Objective To evaluate the clearance effect of hemodiafihration(HDF) and hemopeffusion combined with hemodialysis( HP + HD) on serum calcium,phosphorus and parathyroid hormone in patients with uremia.Methods Fifty-eight uremia patients treated with maintenance hemodialysis in our hospital from May 2009 to October 2010 were randomly divided into two groups:HDF group (n =29)and HP + HD group (n =29).Patients in HP + HD group underwent HD conventional treatment 5 times and HP + HD.treatment once every two weeks,while those in HDF group underwent HD treatment 5 times and HDF treatment once every two weeks.All subjects were treated for 12 weeks.Serum calcium,phosphorus and parathyroid hormone were detected and analyzed before and after the treatment.Results After therapy,the serum calcium ( [ 2.41 ± 0.32 ] mmol/L v.s.[ 2.22 ± 0.35 ] mmol/L,t =5.47,P ＜ 0.01 ),phosphorus( [ 1.98 ± 0.34 ] mmol/L v.s.[ 1.70 ± 0.31 ] mmol/L,t=8.13,P ＜0.01)and parathyroid hormone( [645.19 ± 184.52] ng/L v.s.[296.79 ± 103.54]ng/L,t =6.54,P ＜ 0.01 ) levels of HP + HD group decreased significantly.Similarly,the serum calcium ( [ 2.43 ± 0.33 ] mmol/ L v.s.[ 2.32 ± 0.37] mmol/L,t =6.72,P ＜ 0.01 ),phosphorus ( [ 1.97 ± 0.36 ] mmol/L v.s.[ 1.83 ± 0.35 ] mmol/L,t =6.47,P ＜ 0.01 ) and parathyroid hormone ( [ 639.47 ± 208.73 ] ng/L v.s.[ 409.91 ± 152.72 ] ng/L,t =5.27,P ＜ 0.01 ) levels of HDF group also decreased significantly.Comparison of the two blood purification methods indicated that the clearance effect of HP + HD on serum calcium,phosphorus and parathyroid hormone was significantly better than HDF( t =4.24 and t =7.24,P ＜ 0.01 ).Conclusion Both HDF and HD + HP could clear serum calcium,phosphorus and parathyroid hormone effectively,while the clearance effect of HD +HP is better than HDF.

Objective To discuss the clinical effects and mechanism of using transcervical resection of adhesion (TCRA)combined with reinforcing kidney and removing stasis to treat intrauterine adhesion.Methods From June 2014 to December 2014,70 patients with intrauterine adhesion were selected in our hospital and randomly divided into the observation group and the control group (35 cases in each group).All the two groups had TCRA.The observation group had reinforcing kidney and removing stasis method,while the control group had climen treatment. Both two groups had 3 menstrual cycles of treatment.After treatment,the overall curative effect,menstruation recovery analysis caused by intrauterine adhesions degree before and after treatment and the endometrium,serum E2,FSH and uterine artery blood flow pulsation index and resistance index of the two groups were recorded and compared.Results After 3 menstrual cycles after treatment,the total effective rate in the observation group was 94.3%,which was significantly higher than 7 7 .1 % in the control group (χ2 =4 .2 0 0 ,P <0 .0 5 ).And the primary symptom menstruation recovery rate in the observation group was 97.2%,which was significantly higher than 82.8% in the control group (χ2 =3.968,P <0.05).After treatment,the IUA integral scores in the two groups had significant reduction (t =6.50,3.36,all P <0.05),but the observation group decreased more obviously (t =3.82,P <0.05). After treatment,RI in the two groups declined more significantly compared with before treatment (t =2.23,1.70,all P <0.05),but PI without statistically significant difference compared with before treatment (t =0.38,0.65,all P >0.05).After treatment,the uterine artery blood flow of PI,RI had no statistically significant differences between the two groups (t =0.42,0.56,all P >0.05).During treatment,the heart,liver,kidney,blood and urine routine in two groups were all within the normal range,and the incidence rate of adverse reactions was 11.4% in the control group, which was significantly higher than 2.8% in the observation group (χ2 =3.968,P <0.05 ).Conclusion Using TCRA combined with reinforcing kidney and removing stasis to treat intrauterine adhesion after treatment has better curative effects,which could promote the menstrual cycle of uterine cavity formation and recovery.Its mechanism may be related to uterine blood flow perfusion improvement and womb restoration.

Percutaneous mechanical circulatory support (PMCS) devices are effective in the treatment of patients with cardiogenic shock and acute decompensated heart failure, as a bridge to the recovery of heart function or further treatment. The intra-aortic balloon pump (IABP) is now the most widely used PMCS. New PMCS devices including Transseptal device of Tandem-Heart, transaortic valve device of Impella and extracorporeal membrane oxygenation (ECMO) might provide more effective hemodynamic supports. Doctors should choose appropriate PMCS devices and their working modes, according to patient's clinical conditions, based on the working principles and hemodynamic effects of the devices, in order to achieve the best effects and help patients live through the crisis of diseases.

Objective To study the expression of carbonic anhydrase 9(CA9) in clear cell renal carcinoma(ccRCC), and the relationship between the expression and recurrence .Methods Paraffin-embedded tissues from 53 ccRCC cases were collected during the past 3 years,and immunohistochemistry was used to detect the expression of CA 9.Fifty-three cases were followed up to evaluate the disease-free survival ( DFS) and recurrence .Association of CA9 expression with recurrence was then analyzed .Results Localized RCC recurred in eleven cases , the median DFS was 10 months, the integral optical density ( IOD) of the recurrent cases was 230 879 .84 ±64 878 .72 while the IOD of the thirteen nonrecurrent cases was much higher,444 993.31 ±146 946.27(P<0.01).Conclusion There might be a positive correlation between the low expression of CA9 and the recurrence of ccRCC .CA9 may help predict the ccRCC patients ’ prognosis.

Child ; Child Behavior Disorders ; etiology ; Cognition Disorders ; physiopathology ; Humans ; Sleep Apnea Syndromes ; psychology

Objective To investigate the changes of detection rates of IL-2,IL-6 and serum anti-Chlamydia immunodominant protein antibody in the patients with Chlamydia trachomatis genital tract infection.Methods Sixty women with genital tract infection (CT group) and 60 healthy women (control group) were selected in our hospital from January to May 2016.The serum levels of IL-2,IL-6 and anti-Chlamydia immunodominant protein and IL-2 and IL-6 levels in cervical secretions were detected in the two groups.Results The IL-2 and IL-6 levels of serum and cervical secretions in the CT group were significantly higher than those in the control group,the difference was statistically significant (P<0.05);the positive detection rates of serum OmcBc antibody,Pgp3 antibody,HSP60 antibody and CTT841 antibody in the CT group were 45.00%,75.00%,23.33% and 38.33% respectively,which were significantly higher than those in the control group,the difference was statistically significant (P<0.05).Conclusion The positive detection rates of IL-2,IL-6 and serum anti-Chlamydia immunodominant protein antibody in the patients with genital tract Chlamydia infection are significantly increased,which has some guiding significance for clinical diagnosis and treatment.

Breast cancer is one of the most common malignant tumor for women, and early and accurate diagnosis of the breast diseases may improve the therapy and prognosis. MRI gains advantages in the diagnosis of the breast diseases, and thus is an important tool for the imaging diagnosis of the breast. The examination modes of MRI were introduced for the diagnosis of the breast cancer, especially the application in high risk population. The limit and research progress of MRI were analyzed for breast cancer staging, pre-operative examination, therapeutic effect assessment for radiotherapy and chemotherapy, the relationship between the markers and imaging findings.

Objective To understand the plasma Platelet Microparticiles(PMPs)level and its clinical significance in patients with type 2 diabetes mellitus(T2DM).Methods Venous blood samples were obtained from 96 of T2DM patients and 30 of non-diabetic control subjects.PMPs,CD61P positive on platelets,were quantified by flow cytometry.Meanwhile,plasma levels of PLT,FPG,TC,TG,HDL-C,LDL-C and LP(a)were detected,as well as the levels of MA and TRF from urine samples.Results PMPs counts were significantly greater in 2 year or up 2 year groups than in controls.PMPs count was associated with levels of urine MA and TRF,but not related with other indexes.Conclusion PMPs may be a marker of microvascular disease in Type 2 diabetes.

Objective To explore the effects of music games thematic curricula on preschool children with intellectual disabilities. Methods 30 children with intellectual disabilities accepted music games thematic curricula (experiment group, n=15) or routine thematic curricula (control group, n=15) respectively. They were assessed with the Scales of Learning Attitude, Scales of Emotive Behavior, Scales of Communicational Ability, and Scales of Social Skill before and after 20 weeks of curricula. Results The experiment group performed better in learning attitude, emotive behavior, communicational ability, and social skill than the control group (P<0.001). Conclusion Using music games in thematic curricula can not only improve the mood and behavior of the preschool children with intellectual disabilities apparently, but also inspire their learning interest, develop their communicational and social abilities.

From April 1987 to December 1995,146 patients (Pts) with coronary artery disease (CAD) underwent PTCA. There were 133 male & 13 female with a mean age of 58 (33-76) yrs. The total lesions were 425 including 34 (8.0%) lesions in type A,214 (50. 4%) in type B &. 91 (41. 6%) in type C. The PTCA target lesions were 339 with 37 (8. 7%) total occlusion lesions. Twenty-two lesions had severe dissection following balloon dilatation & successful coronary stenting were done immediately. Another 40 stents were implanted for de novo severe proximal vessel lesions. Five Pts underwent rotational ablation & 3 underwent direct coronary atherectomy. Success dilatation was 95. 9% of total Pts & 95. 6 % of total lesions. The average stenosis in diameter reduced from 89. 1% to 9.8% (P