Objective:To explore causes and inducement in aged patients with acute heart failure (AHF)and provide reference for clinical prevention and treatment of AHF.Methods:A total of 213 AHF patients,who hospitalized in Shenzhen Shekou People's Hospital from Jan 2010 to Dec 2013,were enrolled and divided into aged group (n=126) and youth and middle-aged group (n=87),incidence of causes and inducement were compared and analyzed between two groups.Results:Compared with youth and middle-aged group,there were significant rise in percentages of cor-onary heart disease (17.24% vs.72.22%)and hypertension (10.34% vs.34.13%),and significant reductions in percentages of valvular heart disease (12.70% vs.4.76%),cardiomyopathy (35.63% vs.7.14%)and congenital heart disease (26.44% vs.5.56%)in aged group,P <0.01 all.For the cause aggregation,percentage of multi-cause in aged group was significantly higher than that of youth and middle-aged group (39.68% vs.17.24%),while percentage of single-cause in youth and middle-aged group was significantly higher than that of aged group (82.76%vs.60.32%),P <0.01 both;the most frequent inducement was infection in both group,but there was no signifi-cant difference between two groups,P >0.05. Conclusion:Cause constitution is different among patients with acute heart failure and different age.The cause is complex and it′s mainly is coronary heart disease and hypertension in aged patients,and multiple factors work together.The target prevention and treatment should be taken according to the actual condition.

Objective To discuss the non-antibiotic Chinese medicine therapy for the non-gonococcus conjunctivitis in newborns, and reduce the use of antibiotic and the production of bear-medicine-bacterium. Methods 0.9%-sodium chloride was used as the inoculation fluid, Shuanghuanglian (freezing and drying) was uscd as dissolution injection. Dexamethasone sodium phosphate injection 1ml: 5mg was added, mixed-fluid 16ml was matched to spray the eyes after ultrasonic-atomization equipment atomizes. Results 56 examples 103 eyes which had the nongonococcus conjunctivitis in newborns were treated only with the injection with the Shuanghuanglian dexamethasone sodium phosphate injection mixed with the fluided ultrasonic-atomization equipment atomizes and the total effectiveness reached 97.08%. Conclusion The Shuanghuanglian-ultrasonic-atomization way to treat non-gonococcal conjunctivitis in the newborns is safe and effective.

Background:Irritable bowel syndrome (IBS)is a commonly seen functional intestinal disorder. The association between Helicobacter pylori (Hp)infection and IBS is not clarified yet. Aims:To investigate the role of Hp eradication in diarrhea-predominant IBS (IBS-D)and the relationship between Hp infection and IBS-D. Methods:A total of 335 IBS-D patients and 335 health examination subjects were recruited from Jan. 2009 to Dec. 2015 at Transportation Center Hospital of Yunnan Province and People's Hospital of Xishuangbanna Dai Autonomous Prefecture. All IBS-D patients were hospitalized patients and fulfilled the Rome Ⅲ criteria. Positive for both rapid urease test and 14 C-urea breath test was defined as Hp infection. Hp-positive IBS-D patients recruited in 2005 received Hp eradication therapy and were allocated into two groups according to the results of eradication therapy. Pinaverium bromide and montmorillonite powder were given in both groups and the clinical efficacy for IBS symptoms was assessed after treatment and followed up for 6 months. Results:The Hp infection rate of IBS-D patients was significantly higher than that in healthy controls (53. 7% vs. 41. 8%,P < 0. 05). In IBS-D patients received Hp eradication therapy,51 were allocated into eradicated group and 26 into non-eradicated group. No significant differences were observed in individual symptoms including abdominal pain/discomfort,bloating and stool frequency and the overall efficacy for global symptoms (68. 6% vs. 65. 4%)between the two groups (P > 0. 05). After a 6-month follow up,the differences were still insignificant (P > 0. 05). Conclusions:Hp infection is more prevalent in IBS-D patients than in general population,however,eradication of Hp has no impact on IBS symptoms. The association between Hp infection and IBS-D needs further study.

OBJECTIVE: To explore the regularity and characteristics of ADR cases induced by Fat emulsion injection, and to provide reference for rational use of it. METHODS: Retrieved from Chinese medical science periodicals from Jan. 1990 to Apr. 2010, 97 ADR cases induced by Fat emulsion injection were analyzed statistically. RESULTS: Main clinical manifestations of ADR cases induced by Fat emulsion injection were allergy reaction, followed by fat overloading syndrome, central nervous system reaction. The majority of ADR cases broke out in the first time of medication within 2 hour. CONCLUSION: It is essential for clinical practitioners to master the characteristics of ADR cases caused by Fat emulsion injection so as to promote safety of drug use.

