In China, cooking oil fume is a kind of indoor air pollutant that is ubiquitous. With the development of catering trade, the pollution of cooking oil fume is becoming more and more severe. The results of animal experiments showed that cooking oil fume could damage the genetic substance and cause cancer. The results from the epidemiological studies indicated that cooking oil fume could induce lipid peroxidation and change the pulmonary and immunologic functions, cause chromosome damage and increase the risk of lung cancer.

The academic origin and characteristics of medical families of acupuncture-moxibustion in northern Zhejiang Province were explored in this paper. With acupuncture-moxibustion characteristic of medical families in northern Zhejiang Province such as the LING (see text), the YAN (see text), the SHI (see text) and the SHENG (see text) analyzed and arranged, it was found out that taking the Internal Canon of Medicine as theory basis, their academic thoughts comprehensively absorbed acupuncture-moxibustion theories in all ages, and they continuously made innovations through constant practices, resulting in academic thoughts that focusing on application of acupuncture-moxibustion in clinic, using moxibustion for deficient illness and adopting acupuncture-moxibustion and Chinese herbs for severe and acute patients. The academic thoughts of medical families of acupuncture and moxibustion in northern Zhejiang Province are featured by unique acupoint selection and ma nipulation, thorough moxibustion methods and combined application of Chinese herbs and acupuncture-moxibustion, which is a clinical system of diagnosis and treatment with typical Jiangnan features.
Acupuncture ; education ; history ; Acupuncture Therapy ; history ; China ; History, Ancient ; Humans ; Moxibustion ; history

Objective To investigate the relationship between the changes of blood coagulation index before and after neoadjuvant chemotherapy and the chemotherapeutic efficacy in patients with breast cancer.Methods Ninety patients with breast cancer were selected,and detected the changes of blood coagulation index before and after neoadjuvant chemotherapy (TAC regimen),and the relationship between blood coagulation index and the chemotherapeutic efficacy were analyzed.Results The levels of fibrinogen (Fib),platelet count (PLT) after chemotherapy were significantly higher than those before chemotherapy [(3.42 ±0.50) g/L vs.(2.44 ±0.46) g/L,(267.83 ±61.34) × 109/L vs.(174.18 ±48.65) × 109/L] (P ＜ 0.01),D-dimer (D-D) was significantly lower than that before chemotherapy [(176.32 ± 101.41) mg/L vs.(214.55 ± 106.34) mg/L] (P ＜ 0.01).The remaining indicators before and after chemotherapy had no significant differences (P ＞ 0.05).The level of D-D in 68 cases was reduced after chemotherapy,the effective chemotherapy in 53 cases (77.9％,53/68),ineffective in 15 cases (22.1％,15/68);the level of D-D in 22 cases was increased after chemotherapy,the effective chemotherapy in 9 cases (40.9％,9/22),ineffective in 13 cases (59.1％,13/22),the difference was statistically significant (P=0.000).The level of PLT in 10 cases was reduced after chemotherapy,the effective chemotherapy in 3 cases(3/10),ineffective in 7 cases (7/10);the level of PLT in 80 cases was increased after chemotherapy,the effective chemotherapy in 59 cases (73.8％,59/80),ineffective in 21 cases (26.3％,21/80),the difference was statistically significant (P=0.044).Conclusions The Fib and PLT increase while the D-D decreases after chemotherapy,so it is necessary to monitor Fib,PLT,D-D level during chemotherapy.The D-D and PLT are effective indexes in evaluating curative effect of neoadjuvant chemotherapy in patients with breast cancer.

Objective To optimize the technology of extracting Paeoniflorin and Puerarin from Tongqing Granules. Methods The experiment used the orthogonal experimental design (4 factors and 3 levels) with the shift-rate of Paeoniflorin and Puerarin as experimental criterion in screening the factors affecting the technology of extracting Tongqing Granules. Results All the 3 factors designed in the orthogonal experiment non-signifantly affected the extracting technology. In consideration of the industrial practice, the best condition of extracting the constituents from Tongqing Granules was decided:water extraction for 3 times, extracting with 12 fold water for 1 hours for the first time, with 5 fold water for 0.5 hours for the second time, and with 5 fold water for 0.5 hour for the third time. Conclusion The condition is the optimized technology of extracting Paeoniflorin and Puerarin from Tongqing Granules.

Objective To study the effects of prolonged oxygen exposure at different concentrations on expressions of vascular endothelial growth factor (VEGF) and its receptors (VEGF receptor-1 ,VEGFR1 and VEGF receptor-2, VEGFR2)mRNA in lungs of neonatal rat. Methods Thirty-two SD rat pups were randomly divided into control and experimental group. Rats in the experimental group were further divided into three subgroups: 30% O2, 50% O2 and 75% O2 group. Each group had 8 rats. The rats were ,sacrificed at postnatal day 21 and their right lower lobes were collected. Expressions of VEGF, VEGFR1 and VEGFR2 mRNA were detected by RT-PCR. Results There was no effect on VEGF, VEGFR1 or VEGFR2 mRNA expression in 30% O2 group. The expressions of VEGF mRNA in the 75% O2 group was 0. 48 times of the control (P<0. 05). The expressions of VEGFR1 mRNA(P<0.01) and VEGFR2 mRNA (P<0.01) in 50% O2 and 75% O2 group were lower than those of control. Condusions Prolonged exposure to moderate or high oxygen concentration may reduce the expression of VEGF and its receptors' mRNA in the lung tissues of neonatal rats.

