thymus.It is not clear why and how these distribution exist,which is possibly correlated to recruitment,homing,subset,and microenvironment of NK cells in each tissue or organ.

The mucosal tissues form the interface between the outside world and the sterile environment of the body.Innate immunity plays a critical role in the maintenance of mucosal homeostasis.Recently,a new subset of innate immune cells named NK-22 has been discovered to reside at tonsil and intestine both in human and mice.NK-22 cells share features with both natural killer (NK) cells and lymphoid tissue-inducing (LTi) cells.NK-22 cells express a variety of NK cell receptors and phenotypically resemble that of immature NK cells (iNKs).However,they are quite different from NK cells in function and development.NK-22 cells lack conventional NK cell cytotoxic function and produce IL-22 instead of IFN-?.It is currently considered that NK-22 cells are not a subset of NK cells.They develop from LTi cells and the development process depends on ROR?t and commensal microflora.NK-22 cells are involved in immune protection against the pathogen Citrobacter rodentium.The IL-22 secreted by NK-22 cells contributes to epithelial cell resistance to injury and mucosal tissue repair after microbial infection.

Based on a clinical and radiological study of radiation injuries of the bones in the 17 cases, the relationship between the osseous changes and the radiation dosage and between the time from radiation therapy and the onset of the radiographic osseous changes were discussed. The authors found that the degree of local skin infection might determine the type of its underneath osseous injuries, i. e. being either "septic" (osteomyelitic) or "aseptic" (bone atrophic) radionecrosis, and it might also determine the time when the osseous changes appeared on the radiogram. It was found that radiation injuries of the bone could be distinguished from bone metastases. The authors suggest that a regular X-ray follow-up of the bones that had received a heavy dose of radiation should be made in order to reveal bone atrophy as early as posible and to remind the patient to avoid any trauma and infection.

The placement of stent in coronary artery reduces the restenosis rate of percutaneous transluminal coronary angioplasty(PTCA),but the restenosis has perplexed us so far. May be a novel drug coated stent will bring us a new hope in the coming years.

The role of apply and study of techniques of intelligent building(IB) is reviewed in recent years, although cultural heritage report way lots of relevantly IB, construct the report way of the medical treatment building intelligent is the less, right various project of author take into to categorize, for development and design of the hospital intelligent building of outpatient and emergency department provides the reference.

Objective:To analyze whether medical insurance and environment protective behaviors could alleviate the influence of environmental pollutions on individual health status.Methods:Using the data of CGSS(2010) to conduct the empirical analysis based on Logit model.Results:Residents' choice on medical insurance and environment protective behaviors could alleviate the damage of environmental pollutions on health.Compared with the young and middle-aged,the elderly effectively alleviated the damage brought by environment pollutions through participating medical insurance.Compared with the low-educated individuals the high-educated inviduals' choices for environment protective behavior could effec tively release the damages brought by environmental pollutions.Conclusion:The government should advocate environmental protective behaviors,provide full coverage of medical insurances to let individuals alleviate the damages of environmental pollutions by their rational choice.More emphasis should be paid to the damage of environmental pollutions on the elderly group and individuals with lower education.

Neonatal hypoglycemia is a common clinical disease.Hypoglycemia can lead to severe acute and long-term dysfunction of nervous system.The several aspects of neonatal hypoglyccmia such as the definition,diagnosis of brain injury,risk factors,treatment,detection method and long-term follow-up were reviewed.

Amino acids (AA) as substrates of gluconeogenesis could promote endogenous glucose production.Some AA can enhance insulin secretion. Recently,many studies have found that some AA can also activate mammalian target of rapamycin-S6 kinase 1 ( mTOR-S6K1 ) pathway,resulting in maintaining pancreatic β cell function on one hand,and on the other hand,inhibiting insulin signal transduction of insulin-sensitive cells and thus causing insulin resistance.

Objective To evaluate the quality of life (QOL) in continuous ambulatory peritoneal dialysis (CAPD) patients and analyze the non-medical factors influencing QOL in order to explore the possible way to improve QOL in peritoneal dialysis (PD) patients.Methods Seventy-nine chronic renal failure patients treated with PD included in the present study.Investigated their age,sex,working status,education,medical burden and family support.Patients' QOL was evaluated by international questionnaire-KDQOL/SF-36.Patients' anxiety/depmssion status was evaluated by Hamilton depression questionnaire.Results (1)The SF-36 with its eight scales of CAPD patients were markedly lower than ordinary people (P＜0.05 or＜0.01).(2) Comparing with those on work,the patients without work got lower SF-36 scores[(45.78±16.93) seores vs (32.65±12.26) scores,P＜0.05].Comparing with those who had medical care,the patients without medical care got much lower SF-36 scores [(49.62±13.20) scores vs (33.85±6.24) scores,P＜0.05].Patients with higher income had better QOL.(3) Patients cared by their children and companion had the higheat SF-36 [(68.33±14.73) scores],while those cared by nursemaid or themselves had the lowest [(27.98±15.77) scores].(4) Among the 79 patients,43 patients (54.4%) were anxiety and 12 patients (15.2%) were depression.QOL was negatively correlated with anxiety index and depression index.Conclusion The QOL of CAPD patients are remarkably low,which is deeply influenced by many non-medical factors such as working status,medical burden,family support and emotional status.

Objective To observe the cognitional differences between teachers and students concerning teaching objective,curriculum,teaching methods and effect and teaching reform and to pro-vide references for teaching reform. Methods Medical humanistic questionnaire was designed to survey teachers and students. Data were processed by SPSS 18.0 and were analyzed by Chi-square. P value smaller than 0.05 signifies significant differences. Results There were significant differences in cognition of medical humanistic ability,emotion controlling ability,curriculuma provision and teaching methods between teachers and students.12.9% teachers and 41.3% students considered that the opportunity of medical humanistic practice was plenty while 55.7%teachers and 35.3%students thought that the univer-sity attached little importance to medical humanistic teaching. Conclusions Key points of humanistic reform include making clear the teaching objectives,emphasizing practice of medical humanistic teach-ing,improving curriculum and deepening appraisal reform.