1.Analysis of causes and inducement in 126 aged patients with acute heart failure
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(4):431-433
Objective:To explore causes and inducement in aged patients with acute heart failure (AHF)and provide reference for clinical prevention and treatment of AHF.Methods:A total of 213 AHF patients,who hospitalized in Shenzhen Shekou People's Hospital from Jan 2010 to Dec 2013,were enrolled and divided into aged group (n=126) and youth and middle-aged group (n=87),incidence of causes and inducement were compared and analyzed between two groups.Results:Compared with youth and middle-aged group,there were significant rise in percentages of cor-onary heart disease (17.24% vs.72.22%)and hypertension (10.34% vs.34.13%),and significant reductions in percentages of valvular heart disease (12.70% vs.4.76%),cardiomyopathy (35.63% vs.7.14%)and congenital heart disease (26.44% vs.5.56%)in aged group,P <0.01 all.For the cause aggregation,percentage of multi-cause in aged group was significantly higher than that of youth and middle-aged group (39.68% vs.17.24%),while percentage of single-cause in youth and middle-aged group was significantly higher than that of aged group (82.76%vs.60.32%),P <0.01 both;the most frequent inducement was infection in both group,but there was no signifi-cant difference between two groups,P >0.05. Conclusion:Cause constitution is different among patients with acute heart failure and different age.The cause is complex and it′s mainly is coronary heart disease and hypertension in aged patients,and multiple factors work together.The target prevention and treatment should be taken according to the actual condition.
2.The discussion of Shuanghuanglian ultrasonic-atomization way for non-gonococcal conjunctivitis in the newborns attaching 56 examples for analysis
Chinese Journal of Primary Medicine and Pharmacy 2008;15(5):764-765
Objective To discuss the non-antibiotic Chinese medicine therapy for the non-gonococcus conjunctivitis in newborns, and reduce the use of antibiotic and the production of bear-medicine-bacterium. Methods 0.9%-sodium chloride was used as the inoculation fluid, Shuanghuanglian (freezing and drying) was uscd as dissolution injection. Dexamethasone sodium phosphate injection 1ml: 5mg was added, mixed-fluid 16ml was matched to spray the eyes after ultrasonic-atomization equipment atomizes. Results 56 examples 103 eyes which had the nongonococcus conjunctivitis in newborns were treated only with the injection with the Shuanghuanglian dexamethasone sodium phosphate injection mixed with the fluided ultrasonic-atomization equipment atomizes and the total effectiveness reached 97.08%. Conclusion The Shuanghuanglian-ultrasonic-atomization way to treat non-gonococcal conjunctivitis in the newborns is safe and effective.
3.Literature Analysis of 97 ADR Cases Induced by Fat Emulsion Injection
China Pharmacy 2007;0(32):-
OBJECTIVE: To explore the regularity and characteristics of ADR cases induced by Fat emulsion injection, and to provide reference for rational use of it. METHODS: Retrieved from Chinese medical science periodicals from Jan. 1990 to Apr. 2010, 97 ADR cases induced by Fat emulsion injection were analyzed statistically. RESULTS: Main clinical manifestations of ADR cases induced by Fat emulsion injection were allergy reaction, followed by fat overloading syndrome, central nervous system reaction. The majority of ADR cases broke out in the first time of medication within 2 hour. CONCLUSION: It is essential for clinical practitioners to master the characteristics of ADR cases caused by Fat emulsion injection so as to promote safety of drug use.