Objective To study the application value of medical absorbable suture in upper limb fingers extensor tendon injury.Methods According to the digital table,100 patients with upper limb fingers extensor tendon injury were randomly divided into the two groups.Patients in group A were repaired by medical absorbable suture,while patients in group B were repaired by tendon trocars.Functional evaluation and postoperative adverse reactions of the two groups were recorded after surgery.Results The total effective rate of group A (92.0％) was higher than that of group B (82.0％) (u =-2.596,P =0.009).The incidence rate of adverse reactions of group A was 14.0％ and which of group B was 10.0％,the difference was no significant (x2 =0.378,P =0.538).Conclusion Medical absorbable suture can effectively improve upper limb fingers extensor tendon injury treatment effect and significantly improve clinical symptoms.It's safe and the postoperative adverse reactions is less.

Objective To observe the effect of salvia miltiorrhiza injection on antioxygen free radicals and its efficacy on viral myocarditis. Methods 72 cases of patients with viral myocarditis were randomly divided into two groups.The traditional group with energy mixture,1.6-diphosphate fructose improving myocardial nutrition,bed rest,intensive use of glucocorticoid,selected the appropriate treatment for arrhythmia;salvia miltiorrhiza group in the control group treatment combined with salvia miltiorrhiza injection of 5 ~15 mL each time,dissolved in 5%glucose intravenous drip,once a day,2 weeks as a course of treatment.To observe two groups of manifestation,the change of myocardial enzyme spectrum and the comparative efficacy before and after the treatment.Through the detection of the treatment group and the control group of serum superoxide dismutase (SOD ), malondialdehyde (MDA)and other indicators to understand the antioxidant effect of salvia miltiorrhiza injection.36 healthy children were taken as control group,detected cardiac troponin (cTnT),high sensitive C reactive protein (hs-CRP),creatine kinase isoenzyme MB (CK-MB)and SOD in three groups,their correlations were evaluated as well.Results Compared with healthy children,the activity of SOD in salvia miltiorrhiza group was statistically significant (P<0.01).The activity of SOD increased significantly (P<0.01).SOD was negatively correlated with cTnT,hs-CRP and CK-MB levels (P<0.05 ).The curative effect of salvia miltiorrhiza group were significantly higher than that of the control group.CTnT,hs-CRP and CK-MB levels decreased significantly after treatment (P<0.05 ),which in salvia miltiorrhiza group decreased significantly than that of the control group.SOD activity increased value was higher than the traditional group (P<0.01 );the decrease in MDA was obvious than that of the traditional group (P<0.05 ).Conclusion Oxygen free radicals are involved in the pathogenesis of viral myocarditis;the efficacy of salvia miltiorrhiza injection in the treatment of viral myocarditis is proved of curative effect;antioxidant effect may be an important mechanism of salvia miltirrhiza injection in the treatment of viral myocarditis.

Modern fully automatic biochemical analyzer makes enzyme measurement accurate, specific and practical, but alarm failure happens sometimes and thus determinate error appears. To find out the inducement to alarm failure, Olympus AU2700 and ADVIA 1650 fully automatic biochemical analyzer are used to measure the serum liver enzyme from 450 cases of post-liver-transplantation patients.

Objective To discuss the clinical application and features of coronary artery bypass grafting(CABG) through left intercostal thoracotomy approach. Methods A total of 36 cases of CABG were performed through left intercostal thoracotomy approach from September 1996 to August 2005 in this hospital.The patients fell into four categories: ①single vessel disease in the left anterior descending artery(LAD);②re-operation of CABG with a patent LIMA(left internal mammary artery)-LAD bypass;③severe calcified ascending aorta;and ④concurrent other procedures that required left thoracotomy.There were 26 cases of single vessel disease,3 cases of double vessel disease,and 7 cases of triple vessel disease.Five cases had a history of percutaneous coronary interventions(PCIs) and 6 cases had a history of CABGs.The left ventricular ejection fraction was 0.562?0.107. Results Off pump CABG with 1~4 distal anastomosis was successfully accomplished in all the 36 cases,with an operation time of 190.4?44.1 min.Concurrent procedures included 2 cases of transmyocardial laser revascularization(TMLR),1 case of lung cancer resection,and 1 case of esophageal cancer resection.There was no in-hospital mortality.Two fatal cases were seen in long-term follow-up observations.Recurrent angina developed in 2 cases 1 year after operation,and was cured with a PCI in 1 case and with a re-operation of CABG in 1 case. Conclusions The left intercostal thoracotomy is a safe and feasible approach for CABG surgery in patients with some special types of coronary heart disease.The procedure can be performed under beating heart.

Ultrasonic is efficacious in curing bone injury.A suit of ultrasonic generator is developed for bone injury,which has a simple structure with good reliability.Besides the design principle and system scheme,the mechanism and application of ultrasonic therapy together with the key techniques such as wave-form producing,power adjusting and load coupling are analyzed.