Objective To explore the early surgical treatment for sleep apnea in children with the influence of mental development,provide important basis for children with sleep apnea early surgery.Methods 40 children with sleep apnea underwent bilateral amygdala and/or adenoidectomy (observation group).The Chinese wechsler intelligence scale for children (C-WYCSI) was used for preoperative and postoperative 6 months of intelligence tests,including language IQ and operation IQ test two parts,a total of 11 points.Operation IQ but also contain visual analysis test(VA) and two categories,including geometry test (GD).According to the 1 ∶ 1 matching selection of the same gender,and age(± 3 months),family condition was quite healthy check-up preschool children comparing 40 cases as control group.Results Observation group preoperative total intelligence quotient (IQ),verbal IQ,IQ operation was 82,81,83,respectively,which were lower than those of the control group 101,101,101 (t =4.131,3.952,3.842,all P ＜ 0.05).Postoperative total intelligence quotient(IQ),verbal IQ and operation IQ 98,98,99,respectively,were in normal range,with no statistically significant difference were observed in the control group (all P ＞ 0.05).Conclusion Children with sleep apnea early surgical treatment can improve children mental development.Children with sleep apnea early,breathing and surgical indications should be early surgical treatment.

Objective To determine the characteristic features of clinical manifestation, imaging and pathology in the patients with hypertrophic cranial pachymeningitis (HCP). Methods All clinical data of 1 patient with HCP were studied retrospectively. Results The patient presented with heavy headache, progressive visual acuity decreased and hoarse voice. Brain MRI displayed abnormal strengthening signals in cerebral dura mater, especially in cerebral falx and tentorium of cerebellum. Pathological examination demonstrated chronic inflammation changes including numerous plasmocytes infiltration, accrementition and glassy degeneration of fibrous tissue, formation of granulation tissue. Therapy with corticosteroid hormone showed good effect for this patient.Conclusions HCP mainly presents with headache and paralysis of multiple cranial nerves. Distinctive sign on brain MRI is strengthening signal in cerebral dura. Chronic inflammation is the pathological change of this disease and pathological examination plays important role in diagnosis of HCP.

Objective: To explore the association between stress, coping style, social support and subjective well-being (SWB) of college Students. Methods: 1773 college students from 8 colleges in Guangzhou were tested with Index of Well-being Questionnaire, College Students’ Stress Scale, Simplified Coping Style Questionnaire(SCSQ) and Social Support Rating Scale (SSRS). And structural equation model (SEM) was built based on the data. Results: SEM revealed ?2/df=2.837, RMSEA=0.032, and indexes of GFI、AGFI、NFI、NNFI、CFI were all above 0.9. Stress and passive coping style had passive effect on SWB (the overall regression weights were -0.377 and -0.130 respectively). Social support and positive coping style had positive effect on SWB (the overall regression weights were 0.286 and 0.277 respectively). Conclusion: Stress, coping style and social support are important forecast variables of SWB.

Objective To investigate the intelligence, individuality and behavior characteristics of epilepsy children with sub-clinical seizure. Methods The intelligence, individuality and behavior characteristics of the patients and normal age-matched children were evaluated by WISC, EPQ and CBCL. Results Compared with normal age-matched children, the code and number of WISC were obviously decreased in the children with epilepsy (P

Objective T o explore the casual relationship and the significance of identification am ong the injury, disease and dam age consequence in the disability evaluation of lum bar spondylolysis by the stan-dard for identifying grading of disability caused by w ork-related injuries. Methods T he general data, in-jury m anner, clinical treatm ent and the im aging exam ination of 32 lum bar spondylolysis cases w ere col-lected and retrospectively analyzed. A ccording to the degree of participation in the injury and dam age consequence, the identification and assessm ent of casual relationship w as m ade, and the grading of dis-ability w as assessed. Results For 32 cases, injury had no effect on dam age consequence in 7 cases, slight effect in 5 cases, secondary effect in 13 cases, equivalent effect in 4 cases, and com plete effect in 3 cases. A ccording to the related item s in the standard for identifying grading of disability caused by w ork-related injuries, 3 cases w ere rated level 7, 5 cases w ere level 8, 6 cases w ere level 9, 11 cases w ere level 11 am ong the cases w hich existed causal relationship. Conclusion T he form ation of lum bar spondylolysis is connected to the factors of age, anatom y, occupation and injury m anner etc. T he degree of disability should be accessed com prehensively after the analysis of the casual relationship am ong the injury, disease and dam age consequence.

Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder caused by the lack of expression of genes associated with the 15q11.2-q13 region of the paternal chromosome.There are three main types of genetic mechanisms, deletion of the paternal critical region, maternal uniparental disomy and imprinting center defect.Genetic counseling can be carried out based on different genetic mechanisms of PWS, both re-fertility assessments and prenatal diagnoses were performed on couples whose children have already had the disease.The pathogeny and mechanism of PWS are complex.The rapid development of molecular genetics and related research have provided a basis for further understanding of this disease.In this paper, the advances in the genetics of PWS were reviewed.