DESIGN:Cross-sectional sampling survey questionnaire with adolescents as subjects SETTING:Institute of Developmental Psychology of Beijing Normal University.PARTICIPANTS:Totally 11 855 students from junior and senior high schools in Beijing,Henan,Chongqing,Zhejiang and Xinjiang, 13 high schools are included.METHODS:The present study uses "the adolescents' emotion regulaPsychology Institute, Beijing Normal University) as measuring tool to grouply test with the class as a unit. The tests in the 5 districts were completed within 2 weeks. The questionnaire is a 5-point scale.The level of emotion regulation is the mean score of the 14 items. And the higher points means higher level of emotion regulation.in emotion regulation between different grades of adolescent.RESULTS:Main effect of gender is not significant (F(1.11843)=0.040,P=0.842),while main effect of grads is significant (F(5.11843)=101.437,P=0.000),and interaction effect between gender and grades is significant (F(5.11843)=3.812,P=0.002).CONCLUSION:The emotion regulation ability of adolescents increased with the increasing grade but being stable after grade 11;the girls' emotion regulation ability exceeds the boys' gradually in grade 11,and there is no difference in the emotion regulation ability between boys and girls in grade 12.
4.Effect of ultra-filtration extract from Danggui Buxue Decoction on spleen cells in H_(22) bearing mouse inducing IL-2 and IFN-?
Qingjun LIU ; Mindi HU ; Caimei LIU ; Ting GONG
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To evaluate the effect of ultra-filtration extract from Danggui Buxue Decoction (DBD) on immune function of H22 bearing mouse and explore the mechanism through observing the effect of ultra-filtration extract from DBD on the secretion of the cytokines (IL-2,IFN-?).Methods We used membrane separation technique to extract DBD.The content of IL-2 and IFN-? in splenocyte culture supernatant was detected by enzyme-linked immunosorbent assay (ELISA),and the mRNA expression of cytokines (IL-2,IFN-?) in splenocytes was assayed by reverse transcription-polymerase chain reaction ( RT-PCR).Results The content of IL-2 and IFN-? in splenocyte culture supernatant was increased in ultra-filtration extract from DBD groups,significantly in high-dose group (P
5.Relationship and nursing between stress rise of blood glucose and the PEEL prognostic index of pa-tients with acute myocardial infarction
Chunxue LIU ; Jie ZHANG ; Youhong XING ; Caimei LI ; Xiuqin ZHU
Chinese Journal of Practical Nursing 2009;25(26):17-19
Objective To study the relationship between stress rise of blood glucose and the PEEL prognostic index of the patients with acute myocardial infarction, and provide the basis for a quick judgement and evaluation of prognosis to nurses. Methods Taking the 6.8,7.8 and 8.8 mmol/L as demarcation point to study the PEEL prognostic index in 59 patients with acute myocardial infarction, and compare the PEEL score value on two sides of each demarcation point. Results No significant difference in PEEL evaluation score when taking 6.8 mmol/L as the demarcation point, there was significant difference when taking 7.8 mmol/L as the demarcation point, PEEL score in blood glucose > 7.8 mmol/L group was higher than that of ≤7.8mmol/L group, so was when taking 8.8 mmol/L as the demarcation point. Conclusions There was instructive signifi-cance for nurses to observe a stress rise of blood glucose timely in evaluating the prognosis of patients with a-cute myocardial infarction. Nurses should strengthen disease observation and preventive nursing of admission patients whose fasting blood glucose are above 7.8 mmol/L as well their blood glucose monitoring.
6.A Study on the Seed Quality and Primary Processing of the Fresh Product of Cistanche deserticola
Caimei GU ; Dewang LIU ; Zenghui WANG ; Min CAI ; Linfang HUANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(2):306-312
The aim of this study was to evaluate the seed quality of C.deserticola and establish quality grading rules of seeds by detecting the impacts of different processing methods on the contents of the effective components of C.deserticola for optimizing the suitable processing method.The seed quality was judged by thousand-kernel weight,empty embryo rate and water content.The samples were preliminary processed by freeze-drying,natural drying and hot air circulation drying respectively,and the content of phenylethanoid glycosides was determined by HPLC-UV.The seed quality classification standard of C.deserticola was established,and the seeds were divided into three grades based on the standard.It was found that freeze-drying method was optimum,featuring less effective component loss,beautiful appearance of herbal piece,crisp texture and fast drying.In conclusion,this study laid a foundation for the quality control of the seeds of C.deserticola with the provision of scientific evidence for the initial processing of the fresh product.
7.Value of urine L-FABP in early diagnosis and progress predicting of acute kidney injury after lung transplantation
Caimei CHEN ; Zhuxing SUN ; Jing XUE ; Xiaobin LIU ; Liang WANG
The Journal of Practical Medicine 2017;33(1):26-29
Objective To investigate the value of urine liver?type fatty acid?binding proteins(L?FABP) for early diagnosis and progress predicting of acute kidney injury(AKI)after lung transplantation. Methods Urine L?FABP and Scr blood samples in perioperative periods of 119 lung transplant recipients (hospitalized between 2013?2014)were involved in the research. Patients were divided into AKI group and non?AKI group according to KDIGO. Changes in urine L?FABP and Scr of two groups at various time points were recorded. Results Of 119 patients,57 developed AKI after surgery. Urine L?FABP from 0 h to 48 h in the two groups increased significantly, and the difference at 6 h to 48 h between the two groups is significant. In terms of diagnostic value,ROC area of urine L?FABP at 6h is 0.818. When 2254.52 ng/mg Cr was taken as diagnostic dividing line ,sensitivity and specificity was 0.782 and 0.814. In predicting AKI progression ,AUC below AUC of urine L?FABP 0.852. When 4313.17 ng/mgCr was taken as diagnostic dividing line ,sensitivity and specificity was 0.867 and 0.700. Conclusion Urinary L?FABP appears to be a sensitive and specific marker of AKI in lung transplant recipients ,could be a biological marker in the early diagnosis and progression tendency of AKI.
8.Immunomodulation of polypeptides from Chlamys farreri(PCF) in mice
Caimei ZHANG ; Hongmei ZHANG ; Yejun YU ; Xiaopin LIU
Chinese Journal of Marine Drugs 1994;0(03):-
Objective To investigate the immunomodulation of PCF on the immunosuppressed mice. Methods The immunosuppressed model was established by injection of dexamethasone (DEX) intraperitoneally. Effects of PCF on the immunity were studied by the observation of morphology of immune organ, the analysis of T lymphocytes subsets and the measurement of lymphoproliferative ability. Results PCF could markedly improve the low immunoreaction of immunosuppressed mice caused by DEX. It was showed that the white pulp of spleen was enlarged, the quantity of T lymphocytes of the peripheral blood was increased and the response of lymphoproliferation to ConA was enhanced in the test group compared to those in the model group. Conclusion PCF had the abilities to up-regulate the immunity in vivo,which may be due to its influences on the peripheral mature immunocytes.
9.Effect of nursing ward rounds with head nurses′tutoring and commenting
Xiaojin LI ; Xiaobei LIU ; Liwen ZENG ; Lu LIU ; Caimei ZHOU ; Liangying JIANG ; Enjin HU
Modern Clinical Nursing 2016;15(8):62-66
Objective To explore the effect of head nurses′tutoring and commenting on nursing ward round. Methods The nursing ward rounds performed during August 2013 to July 2014 were assigned as the control group and those nursing ward rounds during August 2014 to August 2015 as observation group: in the former group routine nursing ward rounds were done once a week and in the latter the rounds were performed by head nurses′tutoring and commenting once every week. The two groups were compared in terms of examination performances of nursing ward rounds, doctors′ and nurses′ satisfaction degree, nurses′ and student nurses′evaluation on the ward rounds and their critical thinking ability. Results The examination performances and the satisfaction degree in the observation group were significantly higher than those of the control group (P<0.05). The nurses in the observation group thought the head nurse′s commenting at ward rounds could be more effective than those from the control group in their improvement of theoretical knowledge and clinical ability (P<0.05). In terms of critical thinking by California Critical Thinking Disposition Inventory-Chinese Version), the total score and the scores on its dimensions in the observation group were significantly higher than those of the control group. Conclusion The nursing ward rounds by head nurses′tutoring and commenting can help the nurses to strengthen their ability in nursing ward rounds and improve their theory and clinical practice so that the nursing quality is improved.
10.Construction and application of the health appropriate technology database in Zhejiang Province
Xin WEN ; Qifeng ZHANG ; Caimei FANG ; Wei ZHU ; Yi LIU ; Renzhi LIN ; Zhijun XIA
Chinese Journal of Medical Science Research Management 2017;30(1):38-41
Objective Analyzing the construction process and application of health appropriate technology database in Zhejiang province and proposing related considerations and recommendations for the database construction.Methods To design and construct the technology database system,and using excel software to calculate statistic data.Results Established a health appropriate technology database,which contains 826 technologies that can be selected and promoted by the demonstration bases in the whole province.Conclusions The establishment of the technology database increased the efficiency of health appropriate technology transformation at the provincial level,and also provided a reference for the national-wide generalizing of health appropriate technology.