People′s misunderstandings about the radiological check in health examination: Equalize the price of the medical check equipment with the accuracy of the check .The health examinees′misunderstanding about the harm which X-Ray can cause , thinking that low dose chest CT only can do very little harm to human body .The health examination unit makes the rate of finding out early lung tumor a main basis of assessing a medical personnel ′s achievement , which caused medical staff go against epidemiological laws when diagnosing tiny nodules .Misun-derstandings about some biological features such as the scale or the growing speed of the nidus , and laying exces-sive importance on the check accuracy , which caused some examinees received excessive X -Ray, overdiagnosis and overtreatment .So, people must treat radiological check in health examination rationally and dialectically , in order to further realize the legitimation and rationalization of radiological check .

As a part of the central nervous system,retina shares many characters of the brain,including many of the functions and dysfunctions of microglia.Microglia plays important roles in multiple inflammatory procedures and degenerative diseases of the central nervous system and retina.Retinal microglia is involved in ocular inflammatory,age-related macular degeneration and diabetic retinopathy.These cells have also been identified in brain tumor and retinoblastoma.They can secrete various cytokines and growth factors that may contribute to the successful immune evasion and therefore promote the growth and invasion of tumor.To better understand the function of microglia is essential for us to develop the immune-based treatment strategies against central nervous system tumor and retinoblastoma.

ObjectiveTo evaluate the effect of health education combined with psychological counseling on mental state of patients with coronary heart disease complicated with anxiety and depression. Methods70 cases of patients with coronary heart disease with anxiety and depression were divided into the observation group and the control group with 35 cases in each group.The control group received regular professional care,while the observation group was given health education combined with psychological counseling on the basis of regular professional care.The SAS and SDS score was compared between the two groups. ResultsAfter treatment,SAS and SDS score of two groups apparently improved.After treatment,SAS and SDS score of the observation group was less than the control group. ConclusionsHealth education combined with psychological counseling for patients with coronary heart disease complicated with anxiety and depression can effectively alleviate the anxiety and depression emotion of patients and increase life quality of them.

A mechanical shimming method and device for permanent magnet of MRI system has been developed to meet its stringent homogeneity requirement without time-consuming passive shimming on site, installation and adjustment efficiency has been increased.
Magnetic Resonance Imaging ; instrumentation ; methods ; Magnets

This paper analyzes the influence of modern enterprise system on managerial mechanism and industrial management of pharmaceutical enterprise, and the countermeasure that should be adopted by enterprise are discussed as well.

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder of hematopoietic stem cells due to acquisition of somatic mutations.Somatic mutations in phosphatidylinositol glycan class A (PIGA) account for intravascular hemolysis and other PNH manifestations,but the pathophysiology of clonal expansion of PNH cells cannot be elucidated clearly.PNH is closely related to aplastic anemia and myelodysplastic syndromes.Today,the gold standard for PNH is flow cytometry to detect the absence or severe deficiency of glycosylphosphatidylinositol (GPI)-anchored proteins on white and red blood cells.However,PNH diagnosed by phenotype is a group of heterogeneous disease in pathogenesis.Eculizumab,a first-in-class monoclonal antibody that inhibits terminal complement,is highly effective in stopping intravascular hemolysis and improving quality of life.Further research on the pathogenesis of PNH would be helpful to understand the underlying reasons for PNH phenotype cells in different patients,improve differential diagnosis and more targeted and specific therapy.Research progress in recent years will be reviewed in this article.

Raltitrexed is a specific inhibitor of thymidylate synthase,and has been confirmed that ralti-trexed has no cross tolerance with 5-fluorouracil.Studies have shown that raltitrexed-based combination chemo-therapy has a beneficial effect on the treatment of advanced gastric cancer,and well tolerance,which is worthy of clinical use.

Progress toward improving management of myelodysplastic syndromes (MDS) occurred every year.This review focused on the new developments of classification,diagnoses,prognostic stratification and therapy on MDS in recent five years.In addiction,a brief introduction of pediatric MDS was presented here.All this were for a better exploration in the future.

With the progress of medical research,more and more inherited and congenital factors predisposing to hematologic malignancies have been revealed,which have brewed into a hot topic of the 56th American Society of Hematology (ASH) annual meeting in 2014.Correctly understanding and interpreting these innate susceptible factors will be of great significance in improving the treatment in patients and prevention or early detecting of cancers in individuals carrying these factors.Research progress in this area will be introduced together with the authors' research in this article.

Viral infections remain a major cause of morbidity in patients with immunodeficiency,such as recipients of hematopoietic stem cell transplantation (HSCT).Adoptive transfer of donor-derived virusspecific cytotoxic T lymphocytes is a strategy to restore virus-specific immunity to prevent or treat viral diseases and has been tested in the clinical setting for more than 20 years.The 55th ASH annual meeting reported lots of basic and clinical experience about CTL and summarized lots of trails to evaluate it,which will give us some new thought about the antivirus therapy after HSCT.