Objective to observe the clinical curative effect of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction. Methods 100 patients suffered peptic ulcer are devided into two groups in random,each for 50. The control group take the western common treatment, the treatment group is based on the control group combination with the Shen-Qi-Jian-Wei decoction made by self.a course of treatment is 50days. Results the total effective power of the control group is 94.0%, the total effective power of the treat group is 72.0%, the total effective power comparision of two groups isobvious,the diffierence has the stastitical meanings.Conclusion the treatment of peptic ulcer based on the Shen-Qi-Jian-Wei decoction made by self is superior to the pure western medicine group.

Objective To study the clinical curative effect of ChaiShaoBuPi decoction in the treatment of functional dyspepsia. Methods 100 patients with functional dyspepsia were divided into a treatment group and a control group randomly. The treaunent group was treated with modified ChaiShaoBuPi decoction and the control group was treated with dornperidone. Both groups were treated for one therapeutic course of four weeks. Results The total effective rate in the treatment group and the control group was 90.00% and 70.00% respectively. The difference between the two groups showed statistical significance (P<0.01) . Conclusion ChaiShaoBuPi decoction has good therapeutic effect in treating the disease of fanctional dyspepsia.

OBJECTIVE:To evaluate the economic effectiveness in different chemotherapeutic schemes for acute mononu?clear leukemia(M 5 ).METHODS:Using pharmacoeconomic cost-effectiveness analysis,three chemotherapy schemes for M 5 we_ re compared.RESULTS:Among three schemes,DAE scheme was the best one.CONCLUSION:The results show that phar?macoeconomics plays an important role in optimizing therapeutic scheme,in helping the physician to choose the best therapeutic plan in making clinical decision.

Spinal cord injury (SCI) is a common traumatic disease. SCI causes nutritional and metabolic abnormalities including malnu-trition and overnutrition. This article reviewed nutritional metabolism assessments, the changes and reasons after SCI. Spinal Nutrition Screening Tool (SNST) and Malnutrition Universal Screening Tool (MUST) are commonly used to evaluate malnutrition in adult. Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) is used to evaluate malnutrition in child. Body mass index, waist circumfer-ence and dual-energy X-ray are used to evaluate overnutrition. SCI causes increasement of total caloric intake, disturbance of carbohydrate metabolism, disturbance of fat and protein metabolism, increasement of metabolic syndrome incidence, high risk of coronary heart disease, and abnormal bone metabolism. Individual diet program should be provided to SCI patients for balanced nutrition. Periodic assessments are also necessary.

Objective To study the effect of lidocaine combined with local anesthesia and psychological intervention in induced abortion.Methods200 cases of artificial abortion in our hospital from March 2015 to August 2016 were selected as the research object and randomly divided into control group and experimental group,with 100 cases in each group.The control group was treated with lidocaine for local anesthesia,direct abortion,and the experimental group was given lidocaine local anesthesia and psychological intervention.The pain and satisfaction index of the two groups were compared.ResultsAfter the treatment, the satisfaction rate of cervical dilatation in the experimental group was 93 cases was 93% higher than that in the control group, and the difference was statistically significant (P<0.05).The number of patients with grade Ⅱ pain in the experimental group was 12, and the number of patients with grade I pain was 87.In the control group, the number of patients with grade Ⅱ pain was 25, and the number of patients with grade Ⅱ pain was 57.But the control group was significantly lower than the experimental group, with statistical difference (P<0.05).In the control group, patients with grade Ⅱ pain were significantly higher than those in the experimental group, the number of patients with grade I pain was significantly less than that in the experimental group, and the difference was statistically significant (P<0.05).There was no significant difference in the operation time and blood loss between the control experimental and the control group.ConclusionThe application of lidocaine local anesthesia combined with psychological intervention can effectively relieve the pain of patients and improve the therapeutic effect.It has the value of clinical popularization and Application.

Objective To investigate the effects of survivin antisense oligonucleotide (ASODN) on human uterine endometrial cancer HEC-1B cell line. Methods The experiment included four groups: blank control group (blank), lipofectin control group (Lip), oligonucleotide (SODN) control group and antisense oligonucleotide (ASODN) test group. Artificially synthesized survivin antisense oligonucleotide was transfected for 48 hours into endometrial cancer cells using liposome after cultivation. The expression of survivin protein was determined by Western blot, and the cellular apoptotic rate was tested by flow cytometric analysis. MTT method was used to assay cellular growth rate. Results In comparing with the blank, Lip and SODN control groups, survivin protein expression was obviously decreased in HEC-1B cancer cells after transfected with survivin ASODN. The apoptotic rate and proliferation inhibition rate in ASODN test group were significantly higher than that in the control groups (P<0.05). There was no significant difference between other control groups (P>0.05). Conclusions The expression of survivin is decreased in endometrial cancer cells after ASODN transfection. Survivin ASODN causes cellular apoptosis and inhibits the proliferation of HEC-1B cells. It may be a useful gene therapy for endometrial cancer.

Objective To investigate the effects of total saponins of Panax ginseng(TSPG) combined with erythropoietin(EPO) or granulocyte macrophage colony stimulating factor(GM CSF) on the differentiation of K562 cells. Methods Cells were cultured in vitro . Morphologic changes of cells were observed with light microscope and electron microscope. The levels of hemoglobin, peroxidase, non specific lipase ? NAE in cells were detected respectively by benzidine staining, peroxidase(POX) staining and ? NAE cytochemical staining. Levels of cell surface differentiation antigens CD15, HIR2, EPO R and GM CSF R were determined by immunocytochemistry. Results TSPG combined with EPO or GM CSF resulted in more mature morphological features of K562, increased expressions of hemoglobin and myeolperoxidase in K562 cells, and enhanced expressions of cell surface differentiation antigens CD15, HIR2, EPO R and GM CSF R. Conclusion TSPG combined with cytokine EPO or GM CSF can induce more mature differentiation of K562 cells.

[Objective] This paper discusses the perioperative nursing of rectal cancer patients treated with laparoscopy. [Methods] A total of 35 rectal cancer patients with laparoscopic treatment were included in the sample. Patients were provided with preparative psychological care, and were guided in postoperative nursing including diet, position, stoma, activities and other relevant conditions. Also likely complications were under careful observation and care.[Results] Al 35 surgeries were smoothly performed with no nursing-related complication. Fol ow-up data reported satisfying postoperative recovery and a good quality of life. [Conclusion] For rectal cancer patients who receive laparoscopic treatment, safe and effective perioperative nursing contributes directly to better postoperative recovery.

Objective To evaluate the effect of dexmedetomidine on perioperative cellular immune function in elderly patients undergoing radical operation for gastrointestinal cancer.Methods Forty ASA physical status Ⅰ-ll patients,aged 65-82 yr,weighing 43-80 kg,undergoing elective radical operation for gastrointestinal cancer,were randomly divided into 2 groups (n =20 each) using a random number table:control group (group C) and dexmedetomidine group (group D).Anesthesia was induced with sufentanil,propofol and rocuronium and maintained with inhalation of sevoflurane,infusion of propofol and intermittent iv boluses of sufentanil and rocuronium.A loading dose of dexmedetomidine 0.5 μg/kg was infused intravenously over 10 min starting from 30 min before induction of anesthesia,followed by infusion at 0.3 μg· kg-t· h-1 until the end of operation in group D.The equal volume of normal saline was given in C group.Venous blood samples were obtained at 30 min before induction,and 1,24 and 72 h after operation for determination of plasma concentrations of interferon (IFN)-γ,interleukin (IL)-2,IL-10 and IL-4 by ELISA.Results Compared with group C,the plasma concentrations of IFN-γand IL-2 were significantly increased,and the plasma concentration of IL-10 was decreased at each time point after operation (P ＜ 0.05),while no significant change was found in the plasma concentration of IL-4 at each time point after operation in group D (P ＞ 0.05).Conclusion Dexmedetomidine can improve the perioperative cellular immune function in elderly patients undergoing radical operation for gastrointestinal cancer.

Objective To investigate the relationship of iPTH levels, calcium and phosphorus metabolism with cardiovascular event status in the chronic renal failure (CRF) patients. Methods This article retrospectivly studied the clinical and laboratory data of 87 CRF patients. 66 patients of A group didnt occur cardiovascular events,and 21 cases of B group occurred cardiovascular and cerebrovascular events. This article analyzed iPTH levels,serum calcium, phosphorus, calcium and phosphorus product and therelationship between cardiovascular and cerebrovascular events between the two groups. Results Decreased iPTH,increased serum C reactive protein and increased lipoprotein(a) had relationship with cardiovascular and cerebrovascular events in patients with chronic renal failure,but calcium,phosphorus,calcium and phosphorus product has nothing to do with the cardiovascular and cerebrovascular events. Cardiovascular and cerebrovascular events increased significantly in dialysis patients than in non - dialysis patients. Conclusiou Chronic renal failure patients on dialysis levels of serum iPTH, CRP level, LP(a) level and dialysis could lead to cardiovascular and cerebrovascular events.