4.Role of Helicobacter pylori Eradication in Diarrhea-predominant Irritable Bowel Syndrome
Chinese Journal of Gastroenterology 2017;22(8):482-485
Background:Irritable bowel syndrome (IBS)is a commonly seen functional intestinal disorder. The association between Helicobacter pylori (Hp)infection and IBS is not clarified yet. Aims:To investigate the role of Hp eradication in diarrhea-predominant IBS (IBS-D)and the relationship between Hp infection and IBS-D. Methods:A total of 335 IBS-D patients and 335 health examination subjects were recruited from Jan. 2009 to Dec. 2015 at Transportation Center Hospital of Yunnan Province and People's Hospital of Xishuangbanna Dai Autonomous Prefecture. All IBS-D patients were hospitalized patients and fulfilled the Rome Ⅲ criteria. Positive for both rapid urease test and 14 C-urea breath test was defined as Hp infection. Hp-positive IBS-D patients recruited in 2005 received Hp eradication therapy and were allocated into two groups according to the results of eradication therapy. Pinaverium bromide and montmorillonite powder were given in both groups and the clinical efficacy for IBS symptoms was assessed after treatment and followed up for 6 months. Results:The Hp infection rate of IBS-D patients was significantly higher than that in healthy controls (53. 7% vs. 41. 8%,P < 0. 05). In IBS-D patients received Hp eradication therapy,51 were allocated into eradicated group and 26 into non-eradicated group. No significant differences were observed in individual symptoms including abdominal pain/discomfort,bloating and stool frequency and the overall efficacy for global symptoms (68. 6% vs. 65. 4%)between the two groups (P > 0. 05). After a 6-month follow up,the differences were still insignificant (P > 0. 05). Conclusions:Hp infection is more prevalent in IBS-D patients than in general population,however,eradication of Hp has no impact on IBS symptoms. The association between Hp infection and IBS-D needs further study.
5."Some Suggestions on Teaching the Course of""Meridians and Acupoints"""
Lifang CHEN ; Ruijie MA ; Xianming LIN
Journal of Zhejiang Chinese Medical University 2017;41(2):168-170
[Objective]To improve the teaching quality ofMeridians and Acupoints. [Methods]Based on the ten-year experience of teaching the course ofMeridians and Acupoints, the authors suggest three issues on how to study well with this subject. [Results] The first, using the comparing method to remember meridians and acupoints, always do analysis and summary are all important ways to learn the basic knowledge.The second, understanding the property of acupoints, make prescription of acupoints like the way of making Chinese herbal formula according to syndrome differentiation, can cultivate students' dialectical thinking and improve the ability of diagnosis and treatment in acupuncture clinic.The third, introducing the origin,history and development of each meridian and some special acupoints. [Conclusion]The above three suggestions can help students to learn better about the science of acupuncture,and improve their professional thinking, and mine the potential ability of innovation.
6.Influence of early operation treatment for snoring children on intelligence development
Weinan CHEN ; Xinglong QIN ; Lifang DENG
Chinese Journal of Primary Medicine and Pharmacy 2014;21(1):12-13
Objective To explore the early surgical treatment for sleep apnea in children with the influence of mental development,provide important basis for children with sleep apnea early surgery.Methods 40 children with sleep apnea underwent bilateral amygdala and/or adenoidectomy (observation group).The Chinese wechsler intelligence scale for children (C-WYCSI) was used for preoperative and postoperative 6 months of intelligence tests,including language IQ and operation IQ test two parts,a total of 11 points.Operation IQ but also contain visual analysis test(VA) and two categories,including geometry test (GD).According to the 1 ∶ 1 matching selection of the same gender,and age(± 3 months),family condition was quite healthy check-up preschool children comparing 40 cases as control group.Results Observation group preoperative total intelligence quotient (IQ),verbal IQ,IQ operation was 82,81,83,respectively,which were lower than those of the control group 101,101,101 (t =4.131,3.952,3.842,all P < 0.05).Postoperative total intelligence quotient(IQ),verbal IQ and operation IQ 98,98,99,respectively,were in normal range,with no statistically significant difference were observed in the control group (all P > 0.05).Conclusion Children with sleep apnea early surgical treatment can improve children mental development.Children with sleep apnea early,breathing and surgical indications should be early surgical treatment.
7.Characteristic features of clinical manifestation, imaging and pathology of hypertrophic cranial pachymeningitis (report of 1 case)
Bing CHEN ; Xiaosu YANG ; Lifang ZHANG
Journal of Clinical Neurology 1992;0(01):-
Objective To determine the characteristic features of clinical manifestation, imaging and pathology in the patients with hypertrophic cranial pachymeningitis (HCP). Methods All clinical data of 1 patient with HCP were studied retrospectively. Results The patient presented with heavy headache, progressive visual acuity decreased and hoarse voice. Brain MRI displayed abnormal strengthening signals in cerebral dura mater, especially in cerebral falx and tentorium of cerebellum. Pathological examination demonstrated chronic inflammation changes including numerous plasmocytes infiltration, accrementition and glassy degeneration of fibrous tissue, formation of granulation tissue. Therapy with corticosteroid hormone showed good effect for this patient.Conclusions HCP mainly presents with headache and paralysis of multiple cranial nerves. Distinctive sign on brain MRI is strengthening signal in cerebral dura. Chronic inflammation is the pathological change of this disease and pathological examination plays important role in diagnosis of HCP.
8.Diagnostic value of urine RBP,NAG combined with serum CysC detection in early kidney damage in type 2 diabetes mellitus
Dan LU ; Lifang CHEN ; Jiedan CAI
International Journal of Laboratory Medicine 2016;37(7):928-929,932
Objective To explore the diagnostic value of urine retinol binding protein (RBP) ,beta‐N‐acetyl amino glycosidase enzymes(NAG) combined with serum cystatin C (CysC) detection in early kidney damage of type 2 diabetes mellitus (T2DM ) . Methods Totally 58 cases of T2DM complicating in our hospital were selected as the group A ,54 cases of simple T2DM (group B) and 52 individuals undergoing the physical examination(group C) .The urine RBP ,NAG and serum CysC were detected in three groups ,their differences were compared .The positive rates for detecting early diabetic renal damage were compared between the single index detection and combined detection .Results The levels of urine RBP ,NAG and serum CysC level in the group A were significantly higher than those in the group B and C ,the differences were statistically significant (P< 0 .05);the levels of urine RBP ,NAG and serum CysC level in the group B were significantly higher than those in the group C ,the differences were statistical‐ly significant(P<0 .05);The positive rates of single detection of RBP ,NAG and CysC were 87 .93% ,86 .21% and 84 .48% respec‐tively ,the positive rate of 3‐index combined detection was 94 .83% ,which was significantly higher than that of single index detec‐tion ,the difference was statistically significant (P<0 .05) .Conclusion Urine RBP ,NAG and serum CysC are the sensitive indexes in early diabetic renal damage .The 3‐index combined detection has better comprehensive sensitivity and possesses higher clinical ap‐plication value .
9.A Structural Equation Model of Stress,Coping Style,Social Support and Subjective Well-being for College Students
Lifang CHEN ; Shaobin MA ; Cunxin FAN
Chinese Journal of Clinical Psychology 2001;0(03):-
Objective: To explore the association between stress, coping style, social support and subjective well-being (SWB) of college Students. Methods: 1773 college students from 8 colleges in Guangzhou were tested with Index of Well-being Questionnaire, College Students’ Stress Scale, Simplified Coping Style Questionnaire(SCSQ) and Social Support Rating Scale (SSRS). And structural equation model (SEM) was built based on the data. Results: SEM revealed ?2/df=2.837, RMSEA=0.032, and indexes of GFI、AGFI、NFI、NNFI、CFI were all above 0.9. Stress and passive coping style had passive effect on SWB (the overall regression weights were -0.377 and -0.130 respectively). Social support and positive coping style had positive effect on SWB (the overall regression weights were 0.286 and 0.277 respectively). Conclusion: Stress, coping style and social support are important forecast variables of SWB.
10.A Clinical Study on Intelligence, Individuality and Behavior Characteristics in Epilepsy Children with Sub-clinical Seizure
Lifang MU ; Yingcai CHEN ; Dan XIE
Journal of Chinese Physician 2001;0(10):-
Objective To investigate the intelligence, individuality and behavior characteristics of epilepsy children with sub-clinical seizure. Methods The intelligence, individuality and behavior characteristics of the patients and normal age-matched children were evaluated by WISC, EPQ and CBCL. Results Compared with normal age-matched children, the code and number of WISC were obviously decreased in the children with epilepsy (P